Abstract: The present invention provides a solid composition for oral administration comprising: (i) a drug compound; (ii) chitosan or a derivative thereof or a salt of chitosan or salt of a derivative of chitosan; and (iii) an organic acid. Preferably the drug compound is a polar molecule having a molecular weight of 1 KDa or less, a peptide, a protein or a polysaccharide. The compositions of the invention provide enhance absorption of the drug compound.

Abstract: A new and improved adhesive tape dispenser is adapted to dispense tape wound upon a tape core and includes a frame, an application roller, a cutter assembly, and handle mounted on the frame. The adhesive tape dispenser includes a core support assembly secured to the frame and having a first axis. The core support assembly comprises a shaft secured to the frame, and an axle assembly disposed about at least a portion of the shaft. A spindle adapted to support the tape core is rotatably mounted on the axle assembly. The axle assembly includes a hub having an outer surface with a second axis adjacent the first axis, at least one flange extending radially from the hub, and a cam rotatably mounted on the hub. The spindle freely rotates in a first direction. Wherein rotation of the spindle in a second direction rotates the cam about the second axis in the second direction whereby the cam engages the spindle preventing further rotation of the spindle in the second direction about the axle assembly.

Abstract: The present invention provides a solid composition for oral administration comprising: (i) a drug compound; (ii) chitosan or a derivative thereof or a salt of chitosan or salt of a derivative of chitosan; and (iii) an organic acid. Preferably the drug compound is a polar molecule having a molecular weight of 1 KDa or less, a peptide, a protein or a polysaccharide. The compositions of the invention provide enhance absorption of the drug compound.