Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed to determine unique audience size via clustered data. An example apparatus includes memory, machine readable instructions, and processor circuitry to at least one of execute or instantiate the machine readable instructions. The example processor circuitry is to form a first matrix identifying matching and non-matching instances of first values of respective demographics of an audience of media and second values of the respective demographics. Also, the processor circuitry is to normalize the first matrix to generate an account sharing adjustment matrix. Additionally, the processor circuitry is to apply the account sharing adjustment matrix to a vector of one or more counts of impressions of the media to correct for one or more members of the audience that share a user account registered with a database proprietor, the one or more counts of the impressions corresponding to the respective demographics.

Abstract: A casing or case assembly for a mobile communications device case provides a primary device-receiving body formation. At the posterior portions of the primary device-receiving body formation is an accessory access window. The accessory access window is configured to allow a user to interface a charging device with the mobile communications device as received in the primary device-receiving body formation in anterior adjacency to an optional posterior panel portion. The accessory access window is of sufficient dimension to receive a charger device with a device diameter that fits within the window. A number of accessories, in addition to a charger device, are attachable to the mobile communications device via the accessory access window. Certain exemplary accessories include a cover panel, a wallet accessory, and a vehicular mount mechanism. At least one secondary body formation may be affixed to the primary device-receiving body formation as an outer skin thereof.

Abstract: Provided herein are gel, ointment, lotion, or cream formulations including an active pharmaceutical ingredient that includes a tropanyl moiety. The gel, lotion or cream formulations may include at least one low molecular weight (LMW) compound or a pharmaceutically acceptable salt thereof. Also provided herein are gel, ointment, lotion, or cream formulations including an active pharmaceutical agent such as atropine, pilocarpine, physostigmine, or travoprost.

Abstract: A digital power converter arrangement of an electric vehicle includes a CPU circuit and a function selection circuit. The CPU circuit is configured to execute and perform analog and digital conversion, pulse-width modulation and communication, including a CPU outputting one or more PWM signals by changing a time ratio of a turn-on/turn-off of square wave pulse width modulation signals. The function selection circuit includes a function selector switch configured to switch between an external battery charging function mode, an AC power supply output function mode, and an external motor driver function mode, and a motor selector switch configured to function a motor hall mode when the function selector switch is switched to the external motor driver function mode, wherein the CPU detects the function selector switch and motor selector switch to switch states to run corresponding functions.

Abstract: A system can receive data relating to a tubular of a well system. The system can execute a first module to determine first outputs. The system can execute a second module to determine second outputs based on the first outputs. The system can execute a third module to determine third outputs based on the first outputs. The second outputs can include a crack-initiation fracture pressure, and the third outputs can include a crack-propagation fracture pressure. The system can identify a brittle-burst strength of the tubular from among the second outputs, the third outputs, and a standard burst strength of the tubular. The system can provide the brittle-burst strength of the tubular to facilitate an adjustment to the tubular to optimize a wellbore operation associated with the well system.

Abstract: A system can receive data relating to a tubular of a well system. The system can execute a first module to determine first outputs. The system can execute a second module to determine second outputs based on the first outputs. The system can execute a third module to determine third outputs based on the first outputs. The second outputs can include a crack-initiation fracture pressure, and the third outputs can include a crack-propagation fracture pressure. The system can identify a brittle-burst strength of the tubular from among the second outputs, the third outputs, and a standard burst strength of the tubular. The system can provide the brittle-burst strength of the tubular to facilitate an adjustment to the tubular to optimize a wellbore operation associated with the well system.

Abstract: Described herein are formulations including pharmaceutical agents comprising ester and/or lactone ring structures, and methods of using the same. The invention is also directed to a method and ophthalmic pharmaceutical compositions including solution and semisolid dosage forms (i.e. ophthalmic creams, gels, lotions, serums, and/or ointments) of treating a patient with various ocular diseases including presbyopia and dry eyes. The method comprising instructing a patient to apply one strip of the ophthalmic composition to the eyelids that includes pilocarpine or other active pharmaceutical ingredients containing ester and/or lactone ring structures with and without the buffering system.

Abstract: A system can generate, via a software model, downhole pressure estimations and downhole debris estimations using caving parameters. Additionally, the system can generate, via the software model, settled caving volume percent estimations using the caving parameters. The system can determine a pack off volume percent using the downhole pressure estimations, the downhole debris estimations, and the settled caving volume percent estimations. The system can output, via a user interface, the pack off indicator and a subset of the caving parameters for use in adjusting a wellbore operation. The user interface can provide a plot of the pack off volume percent horizontally offset with respect to a plot of the subset of the caving parameters and a depth of the wellbore.

Abstract: The present disclosure relates to the technical field of medical instrument and provides a passage establishment device for posterior spinal fusion minimally invasive surgery. The device includes: a tube, an interior of the tube includes a through hole penetrating through both axial ends of the tube, and a wall of the tube includes an opening portion. The tube of the passage establishment device of the present disclosure can be inserted between the vertebral bodies and can also be removed from between the vertebral bodies. The through hole of the tube forms a surgical passage for the fusion device to penetrate, which can safely protect human tissues and is convenient for doctors to perform follow-up operations. The tube can be installed quickly, and thus the operation time is shortened. It is easy to disassemble, clean, and disinfect the tube.

Abstract: A method for controlling computerized operations related to a wellbore comprises drilling the wellbore in a subsurface formation with a drill string including a drill bit. The method comprises acquiring a plurality of drilling parameters while drilling the wellbore. The method comprises determining, based on the plurality of drilling parameters, solids properties for solids forming a cutting plug up hole of the drill bit. The method comprises determining a length of the cutting plug based on the solids properties. The method comprises determining a cutting plug friction force based on the cutting plug length and a pressure differential across the cutting plug. The method comprises performing a drilling operation based on the cutting plug friction force.

Abstract: A method for controlling computerized operations related to a wellbore comprises drilling the wellbore in a subsurface formation with a drill string including a drill bit. The method comprises acquiring a plurality of drilling parameters while drilling the wellbore. The method comprises determining, based on the plurality of drilling parameters, solids properties for solids forming a cutting plug up hole of the drill bit. The method comprises determining a length of the cutting plug based on the solids properties. The method comprises determining a cutting plug friction force based on the cutting plug length and a pressure differential across the cutting plug. The method comprises performing a drilling operation based on the cutting plug friction force.

Abstract: Described herein are topical cream formulations that include a C7-20 alkane, a metal chelating agent, and a buffer.

Abstract: Described herein are formulations including pharmaceutical agents comprising ester and/or lactone ring structures, and methods of using the same. The invention is also directed to a method and ophthalmic pharmaceutical compositions including solution and semisolid dosage forms (i.e. ophthalmic creams, gels, lotions, serums, and/or ointments) of treating a patient with various ocular diseases including presbyopia and dry eyes. The method comprising instructing a patient to apply one strip of the ophthalmic composition to the eyelids that includes pilocarpine or other active pharmaceutical ingredients containing ester and/or lactone ring structures with and without the buffering system.

Abstract: An ophthalmic therapeutic treatment composition includes a topical cream containing a crosslinked acrylic acid polymer, an acrylamide/sodium acryloyldimethyl taurate copolymer, and an effective amount of an active pharmaceutical ingredient (API) dispersed in the topical cream. The ophthalmic therapeutic treatment composition and API are formulated for topical application and treatment of various disorders such as dry eye, presbyopia, intraocular pressure and blepharitis.

Abstract: A three-phase digital power inverter system controlled by a MCU thereof is provided, wherein during a constant current power source for accelerator control in combination with a three-wire potentiometer are inputted to a MCU for qualification and calculation base on a computation algorithm to obtain data, an accelerator line state and a brake line state are detected simultaneously for whether they are working well individually, so as to effectively prevent any electrical failure due to mechanical failure of the accelerator or the brake or open circuit/short circuit of the accelerator line or the brake line that may cause accident due to out of control of the accelerator or brake respectively. These are the potential risk factors of electric motor vehicles while the present invention can substantially eliminate such potential factor and provide a more reliable performance of electric motor vehicles.

Abstract: An ophthalmic topical cream composition includes a topical cream comprising at least one zwitterion; and an active pharmaceutical ingredient (API) dispersed in the topical cream. The ophthalmic topical cream composition and API are formulated for topical application and treatment of various disorders such as dry eye, presbyopia, intraocular pressure and blepharitis.

Abstract: A three-phase digital power inverter system controlled by a MCU thereof is provided, wherein during a constant current power source for accelerator control in combination with a three-wire potentiometer are inputted to a MCU for qualification and calculation base on a computation algorithm to obtain data, an accelerator line state and a brake line state are detected simultaneously for whether they are working well individually, so as to effectively prevent any electrical failure due to mechanical failure of the accelerator or the brake or open circuit/short circuit of the accelerator line or the brake line that may cause accident due to out of control of the accelerator or brake respectively. These are the potential risk factors of electric motor vehicles while the present invention can substantially eliminate such potential factor and provide a more reliable performance of electric motor vehicles.

Abstract: The present disclosure relates to the technical field of medical instrument and provides a passage establishment device for posterior spinal fusion minimally invasive surgery. The device includes: a tube, an interior of the tube includes a through hole penetrating through both axial ends of the tube, and a wall of the tube includes an opening portion. The tube of the passage establishment device of the present disclosure can be inserted between the vertebral bodies and can also be removed from between the vertebral bodies. The through hole of the tube forms a surgical passage for the fusion device to penetrate, which can safely protect human tissues and is convenient for doctors to perform follow-up operations. The tube can be installed quickly, and thus the operation time is shortened. It is easy to disassemble, clean, and disinfect the tube.

Abstract: The present invention relates to a method of and an apparatus for extending the shelf life of an initiated monomer mixture, the method comprising the prevention of premature free radical polymerisation by introducing oxygen or oxygen-containing gas into a container of the initiated monomer mixture and providing mechanical agitation to the container, wherein said introduction and agitation are performed in a temperature and pressure controlled environment.

Abstract: Described herein are formulations including pharmaceutical agents comprising ester and/or lactone ring structures, and methods of using the same. The invention is also directed to a method and ophthalmic pharmaceutical compositions including solution and semisolid dosage forms (i.e. ophthalmic creams, gels, lotions, serums, and/or ointments) of treating a patient with various ocular diseases including presbyopia and dry eyes. The method comprising instructing a patient to apply one strip of the ophthalmic composition to the eyelids that includes pilocarpine or other active pharmaceutical ingredients containing ester and/or lactone ring structures with and without the buffering system.