Patents by Inventor Michael Koslowski

Michael Koslowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100162830
    Abstract: A torque-sensing flange, or generally a torque measurement recorder, is proposed, which has differently embodied measurement recesses or differently embodied measuring diaphragms on an essentially cylindrical measuring range. Different measuring ranges can be easily achieved in this manner.
    Type: Application
    Filed: June 14, 2007
    Publication date: July 1, 2010
    Inventors: Herbert Meuter, Michael Koslowski, Ralf Lanfermann
  • Publication number: 20100111975
    Abstract: The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing GT468, including tumor-related diseases such as breast cancer, lung cancer, gastric cancer, ovarian cancer, and hepatocellular cancer.
    Type: Application
    Filed: March 14, 2008
    Publication date: May 6, 2010
    Inventors: Ugur Sahin, Michael Koslowski, Ozlem Tureci
  • Publication number: 20090253775
    Abstract: The present invention relates to methods which make possible to assess and/or prognose a cancer disease, the metastatic behaviour of a cancer disease and/or the occurrence of a relapse of cancer. In particular, the methods of the invention make possible to assess and/or prognose the occurrence of cancer metastasis, in particular distant metastasis. Preferably, the methods of the invention allow to discriminate malign from benign conditions.
    Type: Application
    Filed: April 8, 2009
    Publication date: October 8, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Publication number: 20090221674
    Abstract: The present invention is directed to siRNA molecules which specifically target and cause RNAi-induced degradation of mRNA from TPTE genes, so that the protein product of the TPTE gene is not produced or is produced in reduced amounts. The siRNA compounds and compositions of the invention are useful for treating diseases which require inhibition of TPTE expression for their treatment, in particular cancer pathologies. The present invention also includes methods which make possible to assess and/or prognose the metastatic behaviour of a cancer disease and/or the occurrence of a relapse of cancer.
    Type: Application
    Filed: December 7, 2006
    Publication date: September 3, 2009
    Applicant: GANYMED PHARMACEUTICALS AG
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski
  • Publication number: 20090214550
    Abstract: The invention relates to identifying tumor-associated genetic products and encoding nucleic acids thereof. A therapy and diagnosis of diseases in which the tumor-associated genetic products are aberrantly expressed, proteins, polypeptides and peptides which are expressed in association with tumor and the encoding nucleic acids for said proteins, polypeptides and peptides are also disclosed.
    Type: Application
    Filed: March 23, 2006
    Publication date: August 27, 2009
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski, Gerd Helftenbein, Dirk Usener, Volker Schlüter
  • Publication number: 20090208498
    Abstract: The present technology relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the present technology also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.
    Type: Application
    Filed: April 14, 2009
    Publication date: August 20, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Publication number: 20090202530
    Abstract: The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are expressed or aberrantly expressed, in particular cancer diseases.
    Type: Application
    Filed: September 6, 2006
    Publication date: August 13, 2009
    Inventors: Ugur Sahin, Özlem Türeci, Michael Koslowski, Dirk Usener
  • Publication number: 20090155817
    Abstract: The invention relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the invention also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.
    Type: Application
    Filed: December 3, 2008
    Publication date: June 18, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Patent number: 7527933
    Abstract: The invention relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the invention also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: May 5, 2009
    Assignee: Ganymed Pharmaceuticals AG
    Inventors: Ugur Sahin, Ozlem Türeci, Michael Koslowski
  • Publication number: 20090081215
    Abstract: The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which said genetic products that are expressed in association with a tumor are expressed in an aberrant manner. The invention also relates to proteins, polypeptides, and peptides which are expressed in association with a tumor and the nucleic acids coding therefor.
    Type: Application
    Filed: August 25, 2008
    Publication date: March 26, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Publication number: 20090081214
    Abstract: The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which said genetic products that are expressed in association with a tumor are expressed in an aberrant manner. The invention also relates to proteins, polypeptides, and peptides which are expressed in association with a tumor and the nucleic acids coding therefor.
    Type: Application
    Filed: August 25, 2008
    Publication date: March 26, 2009
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Patent number: 7429461
    Abstract: The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which said genetic products that are expressed in association with a tumor are expressed in an aberrant manner. The invention also relates to proteins, polypeptides, and peptides which are expressed in association with a tumor and the nucleic acids coding therefor.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: September 30, 2008
    Assignee: Ganymed Pharmaceuticals AG
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Publication number: 20080166350
    Abstract: According to the invention, gene products expressed in a tumor-associated manner and the nucleic acids coding therefor were identified. The invention relates to the therapy and diagnosis of diseases wherein said gene products expressed in a tumor-associated manner are aberrantly expressed. The invention also relates to proteins, polypeptides and peptides which are expressed in a tumor associated manner and to nucleic acids coding therefor.
    Type: Application
    Filed: May 18, 2005
    Publication date: July 10, 2008
    Applicant: Ganymed Pharmaceuticals AG
    Inventors: Ozlem Tureci, Ugur Sahin, Michael Koslowski
  • Publication number: 20060035852
    Abstract: The invention relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for said products. Said invention also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for said polypeptides, peptides and proteins.
    Type: Application
    Filed: November 21, 2003
    Publication date: February 16, 2006
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski
  • Publication number: 20060013817
    Abstract: The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which said genetic products that are expressed in association with a tumor are expressed in an aberrant manner. The invention also relates to proteins, polypeptides, and peptides which are expressed in association with a tumor and the nucleic acids coding therefor.
    Type: Application
    Filed: March 12, 2003
    Publication date: January 19, 2006
    Inventors: Ugur Sahin, Ozlem Tureci, Michael Koslowski