Patents by Inventor Michael L. Opel

Michael L. Opel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230392185
    Abstract: Methods for identifying and providing information about inhibiting growth of polymicrobial infections, including but not limited to providing statistics or information about the likelihood of success in inhibiting growth of a polymicrobial infection with particular compositions or therapeutic solutions. The methods herein feature detection and identification of organisms of the polymicrobial sample (e.g., polymicrobial infection), phenotypic pooled sensitivity tests for determining the susceptibility or resistance of the polymicrobial sample (e.g., polymicrobial infection) in the sample to an antibiotic or other therapeutic agent, and identification of resistance genes, e.g., genetic markers that may indicate resistance to a particular treatment. Together, the data can be applied against databases of antibiotic/therapeutic susceptibility or resistance for particular known polymicrobial samples (e.g.
    Type: Application
    Filed: August 17, 2023
    Publication date: December 7, 2023
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Publication number: 20230357818
    Abstract: Methods for detecting and treating polymicrobial infections, wherein a mixed population of microbes (e.g., bacteria) are present in a patient sample and the microbes are not first isolated from the sample. For example, the present invention describes specific polymicrobial infections and methods of treating said infections, wherein a particular antibiotic or a group of antibiotics are selected based on the composition of the polymicrobial infections.
    Type: Application
    Filed: July 12, 2023
    Publication date: November 9, 2023
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Publication number: 20230357817
    Abstract: Methods for detecting and treating polymicrobial infections, wherein a mixed population of microbes (e.g., bacteria) are present in a patient sample and the microbes are not first isolated from the sample. For example, the present invention describes specific polymicrobial infections and methods of treating said infections, wherein a particular antibiotic or a group of antibiotics are selected based on the composition of the polymicrobial infections.
    Type: Application
    Filed: July 12, 2023
    Publication date: November 9, 2023
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Patent number: 11746371
    Abstract: Methods for detecting and treating polymicrobial infections, wherein a mixed population of microbes (e.g., bacteria) are present in a patient sample and the microbes are not first isolated from the sample. For example, the present invention describes specific polymicrobial infections and methods of treating said infections, wherein a particular antibiotic or a group of antibiotics are selected based on the composition of the polymicrobial infections.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: September 5, 2023
    Assignee: CAP DIAGNOSTICS, LLC
    Inventors: David A. Baunoch, Miguel F. R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Publication number: 20220315975
    Abstract: Methods for identifying and providing therapeutic solutions for treating polymicrobial infections, such as but not limited to urinary tract infections, based on concordance between ABR genes and antibiotic susceptibility. The methods herein feature detection and identification of organisms of the polymicrobial infection, phenotypic pooled sensitivity tests for determining the susceptibility or resistance of the polymicrobial infection in the sample to an antibiotic or other therapeutic agent, and identification of resistance genes, e.g., genetic markers that may indicate resistance to a particular treatment. Together, the data can be applied against databases of antibiotic/therapeutic susceptibility or resistance for particular known polymicrobial infections in order to provide one or more therapeutic solutions for the polymicrobial infection.
    Type: Application
    Filed: June 1, 2022
    Publication date: October 6, 2022
    Inventors: David A. Baunoch, Natalie Luke, Michael L. Opel
  • Publication number: 20210301315
    Abstract: Methods for detecting and treating polymicrobial infections, wherein a mixed population of microbes (e.g., bacteria) are present in a patient sample and the microbes are not first isolated from the sample. For example, the present invention describes specific polymicrobial infections and methods of treating said infections, wherein a particular antibiotic or a group of antibiotics are selected based on the composition of the polymicrobial infections.
    Type: Application
    Filed: June 1, 2021
    Publication date: September 30, 2021
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Patent number: 11053532
    Abstract: Methods for detecting and treating polymicrobial infections, wherein a mixed population of microbes (e.g., bacteria) are present in a patient sample and the microbes are not first isolated from the sample. For example, the present invention describes specific polymicrobial infections and methods of treating said infections, wherein a particular antibiotic or a group of antibiotics are selected based on the composition of the polymicrobial infections.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: July 6, 2021
    Assignee: CAP DIAGNOSTICS, LLC
    Inventors: David A. Baunoch, Miguel F. R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Publication number: 20210172000
    Abstract: Methods for identifying and providing therapeutic solutions for treating polymicrobial infections, such as but not limited to urinary tract infections. The methods herein feature detection and identification of organisms of the polymicrobial infection, phenotypic pooled sensitivity tests for determining the susceptibility or resistance of the polymicrobial infection in the sample to an antibiotic or other therapeutic agent, and identification of resistance genes, e.g., genetic markers that may indicate resistance to a particular treatment. Together, the data can be applied against databases of antibiotic/therapeutic susceptibility or resistance for particular known polymicrobial infections in order to provide one or more therapeutic solutions for the polymicrobial infection.
    Type: Application
    Filed: February 17, 2021
    Publication date: June 10, 2021
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Publication number: 20200347433
    Abstract: Methods for detecting and treating polymicrobial infections, wherein a mixed population of microbes (e.g., bacteria) are present in a patient sample and the microbes are not first isolated from the sample. For example, the present invention describes specific polymicrobial infections and methods of treating said infections, wherein a particular antibiotic or a group of antibiotics are selected based on the composition of the polymicrobial infections.
    Type: Application
    Filed: April 14, 2020
    Publication date: November 5, 2020
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir, Natalie Luke
  • Publication number: 20190153501
    Abstract: Disclosed herein are methods determining susceptibility of bacteria in a sample from a subject suspected of having an infection to a plurality of antibiotics simultaneously, wherein the sample is tested without first isolating the bacteria from the sample.
    Type: Application
    Filed: December 11, 2018
    Publication date: May 23, 2019
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir
  • Patent number: 10160991
    Abstract: Disclosed herein are methods determining susceptibility of bacteria in a sample from a subject suspected of having an infection to a plurality of antibiotics simultaneously, wherein the sample is tested without first isolating the bacteria from the sample.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: December 25, 2018
    Assignee: CAP DIAGNOSTICS, LLC
    Inventors: David A. Baunoch, Miguel F. R. Penaranda, Michael L. Opel, Maher Badir
  • Publication number: 20180305730
    Abstract: Disclosed herein are methods determining susceptibility of bacteria in a sample from a subject suspected of having an infection to a plurality of antibiotics simultaneously, wherein the sample is tested without first isolating the bacteria from the sample.
    Type: Application
    Filed: April 19, 2018
    Publication date: October 25, 2018
    Inventors: David A. Baunoch, Miguel F.R. Penaranda, Michael L. Opel, Maher Badir