Abstract: An inflatable instrument case for musical instruments includes upper and lower complementary sections, each including an inner wall and an outer wall member, forming a cavity therein between. Such cavity is inflatable. Each inner wall, of each complementary section, includes a portion thereof having an inflatable section which is independently inflatable from the cavity in each complementary section. Thus, an interior cavity is provided, surrounded by an inflatable structure, such that the inflatable structure is encapsulated within the cavities formed within the complementary sections. The exterior surface of each complementary section may be covered with a flexible material, simulating a leather-like appearance. A musical instrument may be carried within the structure, totally protected as if by floating within a column of air, and surrounded by the interior inflatable covering thereover.