Patents by Inventor Michael Kinch

Michael Kinch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9673347
    Abstract: Disclosed are minority carrier based mercury-cadmium telluride (HgCdTe) infrared detectors and arrays, and methods of making, are disclosed. The constructions provided by the invention enable the detectors to be used at higher temperatures, and/or be implemented on less expensive semiconductor substrates to lower manufacturing costs. An exemplary embodiment a substrate, a bottom contact layer disposed on the substrate, a first mercury-cadmium telluride layer having a first bandgap energy value disposed on the bottom contact layer, a second mercury-cadmium telluride layer having a second bandgap energy value that is greater than the first bandgap energy value disposed on the first mercury-cadmium telluride layer, and a collector layer disposed on the second mercury-cadmium telluride layer, wherein the first and second mercury-cadmium telluride layers are each doped with an n-type dopant.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: June 6, 2017
    Assignee: DRS Network & Imaging Systems, LLC
    Inventors: Michael A. Kinch, Christopher A. Schaake
  • Publication number: 20150318418
    Abstract: Disclosed are minority carrier based mercury-cadmium telluride (HgCdTe) infrared detectors and arrays, and methods of making, are disclosed. The constructions provided by the invention enable the detectors to be used at higher temperatures, and/or be implemented on less expensive semiconductor substrates to lower manufacturing costs. An exemplary embodiment a substrate, a bottom contact layer disposed on the substrate, a first mercury-cadmium telluride layer having a first bandgap energy value disposed on the bottom contact layer, a second mercury-cadmium telluride layer having a second bandgap energy value that is greater than the first bandgap energy value disposed on the first mercury-cadmium telluride layer, and a collector layer disposed on the second mercury-cadmium telluride layer, wherein the first and second mercury-cadmium telluride layers are each doped with an n-type dopant.
    Type: Application
    Filed: July 16, 2015
    Publication date: November 5, 2015
    Inventors: Michael A. Kinch, Christopher A. Schaake
  • Patent number: 9112098
    Abstract: Disclosed are minority carrier based mercury-cadmium telluride (HgCdTe) infrared detectors and arrays, and methods of making, are disclosed. The constructions provided by the invention enable the detectors to be used at higher temperatures, and/or be implemented on less expensive semiconductor substrates to lower manufacturing costs. An exemplary embodiment a substrate, a bottom contact layer disposed on the substrate, a first mercury-cadmium telluride layer having a first bandgap energy value disposed on the bottom contact layer, a second mercury-cadmium telluride layer having a second bandgap energy value that is greater than the first bandgap energy value disposed on the first mercury-cadmium telluride layer, and a collector layer disposed on the second mercury-cadmium telluride layer, wherein the first and second mercury-cadmium telluride layers are each doped with an n-type dopant.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: August 18, 2015
    Assignee: DRS Network & Imaging Systems, LLC
    Inventors: Michael A. Kinch, Christopher A. Schaake
  • Patent number: 8796423
    Abstract: The present invention provides antibodies that bind to the C-terminal region of TSG101. The invention also provides methods of using the TSG101 antibodies for the treatment of viral infections, including HIV and Ebola virus infection.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: August 5, 2014
    Assignee: Eli Lilly and Company
    Inventors: Limin Li, Michael Kinch, Michael Goldbiatt
  • Publication number: 20140147962
    Abstract: Disclosed are minority carrier based mercury-cadmium telluride (HgCdTe) infrared detectors and arrays, and methods of making, are disclosed. The constructions provided by the invention enable the detectors to be used at higher temperatures, and/or be implemented on less expensive semiconductor substrates to lower manufacturing costs. An exemplary embodiment a substrate, a bottom contact layer disposed on the substrate, a first mercury-cadmium telluride layer having a first bandgap energy value disposed on the bottom contact layer, a second mercury-cadmium telluride layer having a second bandgap energy value that is greater than the first bandgap energy value disposed on the first mercury-cadmium telluride layer, and a collector layer disposed on the second mercury-cadmium telluride layer, wherein the first and second mercury-cadmium telluride layers are each doped with an n-type dopant.
    Type: Application
    Filed: January 29, 2014
    Publication date: May 29, 2014
    Applicant: DRS RSTA, INC.
    Inventors: Michael A. Kinch, Christopher A. Schaake
  • Patent number: 8686471
    Abstract: Disclosed are minority carrier based mercury-cadmium telluride (HgCdTe) infrared detectors and arrays, and methods of making, are disclosed. The constructions provided by the invention enable the detectors to be used at higher temperatures, and/or be implemented on less expensive semiconductor substrates to lower manufacturing costs. An exemplary embodiment a substrate, a bottom contact layer disposed on the substrate, a first mercury-cadmium telluride layer having a first bandgap energy value disposed on the bottom contact layer, a second mercury-cadmium telluride layer having a second bandgap energy value that is greater than the first bandgap energy value disposed on the first mercury-cadmium telluride layer, and a collector layer disposed on the second mercury-cadmium telluride layer, wherein the first and second mercury-cadmium telluride layers are each doped with an n-type dopant.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: April 1, 2014
    Assignee: DRS RSTA, Inc.
    Inventors: Michael A. Kinch, Christopher A. Schaake
  • Publication number: 20120273838
    Abstract: Disclosed are minority carrier based mercury-cadmium telluride (HgCdTe) infrared detectors and arrays, and methods of making, are disclosed. The constructions provided by the invention enable the detectors to be used at higher temperatures, and/or be implemented on less expensive semiconductor substrates to lower manufacturing costs. An exemplary embodiment a substrate, a bottom contact layer disposed on the substrate, a first mercury-cadmium telluride layer having a first bandgap energy value disposed on the bottom contact layer, a second mercury-cadmium telluride layer having a second bandgap energy value that is greater than the first bandgap energy value disposed on the first mercury-cadmium telluride layer, and a collector layer disposed on the second mercury-cadmium telluride layer, wherein the first and second mercury-cadmium telluride layers are each doped with an n-type dopant.
    Type: Application
    Filed: December 14, 2011
    Publication date: November 1, 2012
    Inventors: Michael A. Kinch, Christopher A. Schaake
  • Patent number: 8207209
    Abstract: A method of inhibiting viral respiratory infection in a mammal in need of same, includes administering an effective amount of 2-[2-(5-carbamimidoyl-benzofuran-2-yl)-vinyl]-H-benzoimidazole-5-carboxamidine or the Bis-N-hydroxyamidine prodrug thereof, prior to viral infection, or therapeutically following viral infection, to inhibit that viral infection. The compound selectively inhibits Caspase 2 and/or 8 as to prevent infective viral particle release. It is optionally administered IV, IP, orally or via other conventional administration routes in a dosage range of 1 ng/kg-200 mg/kg of body weight.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: June 26, 2012
    Assignee: Functional Genetics, Inc.
    Inventors: Michael Kinch, Michael Goldblatt
  • Publication number: 20120142731
    Abstract: Compounds, pharmaceutical compositions and methods of inhibiting viral infection in a mammal in need of same, are provided, which employ compounds of the formula wherein each X is independently H or an electrodonating group, each Y is independently H, alkyl of 1-4 carbon atoms, hydroxy, alkoxy or methylene and wherein Substituent Z is a di-or-tri akly amino, or alkyl di or tri amino, optionally substituted with a halogen moiety. This family of compounds, designated FGI-104 herein, inhibits viral infection therapeutically and prophylactically.
    Type: Application
    Filed: October 30, 2008
    Publication date: June 7, 2012
    Applicant: Functional Genetics, Inc.
    Inventors: Michael Kinch, Michael Goldblatt
  • Publication number: 20110287019
    Abstract: The invention provides for inhibition of viral disease by the provision to a mammalian host of antibodies directed against an escort protein like Tsg101. These proteins appear on the surface of a cell, and thus can be bound by circulating antibodies thereto. By binding escort proteins on the cell surface, budding of viral particles is inhibited. The virus infects the initial cells, but cannot escape that cell to infect the body en masse.
    Type: Application
    Filed: June 13, 2011
    Publication date: November 24, 2011
    Applicant: FUNCTIONAL GENETICS, INC.
    Inventors: ROXANNE DUAN, MICHAEL KINCH, MICHAEL GOLDBLATT
  • Publication number: 20110206695
    Abstract: XMRV appears to be related to both prostate cancer if it infects a male germ cell and chronic fatigue syndrome in both sexes. (If the virus does not infect a germ cell). Prostate cancer cells exhibit TSG101 on the surface only upon infection with a virus like XMRV. Antibodies to TSG101 can be effective diagnostics to identify individuals with a predisposition to prostate. They can also be used in place of current diagnostics to confirm the presence of prostate cancer. TSG101 antibodies, when administered in vivo, exhibit the ability to reduce tumor size, suppress metastatic transformation and extend survival.
    Type: Application
    Filed: January 25, 2011
    Publication date: August 25, 2011
    Applicant: FUNCTIONAL GENETICS, INC.
    Inventors: Manu Kohli, Michael Goldblatt, Michael Kinch
  • Patent number: 7981410
    Abstract: The invention provides for inhibition of viral disease by the provision to a mammalian host of antibodies directed against an escort protein likeTsg 101. These proteins appear on the surface of a cell, and thus can be bound by circulating antibodies thereto. By binding escort proteins on the cell surface, budding of viral particles is inhibited. The virus infects the initial cells, but cannot escape that cell to infect the body en masse.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: July 19, 2011
    Assignee: Functional Genetics, Inc.
    Inventors: Roxanne Duan, Michael Kinch, Michael Goldblatt
  • Publication number: 20110152343
    Abstract: Caspace inhibition provides inhibition of viral infection across a wide collection of caspaces and viruses. Caspace inhibition, the prevention of the formation of active caspaces, can be achieved either through gene therapy, protein binding an inhibition, or through small molecule administration. Examples for small molecule inhibition allow the formation of a pharmacaphore to identify more and more active small molecules.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 23, 2011
    Applicant: Functional Genetics, Inc.
    Inventors: M. JAVAD AMAN, Michael Kinch, Sven Enterlein, Yunus Abdul
  • Patent number: 7964708
    Abstract: The present invention provides antibodies that bind to the C-terminal region of TSG101. The invention also provides methods of using the TSG101 antibodies for the treatment of viral infections, including HIV and Ebola virus infection.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: June 21, 2011
    Inventors: Limin Li, Michael Kinch, Michael Goldblatt, Roxanne Duan
  • Publication number: 20100286248
    Abstract: A human gene, fg01, on chromosome 8, is identified. This gene, and its expression product, human fg01, shares a homology under 70% with the corresponding murine gene, which has been linked to presentation of the Alzheimer's phenotype of A? plaques and hyperphosphorylated tau tangles. Upregulation appears to suppress the Alzheimer's phenotype, which may be effective in preventing the onset of symptoms or progression of symptoms associated with AD. Screening methods are also set forth.
    Type: Application
    Filed: September 25, 2009
    Publication date: November 11, 2010
    Applicant: Functional Genetics, Inc.
    Inventors: WU-BO LI, MICHAEL KINCH, MICHAEL GOLDBLATT
  • Publication number: 20100286252
    Abstract: A human gene, fg01, on chromosome 8, is identified, as well as a truncated form on chromosome 5. Upregulation appears to suppress the Alzheimer's phenotype, (AB plaques and hyperphosphorylated tau tangles) which may address the onset of symptoms or progression of symptoms associated with AD. Screening methods are also set forth.
    Type: Application
    Filed: May 10, 2010
    Publication date: November 11, 2010
    Applicant: Functional Genetics, Inc.
    Inventors: Wu-Bo LI, Michael Kinch, Michael Goldblatt
  • Publication number: 20090285819
    Abstract: Genes relating to resistance to infection by influenza virus are identified. The genes and the gene products (i.e., the polynucleotides transcribed from and polypeptides encoded by the genes) can be used for the prevention and treatment of influenza. The genes and the gene products can also be used to screen agents that modulate the gene expression or the activities of the gene products.
    Type: Application
    Filed: November 15, 2007
    Publication date: November 19, 2009
    Applicant: Functional Genetics, Inc.
    Inventors: Limin Li, Michael Kinch, Michael Goldblatt
  • Patent number: 7612340
    Abstract: An avalanche photodiode is operated in avalanche mode at a selected reverse bias that achieves high gain and a reduced gain normalized dark current.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: November 3, 2009
    Assignee: DRS Sensors & Targeting Systems, Inc.
    Inventors: Jeffrey Don Beck, Pradip Mitra, Chang-Feng Wan, Michael A. Kinch
  • Patent number: 7608830
    Abstract: A photodiode for detection of preferably infrared radiation capable of detecting two different wavelengths wherein photons are absorbed in one region and detected in another. In one example embodiment, an absorbing P region is abutted with an N region of lower doping such that the depletion region is substantially (preferably completely) confined to the N region. The N region is also chosen with a larger bandgap than the P region, with compositional grading of a region of the N region near the P region. This compositional grading mitigates the potential barrier between the respective bandgaps. Under first voltage conditions a potential barrier prevents minority carriers from moving from the P region to the N region, but photons of energy large enough to generate minority carriers within the N region are detected. Under reverse bias, the barrier is substantially reduced or disappears, allowing charge carriers to move from the absorbing P region into the N region (and beyond) where they are detected.
    Type: Grant
    Filed: October 13, 2005
    Date of Patent: October 27, 2009
    Assignee: DRS Sensors & Targeting Systems, Inc.
    Inventor: Michael A. Kinch
  • Publication number: 20090220527
    Abstract: The present invention relates to antibodies with increased affinities that preferentially bind an EphA2 epitope exposed on cancer cells but not non-cancer cells. The present invention further relates to methods and compositions designed for the treatment, management, or prevention of cancer, particularly, metastatic cancer. The invention also provides pharmaceutical compositions comprising one or more EphA2 antibodies of the invention either alone or in combination with one or more other agents useful for cancer therapy.
    Type: Application
    Filed: December 20, 2006
    Publication date: September 3, 2009
    Applicant: MEDLMMUNE, LLC
    Inventors: Melissa Damschroder, William Dall'Acqua, Herren Wu, Michael Kinch