Abstract: Described herein is a production system including a unit, wherein the unit includes a subunit (1.1) for continuous manufacture of formulations. The subunit includes a combination of a small-volume process mixer and a buffer tank, means of feeding defined amounts of feedstocks into the process mixer, a measurement unit for ascertaining properties of a formulation manufactured in the process mixer, an evaluation unit for determining a deviation of properties of the formulation manufactured in the process mixer from the properties of a predefined target state, and a unit for adjusting the feed of feedstocks in view of the deviations. Also described herein is a process for manufacturing formulations.

Abstract: The present invention relates to a production system for manufacturing of formulations, comprising a unit (1). The unit (1) includes a subunit (1.1) which includes a combination of a process mixer and a buffer tank, means of feeding defined amounts of feedstocks into the process mixer, a measurement unit for ascertaining properties of a part-batch of a formulation manufactured in the process mixer, an evaluation unit for determining a deviation of properties of the part-batches manufactured in the process mixer from the properties of a predefined target state, and a unit for adjusting the feed of feedstocks in view of the deviations. The present invention also relates to a process for manufacturing formulations.

Abstract: The present invention relates to a needle (1), wherein the needle (1) comprises a channel (12) extending through the needle (1), wherein the needle (1) comprises a needle tip (11), wherein the channel (12) comprises an opening at the needle tip (11), wherein the needle (1) defines an axial direction (x), wherein the axial direction (x) defines a distal direction and a proximal direction, wherein the needle tip (11) is a distal portion of the needle (1), and wherein the needle tip (11) comprises a first surface section (112) and a second surface section (111), wherein the first surface section (112) is arranged at a first angle (?) with respect to the axial direction (x) and the second surface section (111) is arranged at a second angle (?) with respect to the axial direction (x), wherein the first angle is different from the second angle. The present invention also relates to a corresponding apparatus, system and use.

Abstract: The present invention relates to a valve assembly, comprising a valve chamber, accesses to the valve chamber, the accesses including a first access and a second access, and a movable sealing body assembly comprising at least one sealing portion, wherein at least a portion of the sealing body assembly is magnetic, and wherein at least a portion of the sealing body assembly comprising the at least one sealing portion is located within the valve chamber. Further, the valve assembly comprises at least one sealing surface, wherein each of the at least one sealing surface is configured to complement one of the at least one sealing portion, and wherein each sealing surface comprises an orifice fluidly connected to one of the accesses.

Abstract: Described herein is a modular production system for the production of formulations, the module production system including a first unit for the production of formulations and a second unit for the receipt and removal from storage of piece goods and loading units and for the provision of piece goods. Also described herein is a process for producing formulations using the modular production system.

Abstract: The present invention relates to a production system for manufacturing of formulations, comprising a unit (1). The unit (1) includes a subunit (1.1) which includes a combination of a process mixer and a buffer tank, means of feeding defined amounts of feedstocks into the process mixer, a measurement unit for ascertaining properties of a part-batch of a formulation manufactured in the process mixer, an evaluation unit for determining a deviation of properties of the part-batches manufactured in the process mixer from the properties of a predefined target state, and a unit for adjusting the feed of feedstocks in view of the deviations. The present invention also relates to a process for manufacturing formulations.

Abstract: Described herein is a production system including a unit, wherein the unit includes a subunit (1.1) for continuous manufacture of formulations. The subunit includes a combination of a small-volume process mixer and a buffer tank, means of feeding defined amounts of feedstocks into the process mixer, a measurement unit for ascertaining properties of a formulation manufactured in the process mixer, an evaluation unit for determining a deviation of properties of the formulation manufactured in the process mixer from the properties of a predefined target state, and a unit for adjusting the feed of feedstocks in view of the deviations. Also described herein is a process for manufacturing formulations.

Abstract: Described herein is a modular production system for the production of formulations, the module production system including a first unit for the production of formulations and a second unit for the receipt and removal from storage of piece goods and loading units and for the provision of piece goods. Also described herein is a process for producing formulations using the modular production system.

Abstract: To enable operation of an internal combustion engine even without the signals of a phase sensor while nonetheless enabling an emergency driving function in the case of a disturbance of a crankshaft signal acquired by a crankshaft sensor, a cylinder pressure is acquired using a cylinder pressure sensor and it is checked whether the cylinder pressure reaches a prespecifiable threshold value. When the threshold value is reached or exceeded, an angular position associated with the threshold value is inferred. The angular position is then made available for an operation of the internal combustion engine.

Abstract: To enable operation of an internal combustion engine even without the signals of a phase sensor while nonetheless enabling an emergency driving function in the case of a disturbance of a crankshaft signal acquired by a crankshaft sensor, a cylinder pressure is acquired using a cylinder pressure sensor and it is checked whether the cylinder pressure reaches a prespecifiable threshold value. When the threshold value is reached or exceeded, an angular position associated with the threshold value is inferred. The angular position is then made available for an operation of the internal combustion engine.