Abstract: Disclosed is a broad variety of triterpene glycosides extracted from Momoridica grosvenori as sweeteners and sweetness enhancers.

Abstract: Described are tetravalent, bispecific EGFR/CD16A antigen-binding proteins for engaging NK-cells towards EGFR-positive cells. EGFR/CD16A antigen-binding proteins with different pharmacokinetic (PK) properties are described. Further described is the use of bispecific EGFR/CD16A antigen-binding proteins for the treatment of an EGFR-positive malignancy, such as EGFR-positive tumors.

Abstract: The invention relates to a method for operating an internal combustion engine, in which the internal combustion engine has at least one first combustion chamber, in which combustion processes take place during fired operation of the first combustion chamber, at least one second combustion chamber, in which combustion processes take place during a fired operation of the second combustion chamber, a first knock sensor assigned to the first combustion chamber, by means of which irregular combustions in the first combustion chamber can be detected, and a second knock sensor assigned to the second combustion chamber, by means of which irregular combustions in the second combustion chamber can be detected. The internal combustion engine is operated in a first operating state in which channel switching is carried out. A switch is made from the first operating state to a second operating state in which channel switching does not take place.

Abstract: A component includes a glass or glass ceramic having a thickness and a plurality of predamages. Each predamage of the plurality of predamages has a longitudinal axis and passes continuously through the thickness of the glass or the glass ceramic. The component also includes a material compaction of the glass or glass ceramic that is at least 1% relative to an actual material density in a radius of 3 ?m about the longitudinal axis of each predamage so that the glass or the glass ceramic has a relative weight loss per predamage that is less than 10%.

Abstract: A component of glass or glass ceramic having predamages arranged along at least one predetermined dividing line is provided. The dividing line has a row of predamages lying one behind the other. The predamages pass continuously through the glass or the glass ceramic with at least 90% of the predamages being cylindrically symmetrical. The glass or the glass ceramic has a material compaction of at least 1% relative to an actual material density in a radius of 3 ?m about a longitudinal axis of respective pre-damaged points. The relative weight loss per pre-damaged point is less than 10% and the component has a thickness of at least 3.5 mm.

Abstract: A method and apparatus for producing glass products from tubular glass precursors is provided. In particular, a method and apparatus for separating tube glass into sized glass tube portions, produced glass tube portions, glass precursor portions, or glass product portions, and their use as pharmaceutical packaging are provided. The tube glass or the glass precursor or the glass product is provided with filaments along predetermined breaking planes. The filaments extend obliquely to the local wall radius and allow for clean separation of the tube glass or the glass precursor or the glass product.

Abstract: A method of processing two-dimensional substrates is provided. The method includes placing the substrate onto a substrate carrier and subjecting the substrate to a force acting towards the substrate carrier in an action zone of the substrate, but not in a compensation zone of the substrate. The substrate is predivided while being subjected to the force.

Abstract: A panel-shaped glass element is provided that includes vitreous material having a thermal expansion coefficient of less than 10×10-6 K-1 as well as two opposing surfaces. The glass element furthermore has at least one recess which runs through the glass of the glass element and has a recess wall which runs around the recess and adjoins the two opposing surfaces. The recess wall has a structure with a multiplicity of mutually adjacent rounded dome-shaped depressions. A roughness of the recess wall is formed by these depressions as well as the ridges enclosing the depressions. The recess wall has a mean roughness value (Ra) which is less than 5 µm.

Abstract: A sintered body for use as a liquid reservoir in an electronic cigarette, medication administering devices, in thermally heated evaporators for fragrant substances is provided. The sintered body is made of open-pore sintered glass and has a porosity of greater than 50 vol %. The average pore size is in a range from 1 to 450 ?m. The glass of the sintered body has a transition temperature Tg of at least 450° C.

Abstract: A component of glass or glass ceramic having predamages arranged along at least one predetermined dividing line is provided. The dividing line has a row of predamages lying one behind the other. The predamages pass continuously through the glass or the glass ceramic with at least 90% of the predamages being cylindrically symmetrical. The glass or the glass ceramic has a material compaction of at least 1% relative to an actual material density in a radius of 3 ?m about a longitudinal axis of respective pre-damaged points. The relative weight loss per pre-damaged point is less than 10% and the component has a thickness of at least 3.5 mm.

Abstract: Described are tetravalent, bispecific EGFR/CD16A antigen-binding proteins for engaging NK-cells towards EGFR-positive cells. EGFR/CD16A antigen-binding proteins with different pharmacokinetic (PK) properties are described. Further described is the use of bispecific EGFR/CD16A antigen-binding proteins for the treatment of an EGFR-positive malignancy, such as EGFR-positive tumors.

Abstract: A component of glass or glass ceramic having predamages arranged along at least one predetermined dividing line is provided. The dividing line has a row of predamages lying one behind the other. The predamages pass continuously through the glass or the glass ceramic with at least 90% of the predamages being cylindrically symmetrical. The glass or the glass ceramic has a material compaction of at least 1% relative to an actual material density in a radius of 3 ?m about a longitudinal axis of respective pre-damaged points. The relative weight loss per pre-damaged point is less than 10% and the component has a thickness of at least 3.5 mm.

Abstract: The present invention relates to a picking system for a job-related picking of goods in output bins, said picking system comprising a plurality of automated picking cells; comprising a first conveying system for the supply and/or discharge of the supply bins to and/or from the picking cells; and a second conveying system for the supply and/or discharge of the output bins to and/or from the picking cells, and a job management control for working through a plurality of picking jobs by controlling the first and second conveying systems and the plurality of picking cells, wherein at least one first picking cell has different goods handling properties than a second picking cell; and/or in that the job management control uses at least one first picking cell for working through different jobs and/or partial jobs than a second picking cell.

Abstract: Described are tetravalent, bispecific EGFR/CD16A antigen-binding proteins for engaging NK-cells towards EGFR-positive cells. EGFR/CD16A antigen-binding proteins with different pharmacokinetic (PK) properties are described. Further described is the use of bispecific EGFR/CD16A antigen-binding proteins for the treatment of an EGFR-positive malignancy, such as EGFR-positive tumors.

Abstract: A method of structuring a glass element having a first side face and a second side face is provided. The method includes the steps of: producing a filament-shaped flaw in the glass element with a pulsed laser beam along a focus line; etching to remove glass in the filament-shaped flaw to form a wall extending from the first side face towards the second side face, the wall having a boundary line that is tapered at a vertex between the wall and the first side face with a taper angle with respect to a perpendicular of the first side face; and adjusting the taper angle by controlling a feature of the focus line. The feature is selected from a group consisting of a position of the focus line, a length of the focus line, an intensity distribution of the focus line, and any combinations thereof.

Abstract: A sintered body for use as a liquid reservoir in an electronic cigarette, medication administering devices, in thermally heated evaporators for fragrant substances is provided. The sintered body is made of open-pore sintered glass and has a porosity of greater than 50 vol %. The average pore size is in a range from 1 to 450 ?m. The glass of the sintered body has a transition temperature Tg of at least 450° C.

Abstract: The present invention relates to a picking cell for a job-related automated picking of goods that can remove different goods from supply bins and can transfer them into an output bin in an automated manner, said picking cell comprising: an object detection device for detecting the goods in a supply bin; a gripper for removing the goods from a supply bin; and a cell control for evaluating the data of the object detection device and for a path planning and a control of the gripper, wherein the cell control controls the gripper such that different goods of a job or of a partial job are placed at a predefined position and/or with a predefined orientation in the output bin.

Abstract: The present invention relates to a picking system for order-related picking of goods stockpiled in racks, with an automated picking cell including a gripper for gripping and picking the goods and a cell control unit for actuating the gripper, with a transport system for conveying the racks to a picking position near the picking cell, wherein the racks have shelves and/or containers on and/or in which goods are stored, wherein at least one shelf and/or container of a rack arranged in the picking position can be conveyed from a storage position inside the rack into a removal position in which the at least one shelf and/or container is at least partially arranged in front of the rack, wherein the gripper is actuated by the cell control unit to grip the goods stockpiled on the shelf and/or in the container while the shelf and/or container is in the removal position.

Abstract: A method and device for aligning a light spot of light exiting from at least one light guide on an optical converter are provided. The device includes a light guide from which light exits and is incident on an optical converter to at least a substantial fraction, thereby forming a light spot thereon, wherein the exit surface of the fiber has an angle relative to the longitudinal axis of the fiber which is different from 0°, and the position of the light spot on the converter is aligned by adjusting the angle. A conversion module as a part of a lighting device is also provided that is operated with excitation light of a light source using a fiber-optical light guide.

Abstract: Described are tetravalent, bispecific EGFR/CD16A antigen-binding proteins for engaging NK-cells towards EGFR-positive cells. EGFR/CD16A antigen-binding proteins with different pharmacokinetic (PK) properties are described. Further described is the use of bispecific EGFR/CD16A antigen-binding proteins for the treatment of an EGFR-positive malignancy, such as EGFR-positive tumors.