Patents by Inventor Michael Löffler
Michael Löffler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11932061Abstract: An electronic wheel unit for arrangement on a vehicle wheel of a vehicle, having at least one sensor for detecting at least one wheel operational parameter, a control device, which is designed to generate wheel operational data on the basis of the at least one wheel operational parameter, a radio device for transmitting radio data signals containing the wheel operational data, a power supply device for supplying electrical power to the wheel unit which has an energy-harvesting device for converting mechanical energy captured on a rotation of the vehicle wheel into electrical energy and an electric battery, wherein the electronic wheel unit furthermore has a switchover device for switching over between the energy-harvesting device, and the electric battery for the electrical power supply to the wheel unit, and the switchover device has an actuable switch and an actuating device for actuating the switch, wherein the at least one wheel operational parameter comprises an acceleration parameter, and the actuatingType: GrantFiled: December 4, 2020Date of Patent: March 19, 2024Assignee: Continental Automotive Technologies GmbHInventor: Michael Löffler
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Publication number: 20230399672Abstract: The present invention in various aspects and embodiments provides engineered bacterial strains having a modified genome that provides advantages in maintenance and biosynthetic processes when cultured at large scale. The present invention further provides methods for large-scale fermentation using the bacterial strains. In various embodiments, the strain engineering yields a reduction in cellular responses to micro-environmental stimuli imposed in large scale bioreactors.Type: ApplicationFiled: November 2, 2021Publication date: December 14, 2023Inventors: Martin ZIEGLER, Ralf TAKORS, Joana SIEMEN, Michael LÖFFLER, Christine Nicole S. SANTOS, Ajikumar Parayil KUMARAN
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Publication number: 20230079930Abstract: An electronic wheel unit for arrangement on a vehicle wheel of a vehicle, having at least one sensor for detecting at least one wheel operational parameter, a control device, which is designed to generate wheel operational data on the basis of the at least one wheel operational parameter, a radio device for transmitting radio data signals containing the wheel operational data, a power supply device for supplying electrical power to the wheel unit which has an energy-harvesting device for converting mechanical energy captured on a rotation of the vehicle wheel into electrical energy and an electric battery, wherein the electronic wheel unit furthermore has a switchover device for switching over between the energy-harvesting device, and the electric battery for the electrical power supply to the wheel unit, and the switchover device has an actuable switch and an actuating device for actuating the switch, wherein the at least one wheel operational parameter comprises an acceleration parameter, and the actuatingType: ApplicationFiled: December 4, 2020Publication date: March 16, 2023Applicant: Continental Automotive Technologies GmbHInventor: Michael Löffler
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Publication number: 20230065157Abstract: The invention relates to a method for identifying electronic wheel units (12-1 to 12-6b) arranged on vehicle wheels (W1-W6b) of a vehicle (1), by means of which method those electronic wheel units (12-3a, 12-3b; 12-4a, 12-4b; 12-5a, 12-5b; 12-6a, 12-6b) which are arranged on vehicle wheels (W3a, W3b; W4a, W4b; W5a, W5b; W6a, W6b) connected to one another for conjoint rotation are identified, the method comprising the steps of: acquiring a respective cumulative number (Ni) of revolutions of each of the vehicle wheels (W1-W6b) using the electronic wheel units (12-1 to 12-6b); comparing with one another the cumulative numbers (Ni) of revolutions of the vehicle wheels (W1-W6b), identifying those electronic wheel units (12-3a, 12-3b; 12-4a, 12-4b; 12-5a, 12-5b, 12-6a, 12-6b) for which the cumulative numbers (Ni) of revolutions at least approximately coincide as being arranged connected to one another for conjoint rotation.Type: ApplicationFiled: February 9, 2021Publication date: March 2, 2023Applicant: Continental Automotive Technologies GmbHInventor: Michael Löffler
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Patent number: 11358419Abstract: A method for detecting wheel units mounted at wheels of a vehicle and for detecting wheel mounting positions belonging to each of the wheel units is disclosed. The method comprises the steps of: positioning a mobile communication device at a predetermined start position with respect to the vehicle, moving the mobile communication device from the start position along a path around the vehicle, receiving RF signals from the wheel units and measuring the RF signal strengths thereof by the mobile communication device when moving along the path around the vehicle, performing an analysis of variations of the measured RF signal strengths of the received RF signals depending on the position of the mobile communication device along the path, identifying the wheel units and identifying the wheel mounting positions based on a result of the analysis.Type: GrantFiled: June 18, 2019Date of Patent: June 14, 2022Assignee: Continental Automotive GmbHInventors: Matthias Kretschmann, Parthiv Dharamshi, Michael Löffler, Jean-Philippe Boisset
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Patent number: 11325433Abstract: A method for reconfiguring a device for monitoring a tire, incorporating a pressure sensor and a communication module. The device may receive and store configuration data intrinsic to the tire. Based on pressure measurements and the configuration data, the device generates and stores advanced data relating to use of the tire over time. Following reception of new configuration data, the method includes: detecting a tire change based on the previously stored configuration data and the newly received configuration data, if a tire change is detected: erasing the advanced data from the memory means of the device, if not, retaining the advanced data in the memory of the device.Type: GrantFiled: May 27, 2019Date of Patent: May 10, 2022Assignees: CONTINENTAL AUTOMOTIVE FRANCE, CONTINENTAL AUTOMOTIVE GMBHInventors: Davy Ribreau, Jean-Philippe Boisset, Michael Löffler
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Patent number: 11230146Abstract: A method for determining a tread depth of a tread of a tire during operation of a vehicle comprising the tire, a controller for a vehicle for determining a tread depth of a tread of a tire of the vehicle, and a system for a vehicle, comprising such a controller and at least one electronic wheel unit, wherein there is provision to determine the tread depth based on a determined instantaneous dynamic wheel radius of a wheel, comprising the tire, of the vehicle and a determined instantaneous dynamic inside radius of the tire are disclosed. To improve the accuracy of determination of the tread depth a correction variable predetermined for the type of tire is taken into consideration, which correction variable characterizes the relationship between a change in the tread depth, and a change resulting therefrom in the difference between the dynamic wheel radius and the dynamic inside radius.Type: GrantFiled: March 20, 2018Date of Patent: January 25, 2022Inventors: Alexander Kuerzl, Matthias Kretschmann, Michael Löffler
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Publication number: 20210268849Abstract: A method for detecting wheel units mounted at wheels of a vehicle and for detecting wheel mounting positions belonging to each of the wheel units is disclosed. The method comprises the steps of: positioning a mobile communication device at a predetermined start position with respect to the vehicle moving the mobile communication device from the start position along a path around the vehicle receiving RF signals from the wheel units and measuring the RF signal strengths thereof by the mobile communication device when moving along the path around the vehicle performing an analysis of variations of the measured RF signal strengths of the received RF signals depending on the position of the mobile communication device along the path identifying the wheel units and identifying the wheel mounting positions based on a result of the analysis.Type: ApplicationFiled: June 18, 2019Publication date: September 2, 2021Inventors: Matthias Kretschmann, Parthiv Dharamshi, Michael Löffler, Jean-Philippe Boisset
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Publication number: 20210268851Abstract: Disclosed are a method and a system for detecting a faulty arrangement of a sensor module in a sensor module holder in a tire of a vehicle equipped with a tire monitoring system. The detection of a faulty arrangement of a sensor module may be performed by ascertaining on the basis of a comparison of the operating parameters determined by the sensor modules of the tire monitoring system that there is for this sensor module a discrepancy, dependent on a speed of the vehicle, between the operating parameter and an operating parameter to be expected for this sensor module.Type: ApplicationFiled: July 3, 2019Publication date: September 2, 2021Inventors: Parthiv Dharamshi, Matthias Kretschmann, Shichao You, Michael Löffler
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Publication number: 20210206211Abstract: A method for reconfiguring a device for monitoring a tire, incorporating a pressure sensor and a communication module. The device may receive and store configuration data intrinsic to the tire. Based on pressure measurements and the configuration data, the device generates and stores advanced data relating to use of the tire over time. Following reception of new configuration data, the method includes: detecting a tire change based on the previously stored configuration data and the newly received configuration data, if a tire change is detected: erasing the advanced data from the memory means of the device, if not, retaining the advanced data in the memory of the device.Type: ApplicationFiled: May 27, 2019Publication date: July 8, 2021Inventors: Davy Ribreau, Jean-Philippe Boisset, Michael Löffler
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Publication number: 20200070589Abstract: A method for determining a tread depth of a tread of a tire during operation of a vehicle comprising the tire, a controller for a vehicle for determining a tread depth of a tread of a tire of the vehicle, and a system for a vehicle, comprising such a controller and at least one electronic wheel unit, wherein there is provision to determine the tread depth based on a determined instantaneous dynamic wheel radius of a wheel, comprising the tire, of the vehicle and a determined instantaneous dynamic inside radius of the tire are disclosed. To improve the accuracy of determination of the tread depth a correction variable predetermined for the type of tire is taken into consideration, which correction variable characterizes the relationship between a change in the tread depth, and a change resulting therefrom in the difference between the dynamic wheel radius and the dynamic inside radius.Type: ApplicationFiled: March 20, 2018Publication date: March 5, 2020Inventors: Alexander Kuerzl, Matthias Kretschmann, Michael Löffler
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Publication number: 20100162994Abstract: The present invention relates to a valve device (13) for controlling a gas flow in a fresh air system (6) of an internal combustion engine (2), in particular of a motor vehicle, with a housing (17) which encloses at least one duct section (19) through which the gas flow (14) can pass transversely to the main flow direction (18), with at least one flap (15) which can be rotated about an axis of rotation (21) which runs transversely with respect to the main flow direction (18) in the duct section (19). In order to improve the fail-safety of the valve device (13), at least one rotary frame (24) is provided, which can be rotated about an axis of rotation (25) which runs transversely with respect to the main flow direction (18) in the duct section (19) and has a frame opening (26) through which the gas flow (14) can pass.Type: ApplicationFiled: December 17, 2009Publication date: July 1, 2010Inventors: Alfred Elsäßer, Patric Genieser, Dietmar Türpe, Michael Löffler
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Publication number: 20060048538Abstract: A sorptive heat exchanger (E), which presents a plurality of heat exchange channels (10) in thermal contact with respective sorption channels (11), where sorption material (12) is fixed on the internal surfaces of channels (11).Type: ApplicationFiled: May 9, 2003Publication date: March 9, 2006Inventors: Michael Loffler, Hans Henning
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Aryl- and hetaryl-sulfonamide derivatives, their preparation and their use as endothelin antagonists
Patent number: 6133442Abstract: Compounds of formula I ##STR1## wherein R.sup.1 signifies phenyl, substituted phenyl or heterocyclyl;R.sup.2 signifies phenyl or substituted phenyl;R.sup.3 signifies hydrogen, lower-alkyl, cyano, carboxy, esterified carboxy, phenyl, substituted phenyl, heterocyclyl or a residue --CONR.sup.5 R.sup.6 or --NR.sup.5 COR.sup.7 ;R.sup.4 signifies hydrogen or lower-alkyl;R.sup.5 signifies hydrogen or a residue R.sup.7, andR.sup.6 signifies --(CH.sub.2).sub.m R.sup.7 ; orR.sup.5 and R.sup.6 together with the N atom associated with them signify a heterocyclic residue;R.sup.7 signifies phenyl, substituted phenyl, cycloalkyl, heterocyclyl, lower-alkyl, cyano-lower-alkyl, hydroxy-lower-alkyl, di-lower-alkylamino-lower-alkyl, carboxy-lower-alkyl, lower-alkoxycarbonyl-lower-alkyl, lower-alkoxycarbonylamino-lower-alkyl or phenyl-lower-alkoxycarbonyl;R.sup.a signifies hydrogen, lower-alkyl or hydroxy;R.sup.b signifies hydrogen or lower-alkyl;Z signifies hydroxy, amino or a residue --OR.sup.8, --OC(O)NHR.sup.8, --OC(O)OR.sup.Type: GrantFiled: March 5, 1999Date of Patent: October 17, 2000Assignee: Hoffmann-La Roche Inc.Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz -
Patent number: 6004965Abstract: Compounds of the formula: ##STR1## where A, B, R.sup.1 -R.sup.8 are as described herein are endothelin inhibitors that can be used in treating diseases associated with endothelin, such as high blood pressure. Chemical synthesis of these compounds and pharmaceutical compositions containing these compounds are also useful.Type: GrantFiled: August 15, 1997Date of Patent: December 21, 1999Assignee: Hoffmann-La Roche Inc.Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
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Aryl- and hetaryl-sulfonamide derivatives, their preparation and their use as endothelin antagonists
Patent number: 5962682Abstract: Compounds of formula (I) ##STR1## wherein R.sup.1 signifies phenyl, substituted phenyl or heterocyclyl; R.sup.2 signifies phenyl or substituted phenyl; R.sup.3 signifies hydrogen, lower-alkyl, cyano, carboxy, esterified carboxy, phenyl, substituted phenyl, heterocyclyl or a residue --CONR.sup.5 R.sup.6 or --NR.sup.5 COR.sup.7 ; R.sup.4 signifies hydrogen or lower-alkyl; R.sup.5 signifies hydrogen or a residue R.sup.7, and R.sup.6 signifies --(CH.sub.2).sub.m R.sup.7 ; or R.sup.5 and R.sup.6 together with the N atom associated with them signify a heterocyclic residue; R.sup.7 signifies phenyl, substituted phenyl, cycloalkyl, heterocyclyl, lower-alkyl, cyano-lower-alkyl, hydroxy-lower-alkyl, di-lower-alkylamino-lower-alkyl, carboxy-lower-alkyl, lower-alkoxycarbonyl-lower-alkyl, lower-alkoxycarbonylamino-lower-alkyl or phenyl-lower-alkoxycarbonyl; R.sup.a signifies hydrogen, lower-alkyl or hydroxy; R.sup.b signifies hydrogen or lower-alkyl; Z signifies hydroxy, amino or a residue --OR.sup.8, --OC(O)NHR.sup.Type: GrantFiled: August 18, 1997Date of Patent: October 5, 1999Assignee: Hoffmann-La Roche Inc.Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz -
Patent number: 5856484Abstract: Compounds of formula I: ##STR1## are disclosed. The compounds inhibit the binding of endothelin to its receptors.Type: GrantFiled: October 7, 1996Date of Patent: January 5, 1999Assignee: Hoffmann-La Roche Inc.Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
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Patent number: 5837708Abstract: Compounds of the formula ##STR1## wherein the variables are hereinbelow defined. The compounds of formula I are inhibitors for endothelin receptors. They can be used for the treatment of disorders which are associated with endothelin activities, especially circulatory disorders such as hypertension, ischaemia, vasospasms and angina pectoris.Type: GrantFiled: October 15, 1996Date of Patent: November 17, 1998Assignee: Hoffmann-La Roche Inc.Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
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Patent number: 5420129Abstract: The invention is concerned with novel sulphonamides and their use as medicaments. In particular, the invention is concerned with compounds of the formula ##STR1## wherein R.sup.1 is hydrogen, lower-alkyl, lower-alkoxy, lower-alkylthio, halogen or trifluoromethyl;R.sup.2 is hydrogen, lower-alkyl, halogen, lower-alkoxy, trifluoromethyl or --OCH.sub.2 COOR.sup.9 ;R.sup.3 is hydrogen, lower-alkyl, halogen, lower-alkylthio, trifluoromethyl, lower-alkoxy or trifluoromethoxy;R.sup.2 and R.sup.3 together are butadienyl, methylenedioxy, ethylenedioxy or isopropylidenedioxy;R.sup.Type: GrantFiled: December 8, 1993Date of Patent: May 30, 1995Assignee: Hoffmann-La Roche Inc.Inventors: Volker Breu, Kaspar Burri, Jean-Marie Cassal, Martine Clozel, Georges Hirth, Bernd-Michael Loffler, Marcel Muller, Werner Neidhart, Henri Ramuz
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Patent number: 5292740Abstract: The novel sulfonamides of formula I, ##STR1## in which the symbols R.sup.1 -R.sup.9, R.sup.a, R.sup.b, X, Y and n have the significance given in the description and salts thereof can be used for the treatment of circulatory disorders, especially hypertension, ischemia, vasopasms and angina pectoris.Type: GrantFiled: June 9, 1992Date of Patent: March 8, 1994Assignee: Hoffmann-La Roche Inc.Inventors: Kaspar Burri, Martine Clozel, Walter Fischli, Georges Hirth, Bernd-Michael Loffler, Werner Neidhart, Henri Ramuz