Patents by Inventor Michael L. Bukrinsky

Michael L. Bukrinsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods of use to treat infectious diseases
    Publication number: 20020077271
    Abstract: The present invention concerns alkyl aryl carbonyl compounds that possess anti-infective activity. The compounds of the invention can be used to target specific nuclear localization signal, thereby blocking importation of specific proteins or molecular complex into the nucleus of a cell. The invention encompasses methods of use of such compounds for treatment or prevention of infectious diseases, such as parasitic and viral diseases, including, for example, malaria and acquired immunodeficiency syndrome. The use of the compounds to detect certain specific protein structures which are present in nuclear localization sequences is also taught.
    Type: Application
    Filed: June 25, 2001
    Publication date: June 20, 2002
    Inventors: Anthony Cerami, Peter Ulrich, Michael L. Bukrinsky
  • Compounds and methods of use to treat infectious diseases
    Patent number: 6297253
    Abstract: The present invention concerns alkyl aryl carbonyl compounds that possess anti-infective activity. The compounds of the invention can be used to target specific nuclear localization signal, thereby blocking importation of specific proteins or molecular complex into the nucleus of a cell. The invention encompasses methods of use of such compounds for treatment or prevention of infectious diseases, such as parasitic and viral diseases, including, for example, malaria and acquired immunodeficiency syndrome. The use of the compounds to detect certain specific protein structures which are present in nuclear localization sequences is also taught.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: October 2, 2001
    Assignee: The Picower Institute For Medical Research
    Inventors: Michael L. Bukrinsky, Anthony Cerami, Peter Ulrich