Patents by Inventor Michael Koob

Michael Koob has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF FULL GENE REPLACEMENT AND TRANSGENIC NON-HUMAN CELLS COMPRISING FULL HUMAN GENES
    Publication number: 20200109422
    Abstract: Provided herein are precise gene replacement methods and transgenic non-human animals produced by such methods, in which an endogenous non-human animal gene of interest is precisely replaced with a human syntenic gene. The resulting genetically modified non-human animals are useful for evaluating molecular impact of pathogenic mutations within the context of the human genomic sequence in which they occur in patients and for screening for potential therapeutic agents.
    Type: Application
    Filed: October 8, 2019
    Publication date: April 9, 2020
    Inventors: Michael Koob, Kellie Benzow
  • Transgenomic mitochondria. transmitochondrial cells and organisms, and methods of making and using
    Publication number: 20070128726
    Abstract: The invention provides transgenomic mitochondria, transmitochondrial cells and organisms, and the materials and methods for making such mitochondria, cells, and organisms.
    Type: Application
    Filed: October 16, 2006
    Publication date: June 7, 2007
    Inventors: Michael Koob, Young Yoon
  • Uncoupling element for uncoupling vibrations
    Patent number: 6324837
    Abstract: An uncoupling element is proposed for uncoupling vibrations in an exhaust gas conduit of an internal combustion engine, having a screw thread-shaped or annular waved, metal corrugated hose, which is inserted between a first conduit element arranged upstream and a second conduit element arranged downstream.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: December 4, 2001
    Assignee: Witzenmann GmbH Metallschauch-Fabik Pforzheim
    Inventors: Ekkehard Jenne, Michael Koob