Patents by Inventor Michael LETOURNEAU

Michael LETOURNEAU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of O-demethylation
    Patent number: 11136331
    Abstract: There is provided a novel process for the preparation of a compound of formula I, wherein R1, R2, W, Z and are as described in the description, by demethylation of a corresponding O-methyl derivative with a borohydride-based reagent. This process may be used in the preparation of buprenorphine.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: October 5, 2021
    Assignee: CAMBREX CHARLES CITY, INC.
    Inventors: Par Holmberg, Lars Eklund, David Adams, Michael Letourneau, Margus Eek, Alo Soone
  • NEW PROCESS
    Publication number: 20210188862
    Abstract: There is provided a novel process for the preparation of a compound of formula I, wherein R1, R2, W, Z and are as described in the description, by demethylation of a corresponding O-methyl derivative with a borohydride-based reagent. This process may be used in the preparation of buprenorphine.
    Type: Application
    Filed: October 12, 2018
    Publication date: June 24, 2021
    Inventors: Par HOLMBERG, Lars EKLUND, David ADAMS, Michael LETOURNEAU, Margus EEK, Alo SOONE