Abstract: An IOP control device for implantation in an eye of a patient is disclosed. The device includes a housing and a multilayer membrane. The housing is sized for implantation into the eye and includes an entrance port and an exit port. The membrane is anchored within the housing to form a flow control chamber on a first side and a fluid flow passageway on a second opposing side of the membrane. The chamber is arranged to contain a gas creating a chamber pressure, and the membrane is configured to affect flow through the passageway from the entrance port to the exit port by deflecting in response to changes in the chamber pressure. The membrane comprises a first layer having a higher permeability and a higher flexibility than the second layer, which is disposed adjacent the first layer and restricts the diffusion of gas in the chamber through the membrane.

Abstract: A membrane actuator device includes a housing with an entrance port and an exit port connected by a fluid flow passageway. A gas generation chamber is disposed within the housing, the gas generation chamber comprising a first opening and a gas generating element. A membrane actuation chamber has a second opening and may be defined at least in part by a flexible membrane configured to deflect and affect fluid flow through the fluid flow passageway. A barrier spans the width of the first opening of the gas generation chamber and is disposed in a manner that reduces the likelihood that gas molecules will pass from the gas generation chamber to the membrane actuation chamber.

Abstract: A membrane actuator device includes a housing with an entrance port and an exit port connected by a fluid flow passageway. A gas generation chamber is disposed within the housing, the gas generation chamber comprising a first opening and a gas generating element. A membrane actuation chamber has a second opening and may be defined at least in part by a flexible membrane configured to deflect and affect fluid flow through the fluid flow passageway. A barrier spans the width of the first opening of the gas generation chamber and is disposed in a manner that reduces the likelihood that gas molecules will pass from the gas generation chamber to the membrane actuation chamber.

Abstract: A drainage device for implantation in an eye of a patient to treat an ocular condition includes a first tube configured to extend into an anterior chamber of the eye and convey aqueous humor from the anterior chamber. An exit portion is in fluid communication with the distal end portion. A passage extends between the distal portion of the first tube and the exit portion, with a liquid disposed in the passage. The implant may include a first seal associated with the distal end portion and a second seal associated with the exit portion to prevent drainage of the liquid through the exit portion. The implant may include an implant body disposed between the distal end portion and the exit portion, the passage extending through the implant body. The implant body may comprise a fluid-sensitive component in fluid communication with the passage that may be formed of a flexible membrane.

Abstract: An IOP control device for implantation in an eye of a patient is disclosed. The device includes a housing and a multilayer membrane. The housing is sized for implantation into the eye and includes an entrance port and an exit port. The membrane is anchored within the housing to form a flow control chamber on a first side and a fluid flow passageway on a second opposing side of the membrane. The chamber is arranged to contain a gas creating a chamber pressure, and the membrane is configured to affect flow through the passageway from the entrance port to the exit port by deflecting in response to changes in the chamber pressure. The membrane comprises a first layer having a higher permeability and a higher flexibility than the second layer, which is disposed adjacent the first layer and restricts the diffusion of gas in the chamber through the membrane.