Abstract: A method of analysing the magnitude of Magnetic Resonance Imaging (MRI) data is described. The method comprising: using the magnitude only of the multi-echo MRI data of images from the subject, where images are acquired at arbitrarily timed echoes including at least one echo time where water and fat are not substantially in-phase; fitting the magnitude of said multi-echo MRI data to a single signal model to produce a plurality of potential solutions for the relative signal contributions for each of the at least two species from the model, by using a plurality of different starting conditions to generate a particular cost function value for each of the plurality of starting conditions, where said cost function values are independent of a field map term for the MRI data; analysing said cost function values to calculate relative signal separation contribution for each species at each voxel of the images.

Abstract: A method of analysing the magnitude of Magnetic Resonance Imaging (MRI) data is described. The method comprising: using the magnitude only of the multi-echo MRI data of images from the subject, where images are acquired at arbitrarily timed echoes including at least one echo time where water and fat are not substantially in-phase; fitting the magnitude of said multi-echo MRI data to a single signal model to produce a plurality of potential solutions for the relative signal contributions for each of the at least two species from the model, by using a plurality of different starting conditions to generate a particular cost function value for each of the plurality of starting conditions, where said cost function values are independent of a field map term for the MRI data; analysing said cost function values to calculate relative signal separation contribution for each species at each voxel of the images.

Abstract: A multi-pulse radio frequency signal sequence includes a 90.degree. excitation pulse (50) and at least a first 180.degree. refocusing pulse (52) and a second 180.degree. refocusing pulse (54). The excitation pulse and first refocusing pulse are separated by a duration A and the first and second refocusing pulses are separated by A+B. A free induction decay (60) follows the excitation pulse, a first spin echo (62) occurs a duration A after the first refocusing pulse and a second spin echo (64) occurs the duration B after the second refocusing pulse. A first read gradient (90) is applied between the excitation and first refocusing pulses; a second read gradient (92) is applied between the first refocusing pulse and the first spin echo; a third read gradient (94) is applied between the first spin echo and the second refocusing pulse; and a fourth read gradient (96) is applied between the second refocusing pulse and the second spin echo. Because the 90.degree. and 180.degree.

Abstract: In a steady state free precession (SFP) magnetic resonance imaging method, after each pulse of an applied train of phase coherent RF pulses which excite magnetic resonance spins in a region of a body being examined, magnetic field gradients are applied to encode the excited spins and the encoded spins are detected, and at least one further magnetic field gradient is then applied to rephase the spins by the time the next RF pulse is applied.