Abstract: Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.

Abstract: Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.

Abstract: Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, and absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.

Abstract: Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.

Abstract: Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.

Abstract: Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.

Abstract: A method and apparatus of managing remote third party OTN & WDM transceiver equipment using the same fibers used for end user data exchange is described. A network device collects management instructions for the OTN & WDM transceiver equipment, assembles this management information into the overhead of a data frame and transmits on an optical link directly coupled to the network device. The WDM transceiver function converts the optical signal to an electrical one and the OTN function extracts the management instructions from the OTN overhead. A processor associated with the OTN framer function acts on that information. The management instructions includes the instruction to periodically and continuously, load certain performance, alarm or informational data into its OTN overhead and transmit that to a similar transceiver at the remote end of the communications link.

Abstract: An in-band OTDR uses a network's communication protocols to perform OTDR testing on a link. Because the OTDR signal (probe pulse) is handled like a data signal, the time required for OTDR testing is typically about the same as the time required for other global network events, and is not considered an interruption of service to users. A network equipment includes an optical time domain reflectometry (OTDR) transmitter and receiver, each operationally connected to a link to transmit and receive, respectively, an OTDR signal. When an OTDR is to be performed, a network device operationally connected to the link actuates the OTDR transmitter to transmit the OTDR signal on the link during a determined test time based on a communications protocol of the link, during which data signals are not transmitted to the network equipment. A processing system processes the OTDR signal to provide OTDR test results.

Abstract: A method and apparatus of managing remote third party OTN & WDM transceiver equipment using the same fibers used for end user data exchange is described. A network device collects management instructions for the OTN & WDM transceiver equipment, assembles this management information into the overhead of a data frame and transmits on an optical link directly coupled to the network device. The WDM transceiver function converts the optical signal to an electrical one and the OTN function extracts the management instructions from the OTN overhead. A processor associated with the OTN framer function acts on that information. The management instructions includes the instruction to periodically and continuously, load certain performance, alarm or informational data into its OTN overhead and transmit that to a similar transceiver at the remote end of the communications link.

Abstract: A method and apparatus of transmitting a 10 G non-return to zero (NRZ) optical signal over a long length of single mode fiber between a 10 G NRZ optical source and a 10 G digital coherent receiver is described. A device receives a 10 G NRZ optical signal from the 10 G NRZ optical source, where the 10 G NRZ optical signal has an accumulated dispersion that is greater than a dispersion tolerance of an incoherent 10 G NRZ optical receiver. The device further recovers the 10 G NRZ optical signal using the 10 G digital coherent receiver.

Abstract: An in-band OTDR uses a network's communication protocols to perform OTDR testing on a link. Because the OTDR signal (probe pulse) is handled like a data signal, the time required for OTDR testing is typically about the same as the time required for other global network events, and is not considered an interruption of service to users. A network equipment includes an optical time domain reflectometry (OTDR) transmitter and receiver, each operationally connected to a link to transmit and receive, respectively, an OTDR signal. When an OTDR is to be performed, a network device operationally connected to the link actuates the OTDR transmitter to transmit the OTDR signal on the link during a determined test time based on a communications protocol of the link, during which data signals are not transmitted to the network equipment. A processing system processes the OTDR signal to provide OTDR test results.

Abstract: A broad band broadcasting transmission system for sending broad band downstream data and telephone signals from a central office to a number subscriber set top terminal. Each frame of data is marked to indicate the set top terminals it is to be received by. A downstream light fiber is located between the head office and a curbside box. A transmitter transmits the frames along a light fiber to a SAC box. A converter converts the light signals from the light fiber to electrical signals. A distribution line coupled to the curbside box carries the electrical signals to a plurality of drop line twisted pair conductors connected to the distribution line. The drop lines are coupled via a residential units to the set top terminals.