Abstract: A hybrid passenger vehicle includes a chassis supported by at least one front wheel and at least one rear wheel, a body coupled to the chassis including at least one door, and a vehicle floor coupled to the chassis. The body defines an interior space configured to be occupied by at least one passenger when operating the vehicle, and the vehicle floor has a front end and a rear end. A rear wall is coupled to the rear end of the vehicle floor such that the rear wall defines a rearmost boundary of the vehicle floor. A rear suspension assembly is coupled to the chassis. The rear wall is arc-shaped, and the rear suspension assembly is located rearward of the rear wall.

Abstract: This invention describes compositions comprising at least 75 mg/mL of solubilized otherwise poorly soluble drug in an aqueous environment, wherein the composition further comprises a combination of 3 or more acids. Methods of providing analgesia, anti-pyretic effects or reducing pain in a subject presenting with a pain condition, and methods of reducing administration site irritation, inflammation or a combination thereof in a subject presenting with a pain condition, comprising the steps of administering such compositions and infusion pumps containing such compositions are also described.

Abstract: Exhaust assemblies for vehicles and methods of installing exhaust systems on vehicles are disclosed. An exhaust assembly for a vehicle includes an exhaust inlet to receive combustion products from a drive unit, a catalytic converter to control emissions from combustion products received by the exhaust system, and a first piping assembly coupled to the exhaust inlet and the catalytic converter.

Abstract: A baseball or softball alignment training device comprising a first leg having a general length and having a first end at one end of the general length and a second end at the distal end opposite from said first end. A second leg having a general length and having a first end at one end of the general length and a second end at the distal and opposite from said first end. Aa first hinge member carried by the second end of said first leg. The first hinge member having a first abutment edge. The second hinge member carried by the second end of the second leg. The second hinge member having a second abutment edge. The first and second hinge members pivotally interconnected and wherein the first abutment edge of the first hinge member abuts the second abutment edge of the second hinge member at a position wherein the first leg and the second leg are perpendicular to each other forming a right angle.

Abstract: Pharmaceutical compositions comprising imatinib or a derivative thereof for treatment of a pulmonary disease via inhalation. Methods of treating a pulmonary disease include administering by inhalation an effective amount of imatinib or a derivative thereof to a patient in need thereof. In aspects, the pharmaceutical composition provided herein comprises an aqueous solution or suspension of imatinib or a derivative thereof that is formulated for inhalatory administration.

Abstract: Pharmaceutical compositions comprising an antiarrhythmic agent for treatment of a heart condition via inhalation. Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also disclosed.

Abstract: A removable seat assembly for a vehicle, including a base assembly having a riser portion configured to support a seat; a frame structure coupled to and supporting the riser portion, the frame structure defining a first generally planar surface configured to support a floor section; a seat dolly coupled to the frame structure, the seat dolly including a plurality of wheels for moving the seat assembly from a first position to a second position; a floor base assembly defining a substantially planar surface for receiving the plurality of wheels of the seat dolly as the seat assembly is moved from the first position to the second position; and a mounting bracket configured to releasably lock the seat dolly to the floor base assembly.

Abstract: The present disclosure relates to eukaryotic cell lines with a stable integrated loss-of-function or attenuation-of-function mutation in each of the Bax and Bak genes. Also provided are methods of producing such cell lines. This disclosure also relates to compositions and cell cultures comprising such cell lines, as well as methods of producing a product, such as a recombinant polypeptide or viral vector, using said cells, compositions and cell cultures.

Abstract: A hybrid passenger vehicle includes a chassis supported by at least one front wheel and at least one rear wheel, a body coupled to the chassis including at least one door, and a vehicle floor coupled to the chassis. The body defines an interior space configured to be occupied by at least one passenger when operating the vehicle, and the vehicle floor has a front end and a rear end. A rear wall is coupled to the rear end of the vehicle floor such that the rear wall defines a rearmost boundary of the vehicle floor. A rear suspension assembly is coupled to the chassis. The rear wall is arc-shaped, and the rear suspension assembly is located rearward of the rear wall.

Abstract: A payment object service receives a request from a giver to associate a payment amount to an object. The request includes one or more images of the object and recipient information, which the payment object service uses to determine whether the association between these images and the information is unique. If the association is unique, the payment object service updates a database to associate the payment amount to the object and enable redemption of the payment amount. When the payment object service receives a request to redeem at least a portion of the payment amount, the payment object service may use one or more images and recipient information obtained from the request to verify that the images and information together correspond to the object. Once the redemption is complete, the payment object service may update the database to specify the current remaining payment amount.

Abstract: Pharmaceutical compositions comprising an antiarrhythmic agent for treatment of a heart condition via inhalation. Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also disclosed.

Abstract: Pharmaceutical compositions comprising an antiarrhythmic agent for treatment of a heart condition via inhalation. Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also disclosed.

Abstract: Pharmaceutical compositions comprising an antiarrhythmic agent for treatment of a heart condition via inhalation. Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also disclosed.

Abstract: Pharmaceutical compositions comprising an antiarrhythmic agent for treatment of a heart condition via inhalation. Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also disclosed.

Abstract: A ramp assembly for use to accommodate a wheel-chaired passenger to enter or exit a motorized vehicle includes a ramp body having a length defined along a longitudinal direction, a first side rail pivotably coupled to the ramp body, a second side rail pivotably coupled to the ramp body, and a hinge plate pivotably coupled to the ramp body. The ramp assembly further includes a first arm and a second arm coupled to a bottom surface of the ramp body. The first side rail and second side rail are pivotably moved between a folded position in which the first and second side rails pivot inwardly and a raised position in which the side rails are oriented perpendicular to the ramp body. The first arm operably pivots the first side rail between its folded and raised position, and the second arm operably pivots the second side rail between its folded and raised position.

Abstract: The invention provides a fluid working machine comprising: a crankshaft (2) which is rotatable about an axis of rotation (3); adjacent first and second groups (5, 6, 8, 10) of valve cylinder devices (13) spaced from each other about the axis of rotation (3), one or each of the first and second groups (5, 6, 8, 10) of valve cylinder devices having first, second and third valve cylinder devices (13) arranged about and extending outwards with respect to the crankshaft (2), the first and third valve cylinder devices being axially offset from each other, the second valve cylinder device being axially offset from the first and third valve cylinder devices and the second valve cylinder device being offset from the first and third valve cylinder devices about the axis of rotation, wherein the second valve cylinder device has an axial extent which overlaps with the axial extent of one, or the axial extents of both, of the first and third valve cylinder devices.

Abstract: The invention provides a fluid working machine comprising: a crankshaft (2) which is rotatable about an axis of rotation (3); adjacent first and second groups (5, 6, 8, 10) of valve cylinder devices (13) spaced from each other about the axis of rotation (3), one or each of the first and second groups (5, 6, 8, 10) of valve cylinder devices having first, second and third valve cylinder devices (13) arranged about and extending outwards with respect to the crankshaft (2), the first and third valve cylinder devices being axially offset from each other, the second valve cylinder device being axially offset from the first and third valve cylinder devices and the second valve cylinder device being offset from the first and third valve cylinder devices about the axis of rotation, wherein the second valve cylinder device has an axial extent which overlaps with the axial extent of one, or the axial extents of both, of the first and third valve cylinder devices.

Abstract: This invention describes compositions comprising at least 75 mg/mL of solubilized otherwise poorly soluble drug in an aqueous environment, wherein the composition further comprises a combination of 3 or more acids. Methods of providing analgesia, anti-pyretic effects or reducing pain in a subject presenting with a pain condition, and methods of reducing administration site irritation, inflammation or a combination thereof in a subject presenting with a pain condition, comprising the steps of administering such compositions and infusion pumps containing such compositions are also described.

Abstract: A removable seat assembly for a vehicle, including a base assembly having a riser portion configured to support a seat; a frame structure coupled to and supporting the riser portion, the frame structure defining a first generally planar surface configured to support a floor section; a seat dolly coupled to the frame structure, the seat dolly including a plurality of wheels for moving the seat assembly from a first position to a second position; a floor base assembly defining a substantially planar surface for receiving the plurality of wheels of the seat dolly as the seat assembly is moved from the first position to the second position; and a mounting bracket configured to releasably lock the seat dolly to the floor base assembly.

Abstract: A removable seat assembly for a vehicle, including a base assembly having a riser portion configured to support a seat; a frame structure coupled to and supporting the riser portion, the frame structure defining a first generally planar surface configured to support a floor section; a seat dolly coupled to the frame structure, the seat dolly including a plurality of wheels for moving the seat assembly from a first position to a second position; a floor base assembly defining a substantially planar surface for receiving the plurality of wheels of the seat dolly as the seat assembly is moved from the first position to the second position; and a mounting bracket configured to releasably lock the seat dolly to the floor base assembly.