Abstract: A rotor blade includes an airfoil having an airfoil shape. The airfoil shape has a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in one of Table I, Table II, Table III, Table IV, Table V, Table VI, Table VII, Table VIII, or Table IX. The Cartesian coordinate values of X, Y and Z are non-dimensional values from 0% to 100% convertible to dimensional distances expressed in a unit of distance by multiplying the Cartesian coordinate values of X, Y and Z by a scaling factor of the airfoil in the unit of distance. The X and Y values, when connected by smooth continuing arcs, define airfoil profile sections at each Z value. The airfoil profile sections at Z values are joined smoothly with one another to form a complete airfoil shape.

Abstract: To analyze cybersecurity threats, an analysis module of a processor may receive log data from at least one network node. The analysis module may identify at least one statistical outlier within the log data. The analysis module may determine that the at least one statistical outlier represents a cybersecurity threat by applying at least one machine learning algorithm to the at least one statistical outlier.

Abstract: An electronic exchange platform configured to: receive respective list of approved Buyside participants for each of a plurality of marketmaking orders; receive a respective marketmaking order for a side of trades on the financial instrument from each of the plurality of Sellside participants; peg a price for the received marketmaking orders to a price relative to and multiple ticks behind a best price on the side in an order book; present market information to Buyside participants identifying marketmaking orders for which the Buyside participants are approved; receive a contra order from a Buyside participant that is approved to trade with a subset of the plurality of marketmaking orders, in which the contra order identifies preferred Sellside participants; distribute the contra order; and determine new best bid and offer in response to the distribution; and adjust remaining marketmaking offers to retain peg in response to determining new best bid or offer.

Abstract: Example embodiments are directed to systems and methods for generating and providing elevation-aware hotspots. In example embodiments, a network system detects an initiation of a request for a transportation service at a client device of a user and receives an indication of a location of the client device and corresponding signal strengths associated with the client device. The network system then determines a telematics vector based on the signal strengths associated with the client device. Based on the location of the client device and the telematics vector associated with the client device, the network system identifies one or more top ranked elevation-aware hotspots. A pickup point recommendation is then presented, by the network system on a user interface on the client device of the user, whereby the pickup point recommendation includes the one or more top ranked elevation-aware hotspots.

Abstract: Methods and systems for geothermal energy production wherein multiple horizontal or vertical wells may be used to pass fluids through the Earth from an injector well to a producer well through induced cracks, splits, fractures, conduits, or channels in the rock. Such methods and systems may include controlling tensile-split conduits in a subterranean geothermal formation by providing an injection well, providing a production well, configuring the injection well for injection of a tensile-splitting fluid into a production zone, configuring the production well to produce a heated fluid from the production zone, applying pressure to the production well, creating a plurality of tensile-split conduits, raising or lowering the pressure in the production well, establishing fluid communication between the injection well and the production well, and producing the heated fluid to the surface.

Abstract: Methods and systems for geothermal energy production wherein multiple horizontal or vertical wells may be used to pass fluids through the Earth from an injector well to a producer well through induced cracks, splits, fractures, conduits, or channels in the rock. Such methods and systems may include controlling tensile-split conduits in a subterranean geothermal formation by providing an injection well, providing a production well, configuring the injection well for injection of a tensile-splitting fluid into a production zone, configuring the production well to produce a heated fluid from the production zone, applying pressure to the production well, creating a plurality of tensile-split conduits, raising or lowering the pressure in the production well, establishing fluid communication between the injection well and the production well, and producing the heated fluid to the surface.

Abstract: An aircraft windscreen comprises a plurality of liquid crystal display (LCD) films positioned on or within various portions of the windscreen to define a corresponding plurality of zones. The opacity of the LCD films are individually and separately controllable by control circuitry in communication with user controls to allow a user to darken or lighten portions of the various LCD films to achieve a desired level of gradient tint in the defined zones to block external light, such as sunlight, from the aircraft.

Abstract: A tissue anchor system is provided that includes a first tissue anchor, a second tissue anchor that is separate and distinct from the first tissue anchor, and one or more tethers, which are configured to couple the first tissue anchor to the second tissue anchor. When the first tissue anchor is unconstrained, a head thereof is coaxial with an axis of a shaft thereof, and a tissue-coupling element thereof extends from a distal end of the shaft, is generally orthogonal to the axis, and is shaped such that if the tissue-coupling element were to be projected onto a plane that is perpendicular to the axis, at least 80% of an area of a projection of the tissue-coupling element on the plane would fall within a first angle of 180 degrees in the plane having a vertex at the axis. Other embodiments are also described.

Abstract: Example embodiments are directed to systems and methods for generating and providing elevation-aware hotspots. In example embodiments, a network system detects an initiation of a request for a transportation service at a client device of a user and receives an indication of a location of the client device and corresponding signal strengths associated with the client device. The network system then determines a telematics vector based on the signal strengths associated with the client device. Based on the location of the client device and the telematics vector associated with the client device, the network system identifies one or more top ranked elevation-aware hotspots. A pickup point recommendation is then presented, by the network system on a user interface on the client device of the user, whereby the pickup point recommendation includes the one or more top ranked elevation-aware hotspots.

Abstract: The present disclosure relates to PDE9 inhibitors, pharmaceutical compositions comprising the PDE9 inhibitors, and methods of using the PDE9 pharmaceutical compositions for the treatment of sickle cell disease (SCD).

Abstract: A visual signaling system includes smart signage with a set of three or more lights visible from a single direction. Activation of the lights in a first pattern indicates a hazard and for individuals to move away from the sign. Activation of the lights in a second pattern indicates safety and for individuals to move toward the sign. Activation of the lights in a third pattern indicates a need for caution and for individuals to refrain from approaching the sign. The visual signaling system may include a plurality of smart signs which display different patterns on different signs depending on the location of each sign relative to the hazard, thereby guiding individuals away from the hazard.

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract: 3D metrology techniques are disclosed for determining a changing topography of a substrate processed in an additive manufacturing system. Techniques include fringe scanning, simultaneous fringe projections, interferometry, and x-ray imaging. The techniques can be applied to 3D printing systems to enable rapid topographical measurements of a 3D printer powder bed, or other rapidly moving, nearly continuous surface to be tested. The techniques act in parallel to the system being measured to provide information about system operation and the topography of the product being processed. A tool is provided for achieving higher precision, increasing throughput, and reducing the cost of operation through early detection and diagnosis of operating problems and printing defects. These techniques work well with any powder bed 3D printing system, providing real-time metrology of the powder bed, the most recently printed layer, or both without reducing throughput.

Abstract: The invention relates to methods and products for the identification of a clinically significant immune response in subjects treated with a therapeutic protein. Aspects of the invention relate to methods and compositions for identifying a clinically significant immune response in patients treated with therapeutic amounts of a VLA4 binding antibody (e.g., natalizumab).

Abstract: A method for assisting an operator in operating a machine. The method includes receiving, by a controller, a selection of a task of a plurality of tasks, each task associated with a corresponding movement pattern of the machine; sensing, by a sensor unit, at least one condition of at least one component of the machine associated with the selected task; and determining, by the controller, whether the condition is within a predetermined set of parameters associated with the selected task. In response to determining that the condition is not within the predetermined set of parameters, the method further includes generating, by the controller, an audible or a haptic signal associated with at least one of the condition or the at least one component.

Abstract: Systems and methods for providing security to building occupants include a plurality of smart exit signs positioned at locations in or around a secure area to be monitored. Input devices contained in the smart exit signs are configured to be receptive to sensory activity within the secure area. The system further includes a master controller configured to analyze input signals indicative of the sensory activity detected within the secure area to determine whether a potential security issue exists. Output devices contained in the smart exit signs are configured to receive indication from the master controller when a potential security issue exists. In response to receiving indication from the master controller, the output devices are configured to assist occupants within the secure area to respond to the potential security issue by providing real-time information on optimum exit routes or shelter-in-place locations.

Abstract: According to some embodiments, an assembly configured to be removably secured to an exposed structural component of a vehicle (e.g., a rollbar) comprises a cover assembly configured to secure to the exposed structural component of the vehicle, a hand grip configured to pass through at least a portion of the cover assembly and hand below the cover assembly, wherein the hand grip is configured to be grasped by a user, and at least one tool-receiving member configured to secure to the cover assembly.

Abstract: Systems and methods for providing security to building occupants include a plurality of smart exit signs positioned at locations in or around a secure area to be monitored. Input devices contained in the smart exit signs are configured to be receptive to sensory activity within the secure area. The system further includes a master controller configured to analyze input signals indicative of the sensory activity detected within the secure area to determine whether a potential security issue exists. Output devices contained in the smart exit signs are configured to receive indication from the master controller when a potential security issue exists. In response to receiving indication from the master controller, the output devices are configured to assist occupants within the secure area to respond to the potential security issue by providing real-time information on optimum exit routes or shelter-in-place locations.

Abstract: Disclosed is a natural language processing pipeline that analyzes and processes a corpus of textual data to automatically create a knowledge graph containing the corpus entities such as subjects and object and their relationships such as predicates or verbs. The pipeline is configured as an end-to-end neural Open Schema Construction pipeline having a coreference resolution module, an open information extraction (OIE) module, and an entity canonicalization module. The processed textual data is input to a graph database to create the knowledge graph displayable through a graphical user interface. In operation, the pipeline modules serve to create a single term for all entity mentions in the corpus that reference the same entity through coreference resolution, extract all subject-predicate-object triplets from the coreference resolved corpus through OIE, and then canonicalize the corpus by clustering each entity mention to a canonical form for mapping to the knowledge graph and display.

Abstract: According to some embodiments, an assembly configured to be removably secured to an exposed structural component of a vehicle (e.g., a rollbar) comprises a cover assembly configured to secure to the exposed structural component of the vehicle, a hand grip configured to pass through at least a portion of the cover assembly and hand below the cover assembly, wherein the hand grip is configured to be grasped by a user, and at least one tool-receiving member configured to secure to the cover assembly.