Patents by Inventor Michael Ligotke
Michael Ligotke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7958890Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.Type: GrantFiled: December 4, 2008Date of Patent: June 14, 2011Assignee: Quadrant Technologies LimitedInventors: Andrew W. Gieschen, Michael Ligotke, Jeffrey Chen, Charles F. Ganem, Bernard Greenspan
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Publication number: 20090084380Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.Type: ApplicationFiled: December 4, 2008Publication date: April 2, 2009Inventors: Andrew W. Gieschen, Michael Ligotke, Jeffrey Chen, Charles F. Ganem, Bemard Greenspan
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Patent number: 7069929Abstract: A dry powder inhaler includes an actuator pivotably mounted on a base. Movement of the actuator from a first position to a second position drives the a dobber to open a blister. A dispersion engine sub-assembly has a blister hood positioned over a blister opening position. A powder pathway connects from the blister hood into a powder dispersion engine. Upon inhalation, air flow draws powder up and out of an opened blister, into the blister hood and to the powder dispersion engine. Movement of the actuator causes the dobber to shear open a blister and also to press the blister hood down over the blister. This increases air flows up and around the open blister, carrying the pharmaceutical powder up and out of the blister and into the dispersion engine.Type: GrantFiled: March 15, 2002Date of Patent: July 4, 2006Assignee: Quadrant Technologies LimitedInventors: Matthew Young, Stuart Kay, Neil Harrison, James Welsh, Michael Ligotke
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Publication number: 20060005833Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.Type: ApplicationFiled: September 12, 2005Publication date: January 12, 2006Inventors: Andrew Gieschen, Michael Ligotke, Jeffrey Chen, Charles Ganem, Bernard Greenspan
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Publication number: 20050284473Abstract: A unit dose dry powder inhaler includes a chamber housing containing a powder dispersion chamber. A chamber tube extends from the dispersion chamber into the mouthpiece. A cover or cup is rotatably attached to the chamber housing. A dose of a dry powder is contained at a powder location in the chamber housing. An air passageway leading from the powder location to the dispersion chamber is closed off by the cover. When the cover is rotated to an open position, the air passageway is opened. The user inhales on the mouthpiece drawing air through the powder location, the air passageway, the dispersion chamber and the chamber tube, through the mouthpiece and into the users lungs. The unit dose of dry powder is stored directly in, or is part of, the inhaler.Type: ApplicationFiled: May 17, 2005Publication date: December 29, 2005Inventors: Matthew Young, Stuart Brian Kay, Neil Harrison, Michael Ligotke
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Patent number: 6971384Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.Type: GrantFiled: February 19, 2004Date of Patent: December 6, 2005Assignee: Quadrant Technologies LimitedInventors: Andrew W. Gieschen, Michael Ligotke, Jeffrey Chen, Charles Ganem, Bernard Greenspan
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Publication number: 20050263153Abstract: A unit dose dry powder inhaler has a dose unit within an inhaler housing. As the dose unit is pushed into the inhaler housing, a container on the dose unit is opened, releasing a pharmaceutical powder into the housing. The user inhales on a mouthpiece, drawing the powder and air into a dispersion chamber. The powder disperses in air, and the powder/air mixture is inhaled. The inhaler is inexpensive, compact, and simple to use.Type: ApplicationFiled: May 17, 2005Publication date: December 1, 2005Inventors: Matthew Young, Stuart Brian Kay, Neil Harrison, Michael Ligotke
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Publication number: 20040163644Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater airflow and powder dispersion, without any increased effort by the patient.Type: ApplicationFiled: February 19, 2004Publication date: August 26, 2004Inventors: Andrew W. Gieschen, Michael Ligotke, Jeffrey Chen, Charles F. Ganem, Bernard Greenspan
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Patent number: 6715486Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from the larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater air flow and powder dispersion, without any increased effort by the patient.Type: GrantFiled: January 31, 2001Date of Patent: April 6, 2004Assignee: Quadrant Technologies LimitedInventors: Andrew W. Gieschen, Michael Ligotke, Jeffrey Chen, Charles Ganem, Bernard Greenspan
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Publication number: 20020170560Abstract: A dry powder inhaler for providing multiple doses of a pharmaceutical powder from blisters on a blister disk includes an actuator pivotably mounted on a base. Movement of the actuator from a first position to a second position drives the a dobber to open a blister. A tray retainer is moveable between opened and closed positions, and the actuator is moveable to a position at least partially overlying the tray retainer, when the tray retainer is in the closed position. A dispersion engine sub-assembly has a blister hood positioned over a blister opening position. A powder pathway connects from the blister hood into a powder dispersion engine. Upon inhalation, air flow draws powder up and out of an opened blister, into the blister hood and to the powder dispersion engine. Movement of the actuator causes the dobber to shear open a blister on a blister disk, and also to press the blister hood down over, or into contact with blister disk.Type: ApplicationFiled: March 15, 2002Publication date: November 21, 2002Applicant: ELAN PHARMACEUTICALS, INC.Inventors: Matthew E. Young, Stuart B.W. Kay, Neil R. Harrison, Janes Welsh, Michael Ligotke
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Patent number: 6427688Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from the larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater air flow and powder dispersion, without any increased effort by the patient.Type: GrantFiled: February 1, 2000Date of Patent: August 6, 2002Assignee: Dura Pharmaceuticals, Icn.Inventors: Michael Ligotke, Andrew W. Gieschen, Robert F. Eisele, Thomas R. Jackson, Jeffrey Chen, Bernard Greenspan, Clyde Witham, Gary Ward
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Publication number: 20010027790Abstract: A dry powder inhaler has a dispersion chamber containing beads. A dose of dry powder is released into the chamber, or into an inlet tangentially joining into the chamber. As the patient inhales on a nosepiece or mouthpiece, air moves circularly through the dispersion chamber to drive the beads. The beads roll, bounce, and collide repeatedly with the drug particles on the chamber surfaces or on the beads. The smaller active drug particles are separated from the larger carrier particles and from each other, and a powder aerosol is created and inhaled by the patient. The beads are preferably lightweight, so that they can be rapidly accelerated and moved, even with nominal inspiration. The flow resistance of the inhaler is also reduced via the beads, allowing greater air flow and powder dispersion, without any increased effort by the patient.Type: ApplicationFiled: January 31, 2001Publication date: October 11, 2001Applicant: Dura Pharmaceuticals, Inc.Inventors: Andrew W. Gieschen, Michael Ligotke, Jeffrey Chen, Charles F. Ganem, Bernard Greenspan