Abstract: A method of forming a security device includes: a holographic image layer, diffusion element, and barrier layer. A region of the barrier layer includes a heat-transformable material. The method further includes selectively applying heat at a plurality of positions within the region of the barrier layer, in accordance with a predetermined pattern, so as to modify the heat-transformable material such that the region of the barrier layer is selectively rendered passable to the diffusible substance at each of the plurality of positions, thereby permitting diffusion of the diffusible substance between the regions of the diffusion element and the holographic image layer such that, at a plurality of positions within the region of the holographic image layer and corresponding to the predetermined pattern, the volume hologram is dimensionally modified so as to become viewable in a second observable colour, different from the first observable colour.

Abstract: Techniques are provided herein for increased processing efficiencies in the end-to-end creative offering process. Namely, a uniform ingest process for creative assets yields uniformity across creative providers. Further, centralized ingest of campaign information and creative assets bridges independent systems involved in the creative offering process. In this manner, creative processing tasks, from creative ingest and quality control, to activation with the ad decisioning service and active creative/campaign reporting may be facilitated by a uniform central source of truth. This may result in increased processing efficiencies and reduced processing delay in offering creative assets, which, in turn, may increase revenues generated from the offered creative assets.

Abstract: Disclosed are engineered multicellular organisms. The disclosed organisms comprise an aggregate of ciliated cells, and the organisms move when the ciliated cells are actuated. The engineered multicellular organisms also are capable of kinematic self-replication. The engineered multicellular organisms are capable of moving a plurality of dissociated ciliated cells into piles of ciliated cells which form a multicellular organism comprising an aggregate of ciliated cells which moves when the ciliated cells are actuated. Also disclosed are systems and methods for designing, preparing, and utilizing the engineered multicellular organisms.

Abstract: A method of identifying a subject having Kawasaki disease (KD), which includes discriminating the subject from a subject having another condition, for example other infectious and inflammatory conditions, such as those that present similar symptoms to KD. Also provided is a minimal gene signature employed in the method, as well as primers, probes and gene chips for use in the method.

Abstract: Various embodiments comprise systems, methods, and apparatus for enabling dynamic configuration of devices using encumbered shared spectrum (e.g., CBSDs using CBRS) so as to operate these devices in accordance with a most preferred operator preference of a plurality of operator preferences currently available in view of current wireless operating conditions, such as impacted by overlapping/proximate incumbent or priority users of the shared spectrum, or other changes in spectrum available conditions. Various embodiments further provide for an efficient return of these devices to a most preferred operator preference or steady-state configuration.

Abstract: Disclosed are methods and compositions for treating cell proliferative diseases and disorders including cancers such as glioblastoma. The disclosed methods and compositions may utilize or comprise one or more modulators of the bioelectric state of cells, such as, one or more potassium channel activators; a sodium channel inhibitor combined with an mTOR inhibitor; a sodium channel inhibitor combined with a proton pump inhibitor; a calcium channel inhibitor combined with an mTOR inhibitor; a proton pump inhibitor combined with an alkylating agent; or a combination of at least one potassium channel activator and one or more of an alkylating agent, calcium channel inhibitor, corticosteroid, mTOR inhibitor, proton pump inhibitor, and/or sodium channel inhibitor.

Abstract: Disclosed are engineered multicellular organisms. The disclosed organisms comprise an aggregate of ciliated cells, and the organisms move when the ciliated cells are actuated. The engineered multicellular organisms also are capable of kinematic self-replication. The engineered multicellular organisms are capable of moving a plurality of dissociated ciliated cells into piles of ciliated cells which form a multicellular organism comprising an aggregate of ciliated cells which moves when the ciliated cells are actuated. Also disclosed are systems and methods for designing, preparing, and utilizing the engineered multicellular organisms.

Abstract: The present disclosure provides compositions and methods for treating neurodevelopmental disorders, such as Rett syndrome and cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder.

Abstract: An annuloplasty implant is assembled at a valve of a heart of a subject by (1) transfemorally delivering, to the heart, a first subunit of the implant; and securing the first subunit to tissue of the heart by driving, into the tissue, a first anchor connected to the subunit by a flexible strip; and (2) subsequently, for multiple successive subunits of the implant, iteratively: (a) transfemorally delivering, to the heart, the successive subunit; and (b) securing the successive subunit to the tissue of the heart by driving, into the tissue, a respective anchor connected to the successive subunit by a respective flexible strip. The annuloplasty implant is subsequently contracted to contract the valve. Other embodiments are also described.

Abstract: Various embodiments comprise systems, methods, and apparatus for enabling dynamic configuration of devices using encumbered shared spectrum (e.g., CBSDs using CBRS) so as to operate these devices in accordance with a most preferred operator preference of a plurality of operator preferences currently available in view of current wireless operating conditions, such as impacted by overlapping/proximate incumbent or priority users of the shared spectrum, or other changes in spectrum available conditions. Various embodiments further provide for an efficient return of these devices to a most preferred operator preference or steady-state configuration.

Abstract: An implant, disposed within a catheter, comprises a ring, anchors, and adjustment elements. The ring comprises struts arranged in a pattern of alternating peaks and troughs. Each strut has a first end-portion and a second end-portion. Each peak is defined by convergence of adjacent first end-portions disposed at an angle with respect to each other, and each trough is defined by convergence of adjacent second end-portions. Each of the anchors has a longitudinal axis, is coupled to the ring at a respective trough, and is configured to be driven along the longitudinal axis with respect to the trough and into tissue of the heart. Each of the adjustment elements is configured to adjust an angular disposition between a respective pair of the struts. A first adjustment element is coupled to its pair, and a second adjustment element is coupled to its pair distal to the first adjustment element.

Abstract: Described embodiments include an apparatus that includes an expandable structure, configured for insertion into a body of a subject, and a plurality of conducting elements coupled to the expandable structure. Each of the conducting elements comprises a respective coil and has an insulated portion that is electrically insulated from tissue of the subject, and an uninsulated portion configured to exchange signals with the tissue, while in contact with the tissue. Other embodiments are also described.

Abstract: A system includes a signal generator, configured to pass a generated signal, which has two different generated frequencies, through a circuit including a bidirectional semiconductor device. The system further includes a processor, configured to identify, while the generated signal is passed through the circuit, a derived frequency, which derives from the generated frequencies, on the circuit, and to generate, in response to identifying the derived frequency, an output indicating that a property of the bidirectional semiconductor device is asymmetric. Other embodiments are also described.

Abstract: Described embodiments include an apparatus that includes an expandable structure, configured for insertion into a body of a subject, and a plurality of conducting elements coupled to the expandable structure. Each of the conducting elements comprises a respective coil and has an insulated portion that is electrically insulated from tissue of the subject, and an uninsulated portion configured to exchange signals with the tissue, while in contact with the tissue. Other embodiments are also described.

Abstract: A method and system are directed to designing a low-dropout regulator (LDO) circuit and using the LDO circuit to detect recycled counterfeit integrated circuits. The LDO circuit includes, in part, a reference path circuit and a stressed path circuit. Each of the reference path circuit and the stressed path circuit is coupled to a control signal that can enable the corresponding path circuit for the LDO. LDO parameters can then be measured while the reference path circuit and the stressed path circuit is enabled respectively. The difference between the LDO parameters measured while the reference path circuit is enabled and while the stressed path circuit is enabled is used to determine if an integrated circuit comprising the LDO circuit is a recycled counterfeit.

Abstract: According to at least one embodiment, one or more potential advertisement slots may be identified based on contextual characteristics relating to content. Such contextual characteristics may include tonality, sentiment and/or data that places potentially worrisome content in context. By identifying potential advertisement slots based on such characteristics, a seller develops a better understanding of content running on its own media platform(s), builds a greater level of trust with its advertiser partners, and generates better yield with respect to its advertisement inventory.

Abstract: In one embodiment, a medical system includes a catheter interface comprising electrode lines configured to be electrically connected to respective electrodes of a catheter, and a signal generation apparatus configured to generate signal pulses, each of the signal pulses comprising a carrier frequency and having a non-rectangular signal envelope, the signal generation apparatus being configured to time multiplex the signal pulses among the electrode lines.

Abstract: Systems and methods are provided for storing a first data object comprising a first set of immutable components, the first data object being associated with a corresponding second data object stored by a remote replication system. A difference is determined between the first set of immutable components of the first data object and a second set of immutable components of the corresponding second data object. A subset of immutable components is identified from the first set of immutable components based on the difference. The subset of immutable components from the first set of immutable components is provided to the remote replication system over a communication network.

Abstract: Disclosed are engineered multicellular organisms. Also disclosed are systems and methods for designing, preparing, and utilizing the engineered multicellular organisms including methods of modulating tissue formulation and healing.

Abstract: A plurality of control-signal generators are configured to generate respective control signals having respective control-signal amplitudes and different respective control-signal frequencies, and a plurality of signal adders are configured to produce respective composite signals for application to a subject, by adding the control signals to respective ablation signals having respective ablation-signal amplitudes. The control-signal generators are configured to generate the control signals such that respective ratios between the control-signal amplitudes and the ablation-signal amplitudes are constant during the application of the composite signals to the subject.