Abstract: An imaging apparatus is provided to facilitate epifluorescent imaging of three (or more) color channels and to perform phase contrast and/or bright field imaging of samples without manual adjustment of the imaging apparatus. This allows for automated imaging, over extended periods of time, of a plurality of samples by a device located inside an incubator without disturbing the incubator environment to manually adjust the apparatus. Also provided are embodiments to facilitate user swapping of removable optical modules and/or transillumination modules to allow the imaging apparatus to be adapted to different combinations of assays and/or fluorescent indicators so as to increase the variety of experiments and/or fluorescent dyes that can be imaged using the imaging apparatus.

Abstract: An imaging apparatus is provided to facilitate epifluorescent imaging of three (or more) color channels and to perform phase contrast and/or bright field imaging of samples without manual adjustment of the imaging apparatus. This allows for automated imaging, over extended periods of time, of a plurality of samples by a device located inside an incubator without disturbing the incubator environment to manually adjust the apparatus. Also provided are embodiments to facilitate user swapping of removable optical modules and/or transillumination modules to allow the imaging apparatus to be adapted to different combinations of assays and/or fluorescent indicators so as to increase the variety of experiments and/or fluorescent dyes that can be imaged using the imaging apparatus.

Abstract: A method of assembling a scintillation detector including placing a scintillator crystal in a casing, and forming a sealed casing having a controlled atmosphere different than ambient atmosphere, wherein the controlled atmosphere includes an inert gas and a trace gas in an amount of at least about 1 vol % and not greater than about 30 vol %, wherein the trace gas is selected from the group of materials consisting of hydrogen, helium, neon, krypton, xenon, and carbon monoxide. The assembling method further includes testing the sealed casing for leaks by detecting the presence of the trace gas.

Abstract: A system for performing medical imaging in a mobile environment. The system includes a sensing array, a controller, and a mobile frame. The sensing array is configured to image a subject. The controller is in communication with the sensing array to control and process the acquisition performed by the sensing array. The sensing array is attached to the mobile frame, and the mobile frame includes wheels to facilitate movement of the system. At least one of the wheels of the base interacts with a wheel lock, such that the wheel lock prevents motion of the wheel when activated by the controller.

Abstract: A method of assembling a scintillation detector including placing a scintillator crystal in a casing, and forming a sealed casing having a controlled atmosphere different than ambient atmosphere, wherein the controlled atmosphere includes an inert gas and a trace gas in an amount of at least about 1 vol % and not greater than about 30 vol %, wherein the trace gas is selected from the group of materials consisting of hydrogen, helium, neon, krypton, xenon, and carbon monoxide. The assembling method further includes testing the sealed casing for leaks by detecting the presence of the trace gas.