Abstract: A device is provided for analyzing the coagulation and/or behavior of blood. The blood flows through an opening (9) that is disposed in a porous part (5) while a substance which influences blood aggregation can be delivered to the blood. A preliminary diffuser chamber (3) from which blood flows to the opening (9) is mounted upstream of the opening (9), and/or a secondary diffuser chamber (4) into which blood flows from the opening (9) is mounted downstream of the opening (9). The substance is arranged on the wall of the preliminary diffuser chamber (3) and/or the secondary diffuser chamber (4) in the form of a coating (8).

Abstract: A method for investigating the thrombocyte function of the blood, and particularly of platelet aggregation, wherein the following steps are carried out: a) cross-flowing an aperture with blood or blood components; b) determining the active radius of the aperture depending on time and c) evaluating the time-dependent modification of the radius as a measure for blood cell and/or thrombocyte function.

Abstract: A device for automatically analyzing blood samples includes an extraction station (I), where blood can be extracted from a storage vessel (40) by an extraction device (15); a measuring station (II), where the extracted blood can be passed via a head part (46) through an aperture (26) of an aperture holder (30) arranged in a measuring part (9), the measuring part (9) being connected to the head part (46); a receiving station (III), for receiving measuring parts (9) configured as disposable parts; and a device (3) for moving the extraction device (15) and the head part (46) between the extraction station (I), the measuring station (II) and the receiving station (III).

Abstract: A method for investigating the thrombocyte function of the blood, and particularly of platelet aggregation, wherein the following steps are carried out: a) cross-flowing an aperture with blood or blood components; b) determining the active radius of the aperture depending on time and c) evaluating the time-dependent modification of the radius as a measure for blood cell and/or thrombocyte function.

Abstract: The invention relates to a throughflow device for measuring platelet function of primary hemostasis, aggregation and/or coagulation and/or viscosity of the blood. A reservoir (8), from which blood can be taken for measurement and transported through an aperture (7), is arranged in a housing (2). A stirring device (10,11,12,13) is provided in the reservoir (8) and can be moved in such a way that a stirrer part (11) of the stirring device (10,11,12,13) mixes the blood which is located in the storage chamber (8) during measurement and maintains it in a state of motion.

Abstract: A device for automatically analyzing blood samples includes an extraction station (I), where blood can be extracted from a storage vessel (40) by means of an extraction device (15); a measuring station (II), where the extracted blood can be passed via a head part (46) through an aperture (26) of an aperture holder (30) arranged in a measuring part (9), the measuring part (9) being connected to the head part (46); a receiving station (III), where the measuring parts (9) configured as disposable parts are provided and can be connected to the head part (46) and a device (3) for moving the extraction device (15) and the head part (46) between the extraction station (I), the measuring station (II) and the receiving station (III).

Abstract: The invention relates to a throughflow device for measuring platelet function of primary hemostasis, aggregation and/or coagulation and/or viscosity of the blood. A reservoir (8), from which blood can be taken for measurement and transported through an aperture (7), is arranged in a housing (2). A stirring device (10,11,12,13) is provided in the reservoir (8) and can be moved in such a way that a stirrer part (11) of the stirring device (10,11,12,13) mixes the blood which is located in the storage chamber (8) during measurement and maintains it in a state of motion.

Abstract: A device is provided for analyzing the coagulation and/or behavior of blood. The blood flows through an opening (9) that is disposed in a porous part (5) while a substance which influences blood aggregation can be delivered to the blood. A preliminary diffuser chamber (3) from which blood flows to the opening (9) is mounted upstream of the opening (9), and/or a secondary diffuser chamber (4) into which blood flows from the opening (9) is mounted downstream of the opening (9). The substance is arranged on the wall of the preliminary diffuser chamber (3) and/or the secondary diffuser chamber (4) in the form of a coating (8).

Abstract: The invention relates to a method for investigating the thrombocyte function of the blood, wherein the following steps are carried out: a) cross-flowing an aperture (3) with blood or blood components; b) determining the active radius of the aperture (3) depending on time and c) evaluating the time-dependent modification of the radius as a measure for blood cell and/or thrombocyte function.

Abstract: A process and device are disclosed for measuring blood platelet aggregation or blood coagulation. The blood flows through an opening in a part and the occlusion of the opening is measured. The pressure fall (.DELTA.P) formed during occlusion of the opening is measured at predetermined time intervals (dt) and the volume flow (I) is changed to correspond to a predetermined function which simulates the flow resistance (R.sub.v) of a capillary upstream of the opening. Alternatively, the pressure (.DELTA.P) is kept constant during the predetermined time intervals (dt) and afterwards, when the volume flow (I) has diminished by a certain value, the pressure is adjusted until it corresponds to the function.

Abstract: A robotic gripper, the grippers of which engage as positive-fit elements on a magazine wall. The gripper is used to grip magazines for lead frames. This prevents any pressure stress on the magazines. The positive-fit elements furthermore, because of their shape, prevent the lead frames from slipping out of the magazine under high accelerations.

Abstract: A measuring unit for performing plural bleeding time analyses has a vessel divided into at least two chambers by a separating wall. Each chamber has a capillary coupled to an outlet in the chamber base wall, and the outlet is also in communication with an aperture of an apertured filter unit placed adjacent the base wall.

Abstract: The invention pertains to a device for the automatic examination of blood samples with one test station, in which blood is taken from a supply vessel and is fed through an aperture in a part held in an aperture holder. At least one test head is provided, to which is fed from a first magazine holder, supply vessels with blood, and from a second magazine holder, aperture holders are fed. After performance of at least one measurement on one aperture holder, the used aperture holder and the used supply vessel are removed from the test head and the test head is cleaned by a cleaning device.

Abstract: The invention pertains to a device for the safe removal of blood from a supply vessel with an aperture holder in which a part having an aperture is held and to which a capillary is attached, whereby the supply vessel can be closed by a cover part. The cover part a region through which the capillary can be inserted into the supply vessel when the cover part is closed. Furthermore, the supply vessel and the aperture holder have a locking mechanism, so that the supply vessel can be locked to the aperture holder.

Abstract: The invention relates to a device for examining the functions of the endothelium or the intima of blood vessels. A tube (1) has at least one outlet (6) and at least one inlet (7) spaced along the wall thereof. Outlet (6) communicates with a connector (8), inlet (7) communicates with another connector (9). Connectors (8, 9) are provided in tube (1) at the end thereof projecting from blood vessel (4).

Abstract: Apparatus for selective destruction or inactivation of cells is disclosed wherein cells are arrayed in a plane for successive illumination, by optical X-Y scanning devices, with a first low powered light beam to produce in particular cells certain radiations responsive to the illumination. These response radiations are detected and used to enable a second higher powered light beam directed through substantially the same optical scanning paths, to destroy or inactivate the cells producing the response radiations. The illumination, response, detection, and high power radiation steps are accomplished by devices acting in times short as compared to the X-Y scanning devices so as to make the accurate treatment of each of large numbers of cells highly effective.

Abstract: Apparatus for selective destruction or inactivation of cells is disclosed wherein cells are arrayed in a plane for successive illumination, by optical X-Y scanning devices, with a first low power red light beam to produce in particular cells certain radiations responsive to the illumination. These response radiations are detected and used to enable a second higher powered light beam directed through substantially the same optical scanning paths, to destroy or inactivate the cells producing the response radiations. The illumination, response, detection, and high power radiation steps are accomplished by devices acting in times short as compared to the X-Y scanning devices so as to make the accurate treatment of each of large numbers of cells highly effective.

Abstract: A method and apparatus are disclosed for measuring the aggregation of blood platelets or the coagulation of blood, the apparatus including a capillary tube for drawing blood, a piston in communication with the capillary tube and connected to a motor means for linear displacement thereof, a pressure sensor in the space located between the drawn blood and piston, and a computing means or microprocessing means for comparing the sensed pressure from the pressure sensor with a predetermined value, and providing a measured regulating output to the motor means. The method for measuring the aggregation of blood platelets and coagulation of blood includes the steps of drawing blood into the capillary tube of the moveable piston until the desired pressure is achieved within the capillary tube, and allowing the computing means to then maintain by adjustment of the piston position the pressure within the capillary tube.

Abstract: A system for measuring bleeding time in vitro is disclosed in which blood is passed under pressure through a porous element and the resulting volumetric flow is measured. The porous element is provided with a through aperture and supported in such a manner that the blood moves through the aperture and not laterally into the porous element. The porous element can be soaked in a solution, for example, adenosine diphosphate, which coagulates the platelets and in this manner it is possible to reproduce in vivo bleeding conditions.