Patents by Inventor Michael Löffler

Michael Löffler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11932061
    Abstract: An electronic wheel unit for arrangement on a vehicle wheel of a vehicle, having at least one sensor for detecting at least one wheel operational parameter, a control device, which is designed to generate wheel operational data on the basis of the at least one wheel operational parameter, a radio device for transmitting radio data signals containing the wheel operational data, a power supply device for supplying electrical power to the wheel unit which has an energy-harvesting device for converting mechanical energy captured on a rotation of the vehicle wheel into electrical energy and an electric battery, wherein the electronic wheel unit furthermore has a switchover device for switching over between the energy-harvesting device, and the electric battery for the electrical power supply to the wheel unit, and the switchover device has an actuable switch and an actuating device for actuating the switch, wherein the at least one wheel operational parameter comprises an acceleration parameter, and the actuating
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: March 19, 2024
    Assignee: Continental Automotive Technologies GmbH
    Inventor: Michael Löffler
  • Publication number: 20230399672
    Abstract: The present invention in various aspects and embodiments provides engineered bacterial strains having a modified genome that provides advantages in maintenance and biosynthetic processes when cultured at large scale. The present invention further provides methods for large-scale fermentation using the bacterial strains. In various embodiments, the strain engineering yields a reduction in cellular responses to micro-environmental stimuli imposed in large scale bioreactors.
    Type: Application
    Filed: November 2, 2021
    Publication date: December 14, 2023
    Inventors: Martin ZIEGLER, Ralf TAKORS, Joana SIEMEN, Michael LÖFFLER, Christine Nicole S. SANTOS, Ajikumar Parayil KUMARAN
  • Publication number: 20230079930
    Abstract: An electronic wheel unit for arrangement on a vehicle wheel of a vehicle, having at least one sensor for detecting at least one wheel operational parameter, a control device, which is designed to generate wheel operational data on the basis of the at least one wheel operational parameter, a radio device for transmitting radio data signals containing the wheel operational data, a power supply device for supplying electrical power to the wheel unit which has an energy-harvesting device for converting mechanical energy captured on a rotation of the vehicle wheel into electrical energy and an electric battery, wherein the electronic wheel unit furthermore has a switchover device for switching over between the energy-harvesting device, and the electric battery for the electrical power supply to the wheel unit, and the switchover device has an actuable switch and an actuating device for actuating the switch, wherein the at least one wheel operational parameter comprises an acceleration parameter, and the actuating
    Type: Application
    Filed: December 4, 2020
    Publication date: March 16, 2023
    Applicant: Continental Automotive Technologies GmbH
    Inventor: Michael Löffler
  • Publication number: 20230065157
    Abstract: The invention relates to a method for identifying electronic wheel units (12-1 to 12-6b) arranged on vehicle wheels (W1-W6b) of a vehicle (1), by means of which method those electronic wheel units (12-3a, 12-3b; 12-4a, 12-4b; 12-5a, 12-5b; 12-6a, 12-6b) which are arranged on vehicle wheels (W3a, W3b; W4a, W4b; W5a, W5b; W6a, W6b) connected to one another for conjoint rotation are identified, the method comprising the steps of: acquiring a respective cumulative number (Ni) of revolutions of each of the vehicle wheels (W1-W6b) using the electronic wheel units (12-1 to 12-6b); comparing with one another the cumulative numbers (Ni) of revolutions of the vehicle wheels (W1-W6b), identifying those electronic wheel units (12-3a, 12-3b; 12-4a, 12-4b; 12-5a, 12-5b, 12-6a, 12-6b) for which the cumulative numbers (Ni) of revolutions at least approximately coincide as being arranged connected to one another for conjoint rotation.
    Type: Application
    Filed: February 9, 2021
    Publication date: March 2, 2023
    Applicant: Continental Automotive Technologies GmbH
    Inventor: Michael Löffler
  • Patent number: 11358419
    Abstract: A method for detecting wheel units mounted at wheels of a vehicle and for detecting wheel mounting positions belonging to each of the wheel units is disclosed. The method comprises the steps of: positioning a mobile communication device at a predetermined start position with respect to the vehicle, moving the mobile communication device from the start position along a path around the vehicle, receiving RF signals from the wheel units and measuring the RF signal strengths thereof by the mobile communication device when moving along the path around the vehicle, performing an analysis of variations of the measured RF signal strengths of the received RF signals depending on the position of the mobile communication device along the path, identifying the wheel units and identifying the wheel mounting positions based on a result of the analysis.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: June 14, 2022
    Assignee: Continental Automotive GmbH
    Inventors: Matthias Kretschmann, Parthiv Dharamshi, Michael Löffler, Jean-Philippe Boisset
  • Patent number: 11325433
    Abstract: A method for reconfiguring a device for monitoring a tire, incorporating a pressure sensor and a communication module. The device may receive and store configuration data intrinsic to the tire. Based on pressure measurements and the configuration data, the device generates and stores advanced data relating to use of the tire over time. Following reception of new configuration data, the method includes: detecting a tire change based on the previously stored configuration data and the newly received configuration data, if a tire change is detected: erasing the advanced data from the memory means of the device, if not, retaining the advanced data in the memory of the device.
    Type: Grant
    Filed: May 27, 2019
    Date of Patent: May 10, 2022
    Assignees: CONTINENTAL AUTOMOTIVE FRANCE, CONTINENTAL AUTOMOTIVE GMBH
    Inventors: Davy Ribreau, Jean-Philippe Boisset, Michael Löffler
  • Patent number: 11230146
    Abstract: A method for determining a tread depth of a tread of a tire during operation of a vehicle comprising the tire, a controller for a vehicle for determining a tread depth of a tread of a tire of the vehicle, and a system for a vehicle, comprising such a controller and at least one electronic wheel unit, wherein there is provision to determine the tread depth based on a determined instantaneous dynamic wheel radius of a wheel, comprising the tire, of the vehicle and a determined instantaneous dynamic inside radius of the tire are disclosed. To improve the accuracy of determination of the tread depth a correction variable predetermined for the type of tire is taken into consideration, which correction variable characterizes the relationship between a change in the tread depth, and a change resulting therefrom in the difference between the dynamic wheel radius and the dynamic inside radius.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: January 25, 2022
    Inventors: Alexander Kuerzl, Matthias Kretschmann, Michael Löffler
  • Publication number: 20210268849
    Abstract: A method for detecting wheel units mounted at wheels of a vehicle and for detecting wheel mounting positions belonging to each of the wheel units is disclosed. The method comprises the steps of: positioning a mobile communication device at a predetermined start position with respect to the vehicle moving the mobile communication device from the start position along a path around the vehicle receiving RF signals from the wheel units and measuring the RF signal strengths thereof by the mobile communication device when moving along the path around the vehicle performing an analysis of variations of the measured RF signal strengths of the received RF signals depending on the position of the mobile communication device along the path identifying the wheel units and identifying the wheel mounting positions based on a result of the analysis.
    Type: Application
    Filed: June 18, 2019
    Publication date: September 2, 2021
    Inventors: Matthias Kretschmann, Parthiv Dharamshi, Michael Löffler, Jean-Philippe Boisset
  • Publication number: 20210268851
    Abstract: Disclosed are a method and a system for detecting a faulty arrangement of a sensor module in a sensor module holder in a tire of a vehicle equipped with a tire monitoring system. The detection of a faulty arrangement of a sensor module may be performed by ascertaining on the basis of a comparison of the operating parameters determined by the sensor modules of the tire monitoring system that there is for this sensor module a discrepancy, dependent on a speed of the vehicle, between the operating parameter and an operating parameter to be expected for this sensor module.
    Type: Application
    Filed: July 3, 2019
    Publication date: September 2, 2021
    Inventors: Parthiv Dharamshi, Matthias Kretschmann, Shichao You, Michael Löffler
  • Publication number: 20210206211
    Abstract: A method for reconfiguring a device for monitoring a tire, incorporating a pressure sensor and a communication module. The device may receive and store configuration data intrinsic to the tire. Based on pressure measurements and the configuration data, the device generates and stores advanced data relating to use of the tire over time. Following reception of new configuration data, the method includes: detecting a tire change based on the previously stored configuration data and the newly received configuration data, if a tire change is detected: erasing the advanced data from the memory means of the device, if not, retaining the advanced data in the memory of the device.
    Type: Application
    Filed: May 27, 2019
    Publication date: July 8, 2021
    Inventors: Davy Ribreau, Jean-Philippe Boisset, Michael Löffler
  • Publication number: 20200070589
    Abstract: A method for determining a tread depth of a tread of a tire during operation of a vehicle comprising the tire, a controller for a vehicle for determining a tread depth of a tread of a tire of the vehicle, and a system for a vehicle, comprising such a controller and at least one electronic wheel unit, wherein there is provision to determine the tread depth based on a determined instantaneous dynamic wheel radius of a wheel, comprising the tire, of the vehicle and a determined instantaneous dynamic inside radius of the tire are disclosed. To improve the accuracy of determination of the tread depth a correction variable predetermined for the type of tire is taken into consideration, which correction variable characterizes the relationship between a change in the tread depth, and a change resulting therefrom in the difference between the dynamic wheel radius and the dynamic inside radius.
    Type: Application
    Filed: March 20, 2018
    Publication date: March 5, 2020
    Inventors: Alexander Kuerzl, Matthias Kretschmann, Michael Löffler
  • Publication number: 20100162994
    Abstract: The present invention relates to a valve device (13) for controlling a gas flow in a fresh air system (6) of an internal combustion engine (2), in particular of a motor vehicle, with a housing (17) which encloses at least one duct section (19) through which the gas flow (14) can pass transversely to the main flow direction (18), with at least one flap (15) which can be rotated about an axis of rotation (21) which runs transversely with respect to the main flow direction (18) in the duct section (19). In order to improve the fail-safety of the valve device (13), at least one rotary frame (24) is provided, which can be rotated about an axis of rotation (25) which runs transversely with respect to the main flow direction (18) in the duct section (19) and has a frame opening (26) through which the gas flow (14) can pass.
    Type: Application
    Filed: December 17, 2009
    Publication date: July 1, 2010
    Inventors: Alfred Elsäßer, Patric Genieser, Dietmar Türpe, Michael Löffler
  • Publication number: 20060048538
    Abstract: A sorptive heat exchanger (E), which presents a plurality of heat exchange channels (10) in thermal contact with respective sorption channels (11), where sorption material (12) is fixed on the internal surfaces of channels (11).
    Type: Application
    Filed: May 9, 2003
    Publication date: March 9, 2006
    Inventors: Michael Loffler, Hans Henning
  • Patent number: 6133442
    Abstract: Compounds of formula I ##STR1## wherein R.sup.1 signifies phenyl, substituted phenyl or heterocyclyl;R.sup.2 signifies phenyl or substituted phenyl;R.sup.3 signifies hydrogen, lower-alkyl, cyano, carboxy, esterified carboxy, phenyl, substituted phenyl, heterocyclyl or a residue --CONR.sup.5 R.sup.6 or --NR.sup.5 COR.sup.7 ;R.sup.4 signifies hydrogen or lower-alkyl;R.sup.5 signifies hydrogen or a residue R.sup.7, andR.sup.6 signifies --(CH.sub.2).sub.m R.sup.7 ; orR.sup.5 and R.sup.6 together with the N atom associated with them signify a heterocyclic residue;R.sup.7 signifies phenyl, substituted phenyl, cycloalkyl, heterocyclyl, lower-alkyl, cyano-lower-alkyl, hydroxy-lower-alkyl, di-lower-alkylamino-lower-alkyl, carboxy-lower-alkyl, lower-alkoxycarbonyl-lower-alkyl, lower-alkoxycarbonylamino-lower-alkyl or phenyl-lower-alkoxycarbonyl;R.sup.a signifies hydrogen, lower-alkyl or hydroxy;R.sup.b signifies hydrogen or lower-alkyl;Z signifies hydroxy, amino or a residue --OR.sup.8, --OC(O)NHR.sup.8, --OC(O)OR.sup.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: October 17, 2000
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
  • Patent number: 6004965
    Abstract: Compounds of the formula: ##STR1## where A, B, R.sup.1 -R.sup.8 are as described herein are endothelin inhibitors that can be used in treating diseases associated with endothelin, such as high blood pressure. Chemical synthesis of these compounds and pharmaceutical compositions containing these compounds are also useful.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: December 21, 1999
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
  • Patent number: 5962682
    Abstract: Compounds of formula (I) ##STR1## wherein R.sup.1 signifies phenyl, substituted phenyl or heterocyclyl; R.sup.2 signifies phenyl or substituted phenyl; R.sup.3 signifies hydrogen, lower-alkyl, cyano, carboxy, esterified carboxy, phenyl, substituted phenyl, heterocyclyl or a residue --CONR.sup.5 R.sup.6 or --NR.sup.5 COR.sup.7 ; R.sup.4 signifies hydrogen or lower-alkyl; R.sup.5 signifies hydrogen or a residue R.sup.7, and R.sup.6 signifies --(CH.sub.2).sub.m R.sup.7 ; or R.sup.5 and R.sup.6 together with the N atom associated with them signify a heterocyclic residue; R.sup.7 signifies phenyl, substituted phenyl, cycloalkyl, heterocyclyl, lower-alkyl, cyano-lower-alkyl, hydroxy-lower-alkyl, di-lower-alkylamino-lower-alkyl, carboxy-lower-alkyl, lower-alkoxycarbonyl-lower-alkyl, lower-alkoxycarbonylamino-lower-alkyl or phenyl-lower-alkoxycarbonyl; R.sup.a signifies hydrogen, lower-alkyl or hydroxy; R.sup.b signifies hydrogen or lower-alkyl; Z signifies hydroxy, amino or a residue --OR.sup.8, --OC(O)NHR.sup.
    Type: Grant
    Filed: August 18, 1997
    Date of Patent: October 5, 1999
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
  • Patent number: 5856484
    Abstract: Compounds of formula I: ##STR1## are disclosed. The compounds inhibit the binding of endothelin to its receptors.
    Type: Grant
    Filed: October 7, 1996
    Date of Patent: January 5, 1999
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
  • Patent number: 5837708
    Abstract: Compounds of the formula ##STR1## wherein the variables are hereinbelow defined. The compounds of formula I are inhibitors for endothelin receptors. They can be used for the treatment of disorders which are associated with endothelin activities, especially circulatory disorders such as hypertension, ischaemia, vasospasms and angina pectoris.
    Type: Grant
    Filed: October 15, 1996
    Date of Patent: November 17, 1998
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
  • Patent number: 5420129
    Abstract: The invention is concerned with novel sulphonamides and their use as medicaments. In particular, the invention is concerned with compounds of the formula ##STR1## wherein R.sup.1 is hydrogen, lower-alkyl, lower-alkoxy, lower-alkylthio, halogen or trifluoromethyl;R.sup.2 is hydrogen, lower-alkyl, halogen, lower-alkoxy, trifluoromethyl or --OCH.sub.2 COOR.sup.9 ;R.sup.3 is hydrogen, lower-alkyl, halogen, lower-alkylthio, trifluoromethyl, lower-alkoxy or trifluoromethoxy;R.sup.2 and R.sup.3 together are butadienyl, methylenedioxy, ethylenedioxy or isopropylidenedioxy;R.sup.
    Type: Grant
    Filed: December 8, 1993
    Date of Patent: May 30, 1995
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
  • Patent number: 5292740
    Abstract: The novel sulfonamides of formula I, ##STR1## in which the symbols R.sup.1 -R.sup.9, R.sup.a, R.sup.b, X, Y and n have the significance given in the description and salts thereof can be used for the treatment of circulatory disorders, especially hypertension, ischemia, vasopasms and angina pectoris.
    Type: Grant
    Filed: June 9, 1992
    Date of Patent: March 8, 1994
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Kaspar Burri, Martine Clozel, Walter Fischli, Georges Hirth, Bernd-Michael Loffler, Werner Neidhart, Henri Ramuz