Patents by Inventor Michael Kiffe

Michael Kiffe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Epothilons C and D, preparation and compositions
    Patent number: 6831076
    Abstract: The present invention relates to epothilon derivatives and to their use.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: December 14, 2004
    Assignee: Gesellschaft fur Biotechnologische Forschung mbH (GBF)
    Inventors: Gerhard Hoefle, Michael Kiffe
  • Epothilons C and D, preparation and compositions
    Publication number: 20040087634
    Abstract: The present invention relates to epothilon derivatives and to their use.
    Type: Application
    Filed: June 25, 2003
    Publication date: May 6, 2004
    Inventors: Gerhard Hoefle, Michael Kiffe
  • Epothilons C and D, preparation and compositions
    Patent number: 6613912
    Abstract: The present invention relates to epothilon derivatives and to their use.
    Type: Grant
    Filed: April 16, 2001
    Date of Patent: September 2, 2003
    Assignee: Gesellschaft fur Biotechnologische Forschung mbH (GBF)
    Inventors: Gerhard Hoefle, Michael Kiffe
  • Epothilons C and D, preparation and compositions
    Publication number: 20010034452
    Abstract: The present invention relates to epothilon derivatives and to their use.
    Type: Application
    Filed: April 16, 2001
    Publication date: October 25, 2001
    Inventors: Gerhard Hoefle, Michael Kiffe
  • Epothilons C and D, preparation and compositions
    Patent number: 6288237
    Abstract: The present invention relates to epothilon derivatives and to their use.
    Type: Grant
    Filed: August 3, 1998
    Date of Patent: September 11, 2001
    Assignee: Gesellschaft fur Biotechnologische Forschung mbH (GBF)
    Inventors: Gerhard Hoefle, Michael Kiffe
  • Method for recovering optically pure amino acid derivatives
    Patent number: 5670647
    Abstract: A method for recovering an optically pure amino acid derivative from a waste liquor collected after a coupling reaction in peptide synthesis, comprising the steps of (a) adding into the waste liquor, in which an uncoupled amino acid derivative or an uncoupled small peptide fragment is contained, a compound selected from the group consisting of 1-hydroxybenzotriazole (HOBt), 1-hydroxy-7-azabenzotriazole (HOAt), 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazine (HOObt) and N-hydroxy-5-norbornen-2,3-dicarboxylic acid imide(HONB); (b) concentrating the waste liquor obtained in step (a); (c) treating a residue obtained in step (b) with an acidic buffer solution containing a tertiary amine; and (d) extracting and purifying the uncoupled amino acid derivative or the uncoupled small peptide fragment under acidic conditions.
    Type: Grant
    Filed: March 1, 1996
    Date of Patent: September 23, 1997
    Assignee: Shimadzu Corporation
    Inventors: Kiyoshi Nokihara, Michael Kiffe