Patents by Inventor Michael L. Siegel

Michael L. Siegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of cancer using GFR alpha-4 chimeric antigen receptor
    Patent number: 11970525
    Abstract: The present invention relates to compositions and methods for treating diseases, disorders or conditions associated with the expression of the Glycosyl-phosphatidylinositol (GPI)-linked GDNF family ?-receptor 4 (GFR?4).
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: April 30, 2024
    Assignees: The Trustees of the University of Pennsylvania, Novartis AG, The Scripps Research Institute
    Inventors: Donald L. Siegel, Michael C. Milone, Vijay Bhoj, Christoph Rader
  • 1?-cyano nucleoside analogs and uses thereof
    Patent number: 11939347
    Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: March 26, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Daniel H. Byun, Byoung-Kwon Chun, Michael O. Clarke, Petr Jansa, Rao V. Kalla, Dmitry Koltun, Richard L. Mackman, Thao D. Perry, Dustin S. Siegel, Scott P. Simonovich
  • CD73 compounds
    Patent number: 11919869
    Abstract: Provided herein is A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.
    Type: Grant
    Filed: October 27, 2022
    Date of Patent: March 5, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Mark J. Bartlett, Gregory F. Chin, Michael O. Clarke, Jennifer L Cosman, Deeba Ensan, Bindu Goyal, Stephen Ho, Richard L Mackman, Michael R. Mish, Dustin S. Siegel, Kyle C. Tamshen, Hai Yang
  • Sport novelty missile
    Patent number: 7727097
    Abstract: A sport novelty ball has an outer shell and a stabilizing shock absorbing core in which various interior components are embedded. A non-toxic smoke solution is introduced into the ball and stored. Centrally located within the ball is a smoke chamber containing a heating element, A switch/pump assembly is provided for completing an electrical circuit and moving the smoke solution through the ball. Upon actuation of the switch/pump assembly, simultaneously the heating element is actuated and the solution is pressured through fluid lines in the ball to an atomizer for spraying the solution onto the heating element, whereupon smoke is generated in the smoke chamber. Exhaust/intake channels extend from the smoke chamber to the ball periphery. When the ball is thrown, ambient air passing through the exhaust/intake channels causes a stream of air to be emitted from the channels, giving the appearance that the ball is smoking.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: June 1, 2010
    Inventors: Michael L. Siegel, Paul Schefflein, Michael G. D'Agostino
  • Sport novelty missile
    Publication number: 20090042677
    Abstract: A sport novelty ball has an outer shell and a stabilizing shock absorbing core in which various interior components are embedded. A non-toxic smoke solution is introduced into the ball and stored. Centrally located within the ball is a smoke chamber containing a heating element, A switch/pump assembly is provided for completing an electrical circuit and moving the smoke solution through the ball. Upon actuation of the switch/pump assembly, simultaneously the heating element is actuated and the solution is pressured through fluid lines in the ball to an atomizer for spraying the solution onto the heating element, whereupon smoke is generated in the smoke chamber. Exhaust/intake channels extend from the smoke chamber to the ball periphery. When the ball is thrown, ambient air passing through the exhaust/intake channels causes a stream of air to be emitted from the channels, giving the appearance that the ball is smoking.
    Type: Application
    Filed: August 8, 2007
    Publication date: February 12, 2009
    Inventors: Michael L. Siegel, Paul Schefflein, Michael G. D'Agostino