Patents by Inventor Michael Lamsa

Michael Lamsa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 8377675
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: February 19, 2013
    Assignee: Novozymes, Inc.
    Inventors: Suzanne Otani, Debbie Yaver, Haiyan Ge, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
    Publication number: 20130025005
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: August 30, 2012
    Publication date: January 24, 2013
    Applicants: Novozymes A/S, Novozymes, Inc.
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Lipase Variants for Pharmaceutical Use
    Publication number: 20120308543
    Abstract: The pharmaceutical use of lipases related to the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 2, optionally in combination with a protease and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The lipases of the invention have, e.g., an improved digestion performance in vitro, an improved activity at a pH in the neutral range, an improved stability at low pH, an are stable against protease-degradation, and/or are stable in the presence of pepsin and bile salts. The invention also relates to methods of determining digestion performance in vitro of lipases, as well as to certain novel variants of the lipase of T. lanuginosus.
    Type: Application
    Filed: August 16, 2012
    Publication date: December 6, 2012
    Applicants: NOVOZYMES, INC., NOVOZYMES A/S
    Inventors: Allan Svendsen, Michael Skjoet, Deborah Yaver, Lars Lehmann Hylling Christensen, Signe Eskildsen Larsen, Nina Lundin, Michael Lamsa, Peter Colin Gregory
  • Lipase variants for pharmaceutical use
    Patent number: 8273348
    Abstract: The pharmaceutical use of lipases related to the Thermomyces lanuginosus (Humicola lanuginosa) lipase comprising amino acids 1-269 of SEQ ID NO: 2, optionally in combination with a protease and/or an amylase. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The lipases of the invention have, e.g., an improved digestion performance in vitro, an improved activity at a pH in the neutral range, an improved stability at low pH, an are stable against protease-degradation, and/or are stable in the presence of pepsin and bile salts. The invention also relates to methods of determining digestion performance in vitro of lipases, as well as to certain novel variants of the lipase of T. lanuginosus.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: September 25, 2012
    Assignees: Novozymes A/S, Novozymes Inc.
    Inventors: Allan Svendsen, Michael Skjoet, Debbie Yaver, Lars Lehmann Hylling Christensen, Signe Eskildsen Larsen, Nina Lundin, Michael Lamsa, Peter Colin Gregory
  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 8263824
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: September 11, 2012
    Assignees: Novozymes A/S, Novozymes, Inc.
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • POLYPEPTIDES HAVING LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20120192316
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: April 5, 2012
    Publication date: July 26, 2012
    Applicants: Novozymes A/S, Novozymes, Inc.
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Lipase variants
    Patent number: 8187854
    Abstract: The invention provides variant lipases, preferably, variants with reduced tendency to odor generation obtained by introducing mutations in one or more regions identified in a parent lipase.
    Type: Grant
    Filed: January 22, 2007
    Date of Patent: May 29, 2012
    Assignee: Novozymes A/S
    Inventors: Jesper Vind, Jürgen Carsten Franz Knötzel, Kim Borch, Allan Svendsen, Thomas Honger Callisen, Debbie Yaver, Mads Eskelund Bjornvad, Peter Kamp Hansen, Haiyan Ge, Michael Lamsa
  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 8158400
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: April 17, 2012
    Assignees: Novozymes, Inc., Novozymes A/S
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • POLYPEPTIDES HAVING LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20120058930
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: November 10, 2011
    Publication date: March 8, 2012
    Applicants: NOVOZYMES A/S, NOVOZYMES, INC.
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 8067218
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: November 29, 2011
    Assignees: Novozymes, Inc., Novozymes A/S
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • POLYPEPTIDES HAVING LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20110224123
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: May 24, 2011
    Publication date: September 15, 2011
    Applicants: Novozymes, Inc., Novozymes A/S
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Chritopher Amolo, Kim Borch, Shamkant Anant, Michael Lamsa, Barbara Cherry
  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 7955830
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: November 11, 2010
    Date of Patent: June 7, 2011
    Assignees: Novozymes, Inc., Novozymes A/S
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Polypeptides having lipase activity and polynucleotides encoding same
    Publication number: 20110053822
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: November 11, 2010
    Publication date: March 3, 2011
    Applicants: Novozymes, Inc., Novozymes A/S
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 7855172
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: December 21, 2010
    Assignees: Novozymes, Inc., Novozymes A/S
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Polypeptides having lipase activity and polynucleotides encoding same
    Publication number: 20100190680
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: January 29, 2010
    Publication date: July 29, 2010
    Applicants: Novozymes, Inc., Novozymes A/S
    Inventors: Debbie Yaver, Suzanne Otani, Haiyan Ge, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • DETERGENT COMPOSITIONS
    Publication number: 20100162491
    Abstract: The present invention relates to detergent compositions comprising a detergent ingredient and a lipase variant with reduced potential for odor generation obtained by introducing mutations in one or more regions identified in a parent lipase.
    Type: Application
    Filed: March 10, 2010
    Publication date: July 1, 2010
    Inventors: PHILIP FRANK SOUTER, JOHN ALLEN BURDIS, ALLAN SVENDSEN, THOMAS HONGER CALLISEN, JESPER VIND, DEBBIE YAVER, JURGEN CARSTEN FRANZ KNOTZEL, KIM BORCH, MADS ESKELUND BJORNVAD, PETER KAMP HANSEN, MICHAEL LAMSA
  • Polypeptides having lipase activity and polynucleotides encoding same
    Publication number: 20100120654
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: January 14, 2010
    Publication date: May 13, 2010
    Applicants: NOVOZYMES, INC., NOVOZYMES A/S
    Inventors: DEBBIE YAVER, SUZANNE OTANI, JANINE LIN, CHRITOPHER AMOLO, KIM BORCH, SHAMKANT ANANT PATKAR, MICHAEL LAMSA, BARBARA CHERRY
  • Variants of Beta-Glucosidases
    Publication number: 20100099146
    Abstract: The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.
    Type: Application
    Filed: December 16, 2009
    Publication date: April 22, 2010
    Applicant: Novozymes, Inc.
    Inventors: Ana Fidantsef, Michael Lamsa, Brian Gorre Clancy
  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 7666630
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: February 23, 2010
    Assignee: Novozymes, Inc.
    Inventors: Debbie Yaver, Suzanne Otani, Haiyan Ge, Janine Lin, Chritopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
  • Polypeptides having lipase activity and polynucleotides encoding same
    Patent number: 7662602
    Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: February 16, 2010
    Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Chritopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry