Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: A shading display and sample may include a frame structure, a drive assembly operably connected to the frame structure, and a shade material associated with the drive assembly for corresponding movement thereof. Operation of the drive assembly may move the shade material between open and closed positions. The display may permit users to position and operate a covering sample near an architectural opening to assess the overall operation, appearance, translucence, texture, or other qualities of the covering based on the angular orientation and material of the sample.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: A bicycle and bicycle parking and lock system wherein a hub locking device that is secured to a bicycle cooperates with a parking rack. The bicycle includes an engagement member that is secured to an axle of the bicycle. The engagement member selectively removably cooperates with a recess formed in the parking and lock system. The parking and lock system includes a number of upstanding members that are positioned to generally flank the front wheel of a bicycle to maintain the bicycle in a generally upright orientation. Each or select number of the upstanding members include a lock system that cooperates with the locking engagement member so as to secure the respective bicycle with respect to the parking system.

Abstract: A bicycle and bicycle parking and lock system wherein a hub locking device that is secured to a bicycle cooperates with a parking rack. The bicycle includes an engagement member that is secured to an axle of the bicycle. The engagement member selectively removably cooperates with a recess formed in the parking and lock system. The parking and lock system includes a number of upstanding members that are positioned to generally flank the front wheel of a bicycle to maintain the bicycle in a generally upright orientation. Each or select number of the upstanding members include a lock system that cooperates with the locking engagement member so as to secure the respective bicycle with respect to the parking system.

Abstract: A shading display and sample is provided. The display may include a frame structure, a drive assembly operably connected to the frame structure, and a shade material associated with the drive assembly for corresponding movement thereof. Operation of the drive assembly may move the shade material between open and closed positions. The display may permit users to position and operate a covering sample near an architectural opening to assess the overall operation, appearance, translucence, texture, or other qualities of the covering based on the angular orientation and material of the sample.

Abstract: A bicycle and bicycle parking and lock system wherein a hub locking device that is secured to a bicycle cooperates with a parking rack. The bicycle includes an engagement member that is secured to an axle of the bicycle. The engagement member selectively removably cooperates with a recess formed in the parking and lock system. The parking and lock system includes a number of upstanding members that are positioned to generally flank the front wheel of a bicycle to maintain the bicycle in a generally upright orientation. Each or select number of the upstanding members include a lock system that cooperates with the locking engagement member so as to secure the respective bicycle with respect to the parking system.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: A bicycle and bicycle parking and lock system wherein a hub locking device that is secured to a bicycle cooperates with a parking rack. The bicycle includes an engagement member that is secured to an axle of the bicycle. The engagement member selectively removably cooperates with a recess formed in the parking and lock system. The parking and lock system includes a number of upstanding members that are positioned to generally flank the front wheel of a bicycle to maintain the bicycle in a generally upright orientation. Each or select number of the upstanding members include a lock system that cooperates with the locking engagement member so as to secure the respective bicycle with respect to the parking system.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAP?, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAP? binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.

Abstract: A bicycle and bicycle parking and lock system wherein a hub locking device that is secured to a bicycle cooperates with a parking rack. The bicycle includes an engagement member that is secured to an axle of the bicycle. The engagement member selectively removably cooperates with a recess formed in the parking and lock system. The parking and lock system includes a number of upstanding members that are positioned to generally flank the front wheel of a bicycle to maintain the bicycle in a generally upright orientation. Each or select number of the upstanding members include a lock system that cooperates with the locking engagement member so as to secure the respective bicycle with respect to the parking system.

Abstract: A bicycle and bicycle parking and lock system wherein a hub locking device that is secured to a bicycle cooperates with a parking rack. The bicycle includes an engagement member that is secured to an axle of the bicycle. The engagement member selectively removably cooperates with a recess formed in the parking and lock system. The parking and lock system includes a number of upstanding members that are positioned to generally flank the front wheel of a bicycle to maintain the bicycle in a generally upright orientation. Each or select number of the upstanding members include a lock system that cooperates with the locking engagement member so as to secure the respective bicycle with respect to the parking system.