Abstract: The present invention provides N-methylated cyclic hexapeptides comprising RGD and at least one alanine residue. The present invention further provides prodrugs comprising the cyclic hexapeptides. Pharmaceutical compositions comprising said cyclic hexapeptides are also disclosed as well as methods of their production and use in treating integrin related conditions and diseases.

Abstract: A control unit and a method are provided for controlling a riding function of a two-wheeled vehicle. The riding function is configured to guide the two-wheeled vehicle longitudinally and/or transversely in an automated manner. The control unit is configured to detect that the riding function is activated in order to bring about automated longitudinal and/or transverse guidance by the riding function, to determine that dynamic adaptation of the riding function is requested by the driver, and in response thereto, to initiate that, with the riding function being active, a control parameter influencing the dynamics of the riding function is adapted on the basis of the requested dynamic adaptation.

Abstract: A device for generating a liquid film of a liquid medium in a film bag includes two accumulating surfaces spaced apart by an accumulating distance (A), between which the film bag can be arranged and transported along a transport direction; a braking element arranged downstream of the accumulating surfaces in the transport direction, which braking element is arranged to brake the film bag; with a running surface which is convexly curved in the transport direction and is set up and arranged in such a way that the film bag braked by the braking element can be spanned on the running surface behind the braking element. At least a first accumulating surface of the two accumulating surfaces is formed at least in regions by a driven first conveyor belt which is arranged to convey the film bag in the transport direction.

Abstract: Means and methods for dispensing small amounts of liquid from multi-channel microdispensing devices, suitable for use in automatic processing in biological assays and for the cultivation of cells and tissues, by means of optical control of the dosed liquid by specific light barrier units.

Abstract: The present invention relates to novel Toll-like Receptor (TLR) agonist compositions that can demonstrate enhanced innate immune responses, improved stability and lower toxicity than said agonists alone. These immunomodulators comprise one or more TLR agonists linked to glycogen-based nanoparticles. Also provided are processes for manufacturing, and methods of using the compositions to induce therapeutic immune responses.

Abstract: An anti-infective composition comprising glycogen or phytoglycogen nanoparticles is provided.

Abstract: Means and methods for dispensing small amounts of liquid from multi-channel microdispensing devices, suitable for use in automatic processing in biological assays and for the cultivation of cells and tissues, by means of optical control of the dosed liquid by specific light barrier units.