Patents by Inventor Michael Loreto

Michael Loreto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adapter gene
    Patent number: 7507801
    Abstract: The present invention relates to the identification and cloning of a novel gene, MARS (Modulator of Antigen Receptor Signaling), which is a putative tumor suppressor gene. The present invention also relates to the relation of the MARS gene to human cancers and its use in the diagnosis and prognosis of human cancer. The invention also relates to the therapy of human cancers which have a mutation in the MARS gene, or lack the MARS gene, including gene therapy, protein replacement therapy and protein mimetics. Finally, the invention relates to the screening of drugs for cancer therapy.
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: March 24, 2009
    Assignee: The Hospital for Sick Children
    Inventors: Jane McGlade, Michael Loreto
  • Adapter gene
    Publication number: 20040171537
    Abstract: The present invention relates to the identification and cloning of a novel gene, MARS (Modulator of Antigen Receptor Signaling), which is a putative tumor suppressor gene. The present invention also relates to the relation of the MARS gene to human cancers and its use in the diagnosis and prognosis of human cancer. The invention also relates to the therapy of human cancers which have a mutation in the MARS gene, or lack the MARS gene, including gene therapy, protein replacement therapy and protein mimetics. Finally, the invention relates to the screening of drugs for cancer therapy.
    Type: Application
    Filed: November 3, 2003
    Publication date: September 2, 2004
    Inventors: Jane McGlade, Michael Loreto