Patents by Inventor Michael Kurman

Michael Kurman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active taxane analogs and methods of treatment by oral administration
    Patent number: 11873308
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Grant
    Filed: December 1, 2021
    Date of Patent: January 16, 2024
    Assignee: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Taxane analogs for the treatment of brain cancer
    Patent number: 11786504
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: October 17, 2023
    Assignee: TAPESTRY PHARMACEUTICALS, INC.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Biologically Active Taxane Analogs and Methods of Treatment by Oral Administration
    Publication number: 20220089606
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Application
    Filed: December 1, 2021
    Publication date: March 24, 2022
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Biologically active taxane analogs and methods of treatment by oral administration
    Patent number: 11220512
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: January 11, 2022
    Assignee: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Taxane Analogs for the Treatment of Brain Cancer
    Publication number: 20210401797
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Application
    Filed: September 9, 2021
    Publication date: December 30, 2021
    Applicant: TAPESTRY PHARMACEUTICALS, INC.
    Inventors: James D. MCCHESNEY, Gilles H. TAPOLSKY, David L. EMERSON, John MARSHALL, Michael KURMAN, Manuel MODIANO
  • Taxane analogs for the treatment of brain cancer
    Patent number: 11147793
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubules at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: October 19, 2021
    Assignee: TAPESTRY PHARMACEUTICALS, INC.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Biologically Active Taxane Analogs and Methods of Treatment by Oral Administration
    Publication number: 20200347076
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Application
    Filed: July 15, 2020
    Publication date: November 5, 2020
    Inventors: James D. McChesney, Gilles H. Tapolsky, David LLoyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Biologically active taxane analogs and methods of treatment by oral administration
    Patent number: 10745408
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: August 18, 2020
    Assignee: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Biologically Active Taxane Analogs and Methods of Treatment by Oral Administration
    Publication number: 20200002351
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Application
    Filed: September 12, 2019
    Publication date: January 2, 2020
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Biologically active taxane analogs and methods of treatment by oral administration
    Patent number: 10450323
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: October 22, 2019
    Assignee: TAPESTRY PHARMACEUTICALS, INC.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Taxane Analogs for the Treatment of Brain Cancer
    Publication number: 20190046501
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubules at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Application
    Filed: October 12, 2018
    Publication date: February 14, 2019
    Applicant: TAPESTRY PHARMACEUTICALS, INC.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Taxane analogs for the treatment of brain cancer
    Patent number: 10143677
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: December 4, 2018
    Assignee: TAPESTRY PHARMACEUTICALS, INC.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Taxane Analogs for the Treatment of Brain Cancer
    Publication number: 20180117002
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Application
    Filed: April 10, 2017
    Publication date: May 3, 2018
    Applicant: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Biologically Active Taxane Analogs and Methods of Treatment by Oral Administration
    Publication number: 20180105535
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Application
    Filed: October 30, 2017
    Publication date: April 19, 2018
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Biologically active taxane analogs and methods of treatment by oral administration
    Patent number: 9802951
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: October 31, 2017
    Assignee: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Michael Kurman, Manuel R. Modiano
  • Taxane Analogs for the Treatment of Brain Cancer
    Publication number: 20170273942
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Application
    Filed: April 10, 2017
    Publication date: September 28, 2017
    Applicant: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles H. Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Taxane analogs for the treatment of brain cancer
    Patent number: 9616043
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: April 11, 2017
    Assignee: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • TAXANE ANALOGS FOR THE TREATMENT OF BRAIN CANCER
    Publication number: 20160113898
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Application
    Filed: September 11, 2015
    Publication date: April 28, 2016
    Applicant: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Taxane analogs for the treatment of brain cancer
    Patent number: 9132118
    Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: September 15, 2015
    Assignee: Tapestry Pharmaceuticals, Inc.
    Inventors: James D. McChesney, Gilles Tapolsky, David L. Emerson, John Marshall, Michael Kurman, Manuel Modiano
  • Biologically Active Taxane Analogs and Methods of Treatment by Oral Administration
    Publication number: 20140023699
    Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.
    Type: Application
    Filed: July 25, 2013
    Publication date: January 23, 2014
    Inventors: James D. McChesney, Gilles H. Tapolsky, David Lloyd Emerson, John Marshall, Tauseef Ahmed, Allen Cohn, Michael Kurman, Manuel R. Modiano