Patents by Inventor Michael L. Norton

Michael L. Norton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8986982
    Abstract: A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: March 24, 2015
    Assignee: Marshall University Research Corporation
    Inventors: Derek A. Gregg, Elizabeth E. Murray, Michael L. Norton, Justin T. Swick, Herbert Tesser
  • Patent number: 8293471
    Abstract: A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: October 23, 2012
    Assignee: Marshall University Research Corporation
    Inventors: Derek A. Gregg, Elizabeth E. Murray, Michael L. Norton, Justin T. Swick, Herbert Tesser
  • Publication number: 20090325234
    Abstract: A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
    Type: Application
    Filed: January 28, 2005
    Publication date: December 31, 2009
    Inventors: Derek A. Gregg, Elizabeth E. Murray, Michael L. Norton, Justin T. Swick, Herbert Tesser
  • Publication number: 20040005613
    Abstract: The present invention concerns the detection of single nucleotide polymorphisms in a sample. The present invention discloses methods for detecting single nucleotide polymorphisms in a sample. The present invention further discloses nucleic acid probes and accessory molecules useful in the methods of the invention.
    Type: Application
    Filed: May 20, 2003
    Publication date: January 8, 2004
    Inventor: Michael L. Norton
  • Patent number: 5256260
    Abstract: The electrodeposition of bismuth based materials and superconductors is achieved under isothermal, constant potential conditions using a three electrode, one compartment cell geometry operating at temperature below about 450.degree. C.
    Type: Grant
    Filed: August 16, 1991
    Date of Patent: October 26, 1993
    Assignee: University of Georgia Research Foundation
    Inventors: Michael L. Norton, Horng-Yi Tang