Patents by Inventor Michael Leo West

Michael Leo West has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120220759
    Abstract: Preparation and use of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides for use in the preparation of synthetic heparinoids.
    Type: Application
    Filed: December 14, 2011
    Publication date: August 30, 2012
    Applicant: Alchemia Limited
    Inventors: Joachim SEIFERT, Latika SINGH, Tracie Elizabeth RAMSDALE, Michael Leo WEST, Nicholas Barry DRINNAN
  • Publication number: 20120208993
    Abstract: Preparation and use of synthetic trisaccharides useful for the preparation of synthetic heparinoids.
    Type: Application
    Filed: December 14, 2011
    Publication date: August 16, 2012
    Applicant: Alchemia Limited
    Inventors: Joachim SEIFERT, Latika SINGH, Tracie Elizabeth RAMSDALE, Michael Leo WEST, Nicholas Barry DRINNAN
  • Patent number: 8093227
    Abstract: A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: January 10, 2012
    Assignee: Alchemia Pty Ltd
    Inventors: Michael Leo West, Wim Meutermans, George Adamson, Karl Schafer, Darren Schliebs
  • Publication number: 20100184607
    Abstract: A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I.
    Type: Application
    Filed: August 1, 2008
    Publication date: July 22, 2010
    Applicant: Alchemia Pty Ltd.
    Inventors: Michael Leo West, Wim Meutermans, George Adamson, Karl Schafer, Darren Schliers
  • Patent number: 7737287
    Abstract: This invention relates to combinatorial libraries of potentially biologically active mainly monosaccharide compounds and to methods of preparing same. These compounds are variously functionalized, with a view to varying lipid solubility, size, function and other properties, with the particular aim of discovering a drug or drug-like compound, or compounds with useful properties. The invention provides intermediates, processes and synthetic strategies for the solution or solid phase synthesis of monosaccharides, variously functionalized about the sugar ring, including the addition of aromaticity and charge, and the placement of amino acid and peptide side chain units of isosteres thereof.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: June 15, 2010
    Assignee: Alchemia Limited
    Inventors: Wim Meutermans, Michael Leo West, Thanh Le Giang, George Adamson, Karl Schafer, Giovanni Abbenante
  • Publication number: 20090187013
    Abstract: Preparation of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides for use in the preparation of synthetic heparinoids.
    Type: Application
    Filed: January 15, 2009
    Publication date: July 23, 2009
    Applicant: Alchemia Limited
    Inventors: Joachim SEIFERT, Latika Singh, Tracie Elizabeth Ramsdale, Michael Leo West, Nicholas Barry Drinnan
  • Patent number: 7417129
    Abstract: A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: August 26, 2008
    Assignee: Alchemia Pty Ltd
    Inventors: Michael Leo West, Wim Meutermans, George Adamson, Karl Schafer, Darren Schliebs
  • Publication number: 20050245746
    Abstract: A compound of formula (I), wherein, n is 0 or 1; R6 and R7 are hydrogen, or together form a carbonyl oxygen; R1 is selected from the group consisting of hydrogen; —N(Z)Y and —C(Z)Y wherein; when R1 is —N(Z)Y, then: Y is selected from hydrogen, or the following, where G denotes the point of connection to the nitrogen atom in N(Y)Z (i-v); Z is selected from hydrogen or X1; Q is selected from hydrogen or W; the groups W are independently selected from the group consisting of alkyl, alkenyl, alkynyl, heteroalkyl, aryl, heteroaryl, arylalkyl and heteroarylalkyl of 1 to 20 atoms, the groups X1 are independently selected from the group consisting of alkyl, alkenyl, alkynyl, heteroalkyl, acyl, arylacyl, heteroarylacyl, aryl, heteroaryl, arylalkyl and heteroarylalkyl of 1 to 20 atoms, when R1 is —C(Z)Y, then: Y is selected from the group consisting of two hydrogen atoms, a double bonded oxygen to form a carbonyl, and a triple bonded nitrogen to form a nitrile, Z is absent, or is selected from hydrogen or U, wherei
    Type: Application
    Filed: March 28, 2003
    Publication date: November 3, 2005
    Inventors: Wim Meutermans, Michael Leo West, Thanh Giang, George Adamson, Karl Schafer, Giovanni Abbenante
  • Publication number: 20040058888
    Abstract: This invention relates to reagents and methods for synthesis of biologically active di- and tri-saccharides comprising &agr;-D-Gal(1→3)-D-Gal. In particular the invention provides novel reagents, intermediates and processes for the solution or solid phase synthesis of &agr;-D-galactopyranosyl-(1→3)-D-galactose, and derivatives thereof. In one preferred embodiments the invention provides a protected monosaccharide building block of general formula (II): in which R3 is methoxy or methyl; R1 is H, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4-chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl; and R2 is H, Fmoc, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4-chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl.
    Type: Application
    Filed: December 11, 2002
    Publication date: March 25, 2004
    Inventors: Laurent Bornaghi, Gyula Dekany, Nicholas Barry Drinnan, John Papageorgiou, Michael Leo West
  • Publication number: 20030232766
    Abstract: A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I.
    Type: Application
    Filed: April 17, 2003
    Publication date: December 18, 2003
    Inventors: Michael Leo West, Wim Meutermans, George Adamson, Karl Schafer, Darren Schliebs
  • Patent number: 5723631
    Abstract: The present invention relates to a process for the preparation of a compound of the following structure: ##STR1## wherein, substituents are as defined in the specification.
    Type: Grant
    Filed: June 22, 1995
    Date of Patent: March 3, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Ashok Dharmaji Patil, Robert Philip Hertzberg, Geoffrey B. Dreyer, Alan James Freyer, John W. Westley, Balan Chenera, Michael Leo West