Patents by Inventor Michael L Brines

Michael L Brines has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and composition for rejuvenating hair, nails, tissues, cells and organs by ex-vivo or immersive treatment
    Patent number: 7384625
    Abstract: A method and composition for the treatment of hair, nail, ex-vivo organ, ex-vivo cell or ex-vivo tissue to improve the biomechanical and diffusional characteristics comprising an effective amount of a compound selected from the group consisting of compounds of the formula (I):
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: June 10, 2008
    Assignee: Farington Pharmaceuticals, LLC
    Inventors: Michael L. Brines, Anthony Cerami
  • Sustained release delivery systems for solutes
    Patent number: 7090861
    Abstract: The present invention relates to devices that allow for linear, sustained-release of solutes with adjustable initial-release kinetics. In particular, the present invention relates to devices for delivering substances to the body of an animal. The present invention also relates to methods for delivering solutes in a constant, sustained-release fashion using the devices of the invention.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: August 15, 2006
    Assignee: Farrington Pharmaceuticals, LLC
    Inventors: Michael L. Brines, Anthony Cerami, Jean-Paul Wuerth
  • Method and composition for rejuvenating cells, tissues, organs, hair and nails
    Patent number: 7022721
    Abstract: In one embodiment, the present invention relates to compounds and compositions including pharmaceutical compositions containing the compounds and associated methods that uncouple sugar-mediated coupling of proteins, lipids, nucleic acids, and other biomaterials, and any combination thereof. In another embodiment, the compositions and associated methods have utility in vivo to reduce the deleterious effects of sugar-mediated coupling processes in an organism, when the organism is exposed to the compound or composition internally, by ingestion, transdermal application, or other means. In yet another embodiment, the compositions and associated methods are useful for the ex-vivo treatment of organs, cells and tissues and external treatment of hair, nails and skin to rejuvenate them by changing deformability and increase the tissue diffusion coefficient. In a further embodiment, the present invention relates to novel compounds and pharmaceutical compositions.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: April 4, 2006
    Inventors: Peter C Ulrich, Sheng Ding Fang, Michael L Brines, Qiao-Wen Xie, Anthony Cerami
  • Method and composition for rejuvenating cells, tissues organs, hair and nails
    Patent number: 6777557
    Abstract: In one embodiment, the present invention relates to compounds and compositions including pharmaceutical compositions containing the compounds and associated methods that uncouple sugar-mediated coupling of proteins, lipids, nucleic acids, and other biomaterials, and any combination thereof. In another embodiment, the compositions and associated methods have utility in vivo to reduce the deleterious effects of sugar-mediated coupling processes in an organism, when the organism is exposed to the compound or composition internally, by ingestion, transdermal application, or other means. In yet another embodiment, the compositions and associated methods are useful for the ex-vivo treatment of organs, cells and tissues and external treatment of hair, nails and skin to rejuvenate them by changing deformability and increase the tissue diffusion coefficient. In a further embodiment, the present invention relates to novel compounds and pharmaceutical compositions.
    Type: Grant
    Filed: February 7, 2002
    Date of Patent: August 17, 2004
    Inventors: Peter C Ulrich, Sheng Ding Fang, Michael L Brines, Qiao-Wen Xie, Anthony Cerami
  • Method and composition for rejuvenating hair, nails, tissues, cells and organs by ex-vivo or immersive treatment
    Publication number: 20030185776
    Abstract: A method and composition for the treatment of hair, nail, ex-vivo organ, ex-vivo cell or ex-vivo tissue to improve the biomechanical and diffusional characteristics comprising an effective amount of a compound selected from the group consisting of compounds of the formula (I): 1
    Type: Application
    Filed: March 18, 2003
    Publication date: October 2, 2003
    Inventors: Michael L. Brines, Anthony Cerami
  • Sustained release delivery systems for solutes
    Publication number: 20030176853
    Abstract: The present invention relates to devices that allow for linear, sustained-release of solutes with adjustable initial-release kinetics. In particular, the present invention relates to devices for delivering substances to the body of an animal. The present invention also relates to methods for delivering solutes in a constant, sustained-release fashion using the devices of the invention.
    Type: Application
    Filed: March 19, 2003
    Publication date: September 18, 2003
    Inventors: Michael L. Brines, Anthony Cerami, Jean-Paul Wuerth
  • Method and composition for rejuvinating cells, tissues organs, hair and nails
    Publication number: 20020188015
    Abstract: In one embodiment, the present invention relates to compounds and compositions including pharmaceutical compositions containing the compounds and associated methods that uncouple sugar-mediated coupling of proteins, lipids, nucleic acids, and other biomaterials, and any combination thereof. In another embodiment, the compositions and associated methods have utility in vivo to reduce the deleterious effects of sugar-mediated coupling processes in an organism, when the organism is exposed to the compound or composition internally, by ingestion, transdermal application, or other means. In yet another embodiment, the compositions and associated methods are useful for the ex-vivo treatment of organs, cells and tissues and external treatment of hair, nails and skin to rejuvenate them by changing deformability and increase the tissue diffusion coefficient. In a further embodiment, the present invention relates to novel compounds and pharmaceutical compositions.
    Type: Application
    Filed: February 7, 2002
    Publication date: December 12, 2002
    Inventors: Peter C. Ulrich, Sheng Ding Fang, Michael L. Brines, Qiao-Wen Xie, Anthony Cerami
  • Method and composition for rejuvenating hair, nails, tissues, cells and organs by ex-vivo or immersive treatment
    Publication number: 20020182165
    Abstract: A method and composition for the treatment of hair, nail, ex-vivo organ, ex-vivo cell or ex-vivo tissue to improve the biomechanical and diffusional characteristics comprising an effective amount of a compound selected from the group consisting of compounds of the formula 1
    Type: Application
    Filed: January 22, 2002
    Publication date: December 5, 2002
    Inventors: Michael L. Brines, Anthony Cerami