Patents by Inventor Michael Kirisits

Michael Kirisits has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fab I and inhibition of apicomplexan parasites
    Publication number: 20090156687
    Abstract: Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases.
    Type: Application
    Filed: November 5, 2007
    Publication date: June 18, 2009
    Inventors: Rima McLeod, Michael Kirisits, Dennis Kyle, Douglas G. Mack, Wilbur Milhous, Stephen Muench, Ernest J. Mui, Sean Prigge, John Rafferty, David Rice, Craig W. Roberts, Benjamin Samuel
  • Antimicrobial agents, diagnostic reagents, and vaccines based on unique apicomplexan parasite components
    Publication number: 20050142113
    Abstract: This invention relates uses of components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on the components and their inhibitors.
    Type: Application
    Filed: April 14, 2004
    Publication date: June 30, 2005
    Inventors: Rima McLeod, Craig Roberts, Fiona Roberts, Jennifer Johnson, Michael Kirisits, David Ferguson, Russell Lyons, Ernest Mui, Doug Mack, Benjamin Samuel, Piotr Gornicki, Ellen Zuther
  • Antimicrobial agents, diagnostic reagents, and vaccines based on unique Apicomplexan parasite components
    Patent number: 6737237
    Abstract: This invention relates uses of Toxoplasma gondii chorismate synthase, a component components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, in assays to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on T. gondii chorismate synthase and its inhibitors.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: May 18, 2004
    Assignee: Apicomplexan Therapeutics, LLC
    Inventors: Rima L. McLeod, Craig W. Roberts, Fiona Roberts, Jennifer J. Johnson, Michael Kirisits, David Ferguson, Russell Lyons, Ernest Mui, Doug Mack, Benjamin Samuel, Piotr Gornicki, Ellen Zuther
  • Apicomplexan chorismate synthase sequences and an inhibitor of the shikimate pathway
    Publication number: 20030186352
    Abstract: This invention relates uses of components of plant-like metabolic pathways not including psbA or PPi phosphofructokinase and not generally operative in animals or encoded by the plastid DNA, to develop compositions that interfere with Apicomplexan growth and survival. Components of the pathways include enzymes, transit peptides and nucleotide sequences encoding the enzymes and peptides, or promoters of these nucleotide sequences to which antibodies, antisense molecules and other inhibitors are directed. Diagnostic and therapeutic reagents and vaccines are developed based on the components and their inhibitors.
    Type: Application
    Filed: October 10, 2002
    Publication date: October 2, 2003
    Inventors: Rima L. McLeod, Michael Kirisits, Craig W. Roberts, Doug Mack, Ernest Mui, John Barnwell, John Dame, Jane Carlton, Paul Bartlett, Suzanna Parle