Patents by Inventor Michael M. Haley

Michael M. Haley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220082544
    Abstract: A method for detecting for the presence of H2S or HS? anion in a system, comprising contacting a sample from the system with a compound, or a protonate or salt thereof, having a structure represented by: wherein Y represents an aromatic group or a substituted aromatic group; n is 1 or 2; R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, amido, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, substituted lower alkyl, lower alkyl, substituted aralkyl or aralkyl; R2 is selected from H, acyl, substituted aralkyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 are each independently selected from H, substituted lower alkyl, lower alkyl, substituted aralkyl, aralkyl, substituted aryl or aryl.
    Type: Application
    Filed: November 29, 2021
    Publication date: March 17, 2022
    Applicant: University of Oregon
    Inventors: Michael M. Haley, Michael Pluth, Darren W. Johnson, Sean Fontenot
  • Patent number: 11187690
    Abstract: A method for detecting for the presence of H2S or HS? anion in a system, comprising contacting a sample from the system with a compound, or a protonate or salt thereof, having a structure represented by: wherein Y represents an aromatic group or a substituted aromatic group; n is 1 or 2; R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, amido, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, substituted lower alkyl, lower alkyl, substituted aralkyl or aralkyl; R2 is selected from H, acyl, substituted aralkyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 are each independently selected from H, substituted lower alkyl, lower alkyl, substituted aralkyl, aralkyl, substituted aryl or aryl.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: November 30, 2021
    Assignee: University of Oregon
    Inventors: Michael M. Haley, Michael Pluth, Darren W. Johnson, Sean Fontenot
  • Patent number: 11021447
    Abstract: A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R10 is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: June 1, 2021
    Assignees: University of Oregon, University of Montana
    Inventors: Jessica Lohrman, Darren W. Johnson, Michael M. Haley, Orion B. Berryman, Asia M. Riel, Daniel A. Decato
  • Publication number: 20190345113
    Abstract: A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R10 is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.
    Type: Application
    Filed: May 1, 2019
    Publication date: November 14, 2019
    Applicants: University of Oregon, University of Montana
    Inventors: Jessica Lohrman, Darren W. Johnson, Michael M. Haley, Orion B. Berryman, Asia M. Riel, Daniel A. Decato
  • Patent number: 10060892
    Abstract: A compound, or a protonate or salt thereof, having a formula I of: wherein Y represents an optionally substituted aromatic group; n is 1 or 2; a is 0 to 4; R1 and R2 are each independently H; optionally substituted alkyl; optionally substituted aralkyl; acyl; phosphonyl; —SO2R12; —C(O)R13; —C(O)OR14; —C(O)NR15R16; —C(O)CH2R17; or —C(S)—NR18R19; —S(O)R20; or —SO2NR21R22, wherein R12-R22 are each independently H, optionally substituted alkyl, optionally substituted aralkyl, optionally substituted aryl, or —C(O)R23, wherein R23 is H, optionally substituted alkyl, optionally substituted aralkyl, or optionally substituted aryl; and each R3 is independently optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, amide; amino; or nitro.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: August 28, 2018
    Assignee: University of Oregon
    Inventors: Michelle Watt, Darren W. Johnson, Michael M. Haley
  • Patent number: 9964531
    Abstract: Disclosed herein are host or receptor compounds that bind targets of interest. In one embodiment the compounds bind ions, such as metal ions. A compound, or a protonate or salt thereof, having the formula of: Formula IIa wherein R6 is an aminoalkoxy, alkylamino, nitro or —NH2; n is 1 or 2; each R2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; a is 0 to 4.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: May 8, 2018
    Assignee: University of Oregon
    Inventors: Michael M. Haley, Darren W. Johnson, Jeff Engle, Calden Carroll
  • Patent number: 9876182
    Abstract: Disclosed herein are embodiments of thieno-containing compounds suitable for use in electrical devices and/or electrooptical device. Also disclosed herein are methods of making the disclosed compounds, with particular embodiments of the method concerning a novel dione intermediate that may be used to make particular embodiments of the thieno-containing compounds.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: January 23, 2018
    Assignee: University of Oregon
    Inventors: Michael M. Haley, Aaron G. Fix, Gabriel E. Rudebusch
  • Publication number: 20170350870
    Abstract: A method for detecting for the presence of H2S or HS? anion in a system, comprising contacting a sample from the system with a compound, or a protonate or salt thereof, having a structure represented by: wherein Y represents an aromatic group or a substituted aromatic group; n is 1 or 2; R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, amido, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, substituted lower alkyl, lower alkyl, substituted aralkyl or aralkyl; R2 is selected from H, acyl, substituted aralkyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 are each independently selected from H, substituted lower alkyl, lower alkyl, substituted aralkyl, aralkyl, substituted aryl or aryl.
    Type: Application
    Filed: June 2, 2017
    Publication date: December 7, 2017
    Applicant: University of Oregon
    Inventors: Michael M. Haley, Michael Pluth, Darren W. Johnson, Sean Fontenot
  • Patent number: 9773988
    Abstract: A compound having a structure represented by formula I: wherein each R1 is independently H, alkynyl or substituted alkynyl; each R2 is independently H, alkynyl or substituted alkynyl; each R3 is independently alkyl or halogen; each R4 is independently H, alkyl, or halogen; each R5 is independently H or halogen; n is 0 or 1; and m is 0 or 1, provided that if n is 0 then m is 0, and if n is 1 then m is 1.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: September 26, 2017
    Assignee: University of Oregon
    Inventors: Michael M. Haley, Gabriel Rudebusch
  • Publication number: 20170115262
    Abstract: A compound, or a protonate or salt thereof, having a formula I of: wherein Y represents an optionally substituted aromatic group; n is 1 or 2; a is 0 to 4; R1 and R2 are each independently H; optionally substituted alkyl; optionally substituted aralkyl; acyl; phosphonyl; —S02R12; —C(0)R13; —C(0)OR14; —C(0)NR15R16; —C(0)CH2R17; or —C(S)—NR18R19; —S(0)R20; or —S02NR21R22, wherein R12-R22 are each independently H, optionally substituted alkyl, optionally substituted aralkyl, optionally substituted aryl, or —C(0)R23, wherein R23 is H, optionally substituted alkyl, optionally substituted aralkyl, or optionally substituted aryl; and each R3 is independently optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, amide; amino; or nitro.
    Type: Application
    Filed: December 11, 2014
    Publication date: April 27, 2017
    Inventors: Michelle WATT, Darren W. JOHNSON, Michael M. HALEY
  • Publication number: 20160301021
    Abstract: A compound having a structure represented by formula I: wherein each R1 is independently H, alkynyl or substituted alkynyl; each R2 is independently H, alkynyl or substituted alkynyl; each R3 is independently alkyl or halogen; each R4 is independently H, alkyl, or halogen; each R5 is independently H or halogen; n is 0 or 1; and m is 0 or 1, provided that if n is 0 then m is 0, and if n is 1 then m is 1.
    Type: Application
    Filed: April 6, 2016
    Publication date: October 13, 2016
    Applicant: University of Oregon
    Inventors: Michael M. Haley, Gabriel Rudebusch
  • Publication number: 20160164011
    Abstract: Disclosed herein are embodiments of thieno-containing compounds suitable for use in electrical devices and/or electrooptical device. Also disclosed herein are methods of making the disclosed compounds, with particular embodiments of the method concerning a novel dione intermediate that may be used to make particular embodiments of the thieno-containing compounds.
    Type: Application
    Filed: July 25, 2014
    Publication date: June 9, 2016
    Applicant: University of Oregon
    Inventors: Michael M. Haley, Aaron G. Fix, Gabriel E. Rudebusch
  • Publication number: 20150355153
    Abstract: A compound, or a protonate or salt thereof, having the formula of: wherein R1 is an optionally substituted aromatic group; n is 1 or 2; each R2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; a is 0 to 4; R3 is H or an optionally substituted alkyl; each R4 and R5 is independently selected from H, optionally substituted alkyl, acyl, optionally substituted aralkyl, optionally substituted aryl, or —C(O)R8; and R8 is H, alkyl, aralkyl or aryl.
    Type: Application
    Filed: January 21, 2014
    Publication date: December 10, 2015
    Applicant: University of Oregon
    Inventors: Michael M. Haley, Darren W. Johnson, Jeff Engle, Calden Carroll
  • Patent number: 9099660
    Abstract: Indenofluorenes that include at least two alkynyl-containing substituents.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: August 4, 2015
    Assignee: University of Oregon
    Inventors: Michael M. Haley, Daniel T. Chase, Brad Rose, Aaron G. Fix
  • Patent number: 8921578
    Abstract: A compound having a structure of: wherein X is S, SO, SO2, NR10, O, or Se; R1-R8 are each individually H, amino, alkynyl, substituted alkynyl, halogen, alkyl, aryl, substituted alkyl, substituted aryl, nitro, alkoxy, substituted alkoxy, cyano, thiol, substituted thiol, thioether, hydroxyl, heteroaryl, substituted heteroaryl, cycloalkyl, or substituted cycloalkyl, or R1 and R2 together form an aromatic ring and R5 and R6 together form an aromatic ring; and R10 is selected from H, amino, alkynyl, substituted alkynyl, halogen, alkyl, aryl, substituted alkyl, substituted aryl, nitro, alkoxy, substituted alkoxy, cyano, thiol, substituted thiol, thioether, hydroxyl, heteroaryl, substituted heteroaryl, cycloalkyl, or substituted cycloalkyl.
    Type: Grant
    Filed: December 12, 2012
    Date of Patent: December 30, 2014
    Assignee: State of Oregan Acting by and Through the State Board of Higher Education on Behalf of the University of Oregan
    Inventors: Michael M. Haley, Daniel T. Chase
  • Patent number: 8841460
    Abstract: A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: September 23, 2014
    Assignee: State of Oregon Acting by and Through the State Board of Higher Education on Behalf of the University of Oregon
    Inventors: Darren W. Johnson, Calden Carroll, Michael M. Haley, Jeff Engle
  • Publication number: 20140031559
    Abstract: A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl.
    Type: Application
    Filed: December 14, 2012
    Publication date: January 30, 2014
    Applicant: State of Oregon, acting by and through the State Board of Higher Education on Behalf of University
    Inventors: Darren W. Johnson, Calden Carroll, Michael M. Haley, Jeff Engle
  • Patent number: 8436049
    Abstract: Methods are provided herein for treatment of myotonic dystrophy and other toxic RNA diseases in a subject. In some examples, the method comprises administration of a compound that binds a nucleotide repeat expansion in a ribonucleic acid molecule, thereby treating the disease. In additional examples, the method comprises administration of a compound that disrupts binding of muscleblind-like proteins to an RNA nucleotide repeat expansion. Compounds for use in the disclosed method include pentamidine or heptamidine or derivatives thereof. Representative compounds are described herein.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: May 7, 2013
    Assignee: State of Oregon Acting By and Through the State Board of Higher Education on behalf of the University of Oregon
    Inventors: John Andrew Berglund, M. Bryan Warf, Catherine Matthys, Michael M. Haley, Cameron L. Hilton
  • Publication number: 20130096336
    Abstract: Indenofluorenes that include at least two alkynyl-containing substituents.
    Type: Application
    Filed: June 15, 2011
    Publication date: April 18, 2013
    Inventors: Michael M. Haley, Daniel T. Chase, Brad Rose, Aaron G. Fix
  • Publication number: 20110015396
    Abstract: Disclosed herein is a class of tunable phenylacetylene compounds as well as compositions and methods for their use as host compounds for ligand binding. In certain examples the hosts report binding events by exhibiting altered spectroscopic properties, such as different fluorescent emission spectra.
    Type: Application
    Filed: September 28, 2010
    Publication date: January 20, 2011
    Applicant: The State of Oregon on behalf of the University of Oregon
    Inventors: Michael M. HALEY, Darren W. JOHNSON, Orion B. BERRYMAN, Charles A. JOHNSON, Calden N. STIMPSON