Patents by Inventor Michael L. Merchant

Michael L. Merchant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10041956
    Abstract: Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: August 7, 2018
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Michael L. Merchant, Jon B. Klein, Michael E. Brier, Adam E. Gaweda
  • Patent number: 9588128
    Abstract: The presently-disclosed subject matter provides methods for diagnosing a cardiovascular disease in a subject by determining an amount of one or more peptide biomarkers disclosed herein in a biological sample from the subject. The presently-disclosed subject matter further provides methods for determining treatment efficacy and/or progression of a cardiovascular disease in a subject by measuring amounts of one or more of the biomarkers in a biological sample from the subject. The presently-disclosed subject matter also provides antibodies and kits for measuring the biomarkers.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: March 7, 2017
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Jon Klein, Michael L. Merchant, Rosemary Ouseph, Richard A. Ward
  • Publication number: 20150247868
    Abstract: Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent.
    Type: Application
    Filed: May 14, 2015
    Publication date: September 3, 2015
    Inventors: Michael L. Merchant, Jon B. Klein, Michael E. Brier, Adam E. Gaweda
  • Patent number: 9057731
    Abstract: Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. Kits for predicting a response to an erythropoietic agent are further provided and include one or more antibodies, or fragments thereof, that specifically recognize a peptide of SEQ ID NOS: 1-17.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: June 16, 2015
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Michael L. Merchant, Jon B. Klein, Michael E. Brier, Adam E. Gaweda
  • Publication number: 20140243432
    Abstract: The presently-disclosed subject matter provides methods for diagnosing a cardiovascular disease in a subject by determining an amount of one or more peptide biomarkers disclosed herein in a biological sample from the subject. The presently-disclosed subject matter further provides methods for determining treatment efficacy and/or progression of a cardiovascular disease in a subject by measuring amounts of one or more of the biomarkers in a biological sample from the subject. The presently-disclosed subject matter also provides antibodies and kits for measuring the biomarkers.
    Type: Application
    Filed: April 11, 2014
    Publication date: August 28, 2014
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Jon Klein, Michael L. Merchant, Rosemary Ouseph, Richard A. Ward
  • Patent number: 8703435
    Abstract: The presently-disclosed subject matter provides methods for diagnosing a cardiovascular disease in a subject by determining an amount of one or more peptide biomarkers disclosed herein in a biological sample from the subject. The presently-disclosed subject matter further provides methods for determining treatment efficacy and/or progression of a cardiovascular disease in a subject by measuring amounts of one or more of the biomarkers in a biological sample from the subject. The presently-disclosed subject matter also provides antibodies and kits for measuring the biomarkers.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: April 22, 2014
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Jon Klein, Michael L. Merchant, Rosemary Ouseph, Richard A. Ward
  • Publication number: 20110318761
    Abstract: Methods for predicting a response to an erythropoietic agent in a subject include providing a biological sample from the subject, and determining an amount in the sample of at least one peptide selected from the group consisting of SEQ ID NOS: 1-17. If there is a measurable difference in the amount of the at least one peptide in the sample, when compared to a control level of the same peptide, the subject is then predicted to have a good response or a poor response to the erythropoietic agent. Kits for predicting a response to an erythropoietic agent are further provided and include one or more antibodies, or fragments thereof, that specifically recognize a peptide of SEQ ID NOS: 1-17.
    Type: Application
    Filed: June 23, 2011
    Publication date: December 29, 2011
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Michael L. Merchant, Jon B. Klein, Michael E. Brier, Adam E. Gaweda
  • Publication number: 20100124552
    Abstract: The presently-disclosed subject matter provides methods for diagnosing a cardiovascular disease in a subject by determining an amount of one or more peptide biomarkers disclosed herein in a biological sample from the subject. The presently-disclosed subject matter further provides methods for determining treatment efficacy and/or progression of a cardiovascular disease in a subject by measuring amounts of one or more of the biomarkers in a biological sample from the subject. The presently-disclosed subject matter also provides antibodies and kits for measuring the biomarkers.
    Type: Application
    Filed: April 18, 2008
    Publication date: May 20, 2010
    Applicant: University of Louisville Research Foundation, Inc.
    Inventors: Jon Klein, Michael L. Merchant, Rosemary Ouseph, Richard A. Ward