Patents by Inventor Michael Kohanski

Michael Kohanski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9155792
    Abstract: The present invention is directed to the use of RecA inhibitors as antibiotic agents, and provides RecA inhibitors useful in treating infections. Also provided are various compositions and methods associated with RecA inhibition.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: October 13, 2015
    Assignee: Trustees of Boston University
    Inventors: Guillaume Cottarel, Jamey Wierzbowski, Kollol Pal, Michael Kohanski, Daniel Dwyer, James Collins, Michael Almstetter, Michael Thormann, Andreas Treml
  • Publication number: 20100029597
    Abstract: The present invention is directed to the use of RecA inhibitors as antibiotic agents, and provides RecA inhibitors useful in treating infections. Also provided are various compositions and methods associated with RecA inhibition.
    Type: Application
    Filed: February 13, 2007
    Publication date: February 4, 2010
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, PURETECH VENTURES
    Inventors: Guillaume Cottarel, Jamey Wierzbowski, Kollol Pal, Michael Kohanski, Daniel Dwyer, James Collins, Michael Almstetter, Michael Thormann, Andreas Treml
  • Publication number: 20090264342
    Abstract: The present invention provides methods for identifying target genes whose partial or complete functional inactivation potentiates the activity of an antibiotic agent, e.g., a quinolone antibiotic. The invention further provides methods for identifying agents that modulate expression of target genes or that modulate activity of expression products of target genes. Agents identified according to various methods of the invention potentiate the activity of antibiotics such as quinolones, aminoglycosides, peptide antibiotics and ?-lactams. Also provided are agents that suppress and/or retard resistance to antibiotics. The inventive methods provide potentiating agents and compositions comprising potentiating agents and antibiotics. Such agents and compositions can be used for inhibiting growth or survival of a microbial cell or of treating a subject suffering from or susceptible to a microbial infection.
    Type: Application
    Filed: February 13, 2007
    Publication date: October 22, 2009
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, PURETECH VENTURES
    Inventors: Guillaume Cottarel, Jamey Wierzbowski, Kollol Pal, Michael Kohanski, Daniel Dwyer, James Collins, Michael Almstetter, Michael Thormann, Andreas Treml