Patents by Inventor Michael Lein

Michael Lein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150241406
    Abstract: The present invention concerns means and methods for cancer diagnosis and, in particular, diagnosis of prostate cancer. Specifically, it relates to a method for diagnosing whether a subject is at risk for recunent prostate carcinoma after prostatectomy comprising determining the amount of at least one metabolite selected from Table 2 in a test sample of a subject after prostatectomy, and comparing the determined amount to a reference, whereby it is diagnosed whether the subject is at risk for recurrent prostate carcinoma after prostatectomy. Further methods provided in accordance with the present invention relate to differentiating between a malignant prostate carcinoma tissue and a non-malignant tissue and diagnosing metastasizing prostate carcinoma in a subject. Also provided are devices for carrying out the aforementioned methods.
    Type: Application
    Filed: October 2, 2013
    Publication date: August 27, 2015
    Applicants: Charité Universitätsmedizin Berlin, Metanomics Health GmbH
    Inventors: Regina Reszka, Beate Kamlage, Bianca Bethan, Klaus Jung, Michael Lein, Glen Kristiansen, Carsten Stephan
  • Publication number: 20120122243
    Abstract: The present invention relates to a method, preferably an ex vivo method, for diagnosing prostate carcinomas and/or predisposition thereof comprising determining at least one metabolite in a test sample of a subject suspected to suffer from prostate carcinomas or to have a predisposition therefor and comparing said at least one metabolite to a reference, whereby prostate carcinomas or a predisposition therefor is to be diagnosed. Moreover, the present invention encompasses a collection of metabolites, a data collection comprising characteristic values of metabolites and a storage medium comprising said data collection. Furthermore, the present invention also relates to a system comprising means for comparing characteristic values of metabolites of a sample operatively linked to a data storage medium.
    Type: Application
    Filed: June 2, 2010
    Publication date: May 17, 2012
    Applicants: CHARITE UNIVERSITATSMEDIZIN BERLIN, METANOMICS HEALTH GMBH
    Inventors: Beate Kamlage, Bianca Bethan, Regina Reszka, Edgar Leibold, Klaus Jung, Michael Lein, Glen Kristiansen
  • Patent number: 7149988
    Abstract: Power plane structures that may generate high E-fields can be identified and flagged for additional review by representing a boundary of the structures as a function, and evaluating the second derivative of that function. The result can be compared against a threshold value to determine if further review of the structure is desirable.
    Type: Grant
    Filed: January 26, 2005
    Date of Patent: December 12, 2006
    Assignee: Dell Products L.P.
    Inventor: Michael Leins
  • Publication number: 20060190855
    Abstract: Power plane structures that may generate high E-fields can be identified and flagged for additional review by representing a boundary of the structures as a function, and evaluating the second derivative of that function. The result can be compared against a threshold value to determine if further review of the structure is desirable.
    Type: Application
    Filed: January 26, 2005
    Publication date: August 24, 2006
    Applicant: Dell Products L.P.
    Inventor: Michael Leins
  • Publication number: 20060020046
    Abstract: The invention is concerned with the use of lycopene, optionally in combination with vitamin E and/or C or other biologically active ingredients as disclosed in the specification, in the manufacture of a composition for the primary and secondary prevention of angiogenesis-associated pathologies and coadjuvant treatment thereof; as well as with particular novel formulations comprising lycopene.
    Type: Application
    Filed: February 6, 2003
    Publication date: January 26, 2006
    Applicant: DMS IP ASSETS B.V.
    Inventors: Regina Goralczyk, Klaus Jung, Michael Lein, Luca Barella, Ulrich Siler, Elisabeth Stocklin, Karin Wertz
  • Patent number: 6978333
    Abstract: A method and system are provided for reducing impedance discontinuities which occur when two expansion connectors are located very close to one another on a bus in an information handling system. An interconnect is situated between the two expansion connectors and exhibits an impedance which is selected to be sufficiently low to compensate for the amount by which the impedance of the expansion bus connectors exceeds the impedance of the expansion bus connected thereto.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: December 20, 2005
    Assignee: Dell Products L.P.
    Inventors: Ian Timmins, Michael Leins, Stuart Hayes, Robert Bassman
  • Publication number: 20050130501
    Abstract: A method and system are provided for reducing impedance discontinuities which occur when two expansion connectors are located very close to one another on a bus in an information handling system. An interconnect is situated between the two expansion connectors and exhibits an impedance which is selected to be sufficiently low to compensate for the amount by which the impedance of the expansion bus connectors exceeds the impedance of the expansion bus connected thereto.
    Type: Application
    Filed: February 1, 2005
    Publication date: June 16, 2005
    Applicant: Dell Products L.P.
    Inventors: Ian Timmins, Michael Leins, Stuart Hayes, Robert Bassman
  • Patent number: 6868467
    Abstract: A method and apparatus are provided for reducing impedance discontinuities which occur when two expansion connectors are located very close to one another on a bus in an information handling system. An interconnect is situated between the two expansion connectors and exhibits an impedance which is selected to be sufficiently low to compensate for the amount by which the impedance of the expansion bus connectors exceeds the impedance of the expansion bus connected thereto.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: March 15, 2005
    Assignee: Dell Products L.P.
    Inventors: Ian Timmins, Michael Leins, Stuart Hayes, Robert Bassman
  • Publication number: 20050001649
    Abstract: A method and apparatus are provided for reducing impedance discontinuities which occur when two expansion connectors are located very close to one another on a bus in an information handling system. An interconnect is situated between the two expansion connectors and exhibits an impedance which is selected to be sufficiently low to compensate for the amount by which the impedance of the expansion bus connectors exceeds the impedance of the expansion bus connected thereto.
    Type: Application
    Filed: July 3, 2003
    Publication date: January 6, 2005
    Applicant: Dell Products L.P.
    Inventors: Ian Timmins, Michael Leins, Stuart Hayes, Robert Bassman