Patents by Inventor Michael LeRoy Phillips

Michael LeRoy Phillips has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole sPLA2 inhibitors
    Patent number: 7026348
    Abstract: A class of novel acylsulfonamide substituted indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of inflammatory diseases such as septic shock.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: April 11, 2006
    Assignee: Eli Lilly and Company
    Inventors: Edward David Mihelich, Michael LeRoy Phillips, Alan M Warshawsky
  • Substituted tricyclics
    Patent number: 6713645
    Abstract: A class of novel tricyclics is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: March 30, 2004
    Assignee: Eli Lilly and Company
    Inventors: Nicholas James Bach, Susan Elizabeth Draheim, Robert Delane Dillard, Edward David Mihelich, Jason Scott Sawyer, Douglas Wade Beight, Michael LeRoy Phillips, Tulio Suarez, Daniel Jon Sall, Jolie Anne Bastian, Michael Lyle Denney, Gary Alan Hite, Michael Dean Kinnick, Robert Theodore Vasileff, John Michael Morin, Jr., Ho-Shen Lin, Michael Enrico Richett, Richard Waltz Harper, John McNeill McGill, III, Benjamin Alan Anderson, Nancy Kay Harn, Richard James Loncharich, Richard Walter Schevitz
  • Indole sPLA2 inhibitors
    Publication number: 20030191175
    Abstract: A class of novel acylsulfonaimide substituted indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of inflammatory diseases such as septic shock.
    Type: Application
    Filed: March 21, 2003
    Publication date: October 9, 2003
    Inventors: Edward David Mihelich, Michael LeRoy Phillips, Alan M. Warshawsky
  • Indole sPLA2 inhibitors
    Patent number: 6608099
    Abstract: A class of novel acylsulfonamide substituted indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of inflammatory diseases.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: August 19, 2003
    Assignee: Eli Lilly and Company
    Inventors: Edward David Mihelich, Michael LeRoy Phillips, Alan M Warshawsky
  • Methods of using novel compounds as neuro-protective agents
    Patent number: 6579871
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: June 17, 2003
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • Methods of using novel compounds as neuro-protective agents
    Publication number: 20030050311
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: September 3, 2002
    Publication date: March 13, 2003
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, David Lee Varie
  • Novel compounds useful as neuro-protective agents
    Publication number: 20020177595
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: March 27, 2002
    Publication date: November 28, 2002
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, David Lee Varie
  • Methods of using compounds as neuro-protective agents
    Patent number: 6472387
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: October 29, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • Compounds useful as neuro-protective agents
    Patent number: 6448396
    Abstract: The present invention provides a process of preparing a compound of the formula IV wherein: R1 and R2 are each individually -(C1-C6)alkyl, -(C1-C6)alkoxy or phenyl, R3 is H or -(C1-C6)alkyl, R6 is —NR7R8, morpholin-1-yl, imidazol-1-yl, 4,5-dihydro-1H-imidazol-2-yl, thiomorpholin-1-yl, piperazin-1-yl or piperazin-1-yl substituted with -(C1-C4)alkyl or  and R7 and R8 are each individually hydrogen, -(C1-C6)alkyl, —(CH2)pOH,  —(CH2)p-piperidyl, —(CH2)pS(C1-C6)alkyl, —(CH2)pO(C1-C6)alkyl  where R9 is (C1-C6)alkyl; P is an integer from 1-3 both inclusive; q is 0 or 1; and t is 1 to 6 both inclusive; or a pharmaceutically acceptable salt, hydrate or optical isomer thereof, which is useful as a neuroprotective agent.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: September 10, 2002
    Assignee: Eli Lilly and Company
    Inventors: Benjamin Alan Anderson, Lawrence Joseph Heinz, Jill Ann Panetta, Michael LeRoy Phillips, John Allan Rieck, III, John Robert Rizzo, John Kevin Shadle, David Lee Varie
  • Methods of using novel compounds as neuro-protective agents
    Patent number: 6423709
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: July 23, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • METHODS OF USING NOVEL COMPOUNDS AS NEURO-PROTECTIVE AGENTS
    Publication number: 20020065274
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: November 28, 2001
    Publication date: May 30, 2002
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck,, David Lee Varie
  • Compounds useful as neuro-protective agents
    Patent number: 6380213
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: April 30, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS
    Publication number: 20010027194
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: September 23, 1998
    Publication date: October 4, 2001
    Inventors: BENJAMIN ALAN ANDERSON, LAWRENCE JOSEPH HEINZ, JILL ANN PANETTA, MICHAEL LEROY PHILLIPS, JOHN ALLAN RIECK, JOHN ROBERT RIZZO, JOHN KEVIN SHADLE, DAVID LEE VARIE
  • Substituted tricyclics
    Patent number: 6177440
    Abstract: A class of novel tricyclics is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: January 23, 2001
    Assignee: Eli Lilly and Company
    Inventors: Nicholas James Bach, Susan Elizabeth Draheim, Robert Delane Dillard, Edward David Mihelich, Jason Scott Sawyer, Douglas Wade Beight, Michael LeRoy Phillips, Tulio Suarez, Daniel Jon Sall, Jolie Anne Bastian, Michael Lyle Denney, Gary Alan Hite, Michael Dean Kinnick, Robert Theodore Vasileff, John Michael Morin, Jr., Ho-Shen Lin, Michael Enrico Richett, Richard Waltz Harper, John McNeill McGill, III, Benjamin Alan Anderson, Nancy Kay Harn, Richard James Loncharich, Richard Walter Schevitz
  • Compounds useful as neuro-protective agents
    Patent number: 6166216
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: December 26, 2000
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • Compounds useful as neuro-protective agents
    Patent number: 6156748
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: December 5, 2000
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie