Patents by Inventor Michael M. Haley
Michael M. Haley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220082544Abstract: A method for detecting for the presence of H2S or HS? anion in a system, comprising contacting a sample from the system with a compound, or a protonate or salt thereof, having a structure represented by: wherein Y represents an aromatic group or a substituted aromatic group; n is 1 or 2; R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, amido, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, substituted lower alkyl, lower alkyl, substituted aralkyl or aralkyl; R2 is selected from H, acyl, substituted aralkyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 are each independently selected from H, substituted lower alkyl, lower alkyl, substituted aralkyl, aralkyl, substituted aryl or aryl.Type: ApplicationFiled: November 29, 2021Publication date: March 17, 2022Applicant: University of OregonInventors: Michael M. Haley, Michael Pluth, Darren W. Johnson, Sean Fontenot
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Patent number: 11187690Abstract: A method for detecting for the presence of H2S or HS? anion in a system, comprising contacting a sample from the system with a compound, or a protonate or salt thereof, having a structure represented by: wherein Y represents an aromatic group or a substituted aromatic group; n is 1 or 2; R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, amido, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, substituted lower alkyl, lower alkyl, substituted aralkyl or aralkyl; R2 is selected from H, acyl, substituted aralkyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 are each independently selected from H, substituted lower alkyl, lower alkyl, substituted aralkyl, aralkyl, substituted aryl or aryl.Type: GrantFiled: June 2, 2017Date of Patent: November 30, 2021Assignee: University of OregonInventors: Michael M. Haley, Michael Pluth, Darren W. Johnson, Sean Fontenot
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Patent number: 11021447Abstract: A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R10 is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.Type: GrantFiled: May 1, 2019Date of Patent: June 1, 2021Assignees: University of Oregon, University of MontanaInventors: Jessica Lohrman, Darren W. Johnson, Michael M. Haley, Orion B. Berryman, Asia M. Riel, Daniel A. Decato
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Publication number: 20190345113Abstract: A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R10 is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.Type: ApplicationFiled: May 1, 2019Publication date: November 14, 2019Applicants: University of Oregon, University of MontanaInventors: Jessica Lohrman, Darren W. Johnson, Michael M. Haley, Orion B. Berryman, Asia M. Riel, Daniel A. Decato
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Patent number: 10060892Abstract: A compound, or a protonate or salt thereof, having a formula I of: wherein Y represents an optionally substituted aromatic group; n is 1 or 2; a is 0 to 4; R1 and R2 are each independently H; optionally substituted alkyl; optionally substituted aralkyl; acyl; phosphonyl; —SO2R12; —C(O)R13; —C(O)OR14; —C(O)NR15R16; —C(O)CH2R17; or —C(S)—NR18R19; —S(O)R20; or —SO2NR21R22, wherein R12-R22 are each independently H, optionally substituted alkyl, optionally substituted aralkyl, optionally substituted aryl, or —C(O)R23, wherein R23 is H, optionally substituted alkyl, optionally substituted aralkyl, or optionally substituted aryl; and each R3 is independently optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, amide; amino; or nitro.Type: GrantFiled: December 11, 2014Date of Patent: August 28, 2018Assignee: University of OregonInventors: Michelle Watt, Darren W. Johnson, Michael M. Haley
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Patent number: 9964531Abstract: Disclosed herein are host or receptor compounds that bind targets of interest. In one embodiment the compounds bind ions, such as metal ions. A compound, or a protonate or salt thereof, having the formula of: Formula IIa wherein R6 is an aminoalkoxy, alkylamino, nitro or —NH2; n is 1 or 2; each R2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; a is 0 to 4.Type: GrantFiled: January 21, 2014Date of Patent: May 8, 2018Assignee: University of OregonInventors: Michael M. Haley, Darren W. Johnson, Jeff Engle, Calden Carroll
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Patent number: 9876182Abstract: Disclosed herein are embodiments of thieno-containing compounds suitable for use in electrical devices and/or electrooptical device. Also disclosed herein are methods of making the disclosed compounds, with particular embodiments of the method concerning a novel dione intermediate that may be used to make particular embodiments of the thieno-containing compounds.Type: GrantFiled: July 25, 2014Date of Patent: January 23, 2018Assignee: University of OregonInventors: Michael M. Haley, Aaron G. Fix, Gabriel E. Rudebusch
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Publication number: 20170350870Abstract: A method for detecting for the presence of H2S or HS? anion in a system, comprising contacting a sample from the system with a compound, or a protonate or salt thereof, having a structure represented by: wherein Y represents an aromatic group or a substituted aromatic group; n is 1 or 2; R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, amido, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, substituted lower alkyl, lower alkyl, substituted aralkyl or aralkyl; R2 is selected from H, acyl, substituted aralkyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 are each independently selected from H, substituted lower alkyl, lower alkyl, substituted aralkyl, aralkyl, substituted aryl or aryl.Type: ApplicationFiled: June 2, 2017Publication date: December 7, 2017Applicant: University of OregonInventors: Michael M. Haley, Michael Pluth, Darren W. Johnson, Sean Fontenot
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Patent number: 9773988Abstract: A compound having a structure represented by formula I: wherein each R1 is independently H, alkynyl or substituted alkynyl; each R2 is independently H, alkynyl or substituted alkynyl; each R3 is independently alkyl or halogen; each R4 is independently H, alkyl, or halogen; each R5 is independently H or halogen; n is 0 or 1; and m is 0 or 1, provided that if n is 0 then m is 0, and if n is 1 then m is 1.Type: GrantFiled: April 6, 2016Date of Patent: September 26, 2017Assignee: University of OregonInventors: Michael M. Haley, Gabriel Rudebusch
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Publication number: 20170115262Abstract: A compound, or a protonate or salt thereof, having a formula I of: wherein Y represents an optionally substituted aromatic group; n is 1 or 2; a is 0 to 4; R1 and R2 are each independently H; optionally substituted alkyl; optionally substituted aralkyl; acyl; phosphonyl; —S02R12; —C(0)R13; —C(0)OR14; —C(0)NR15R16; —C(0)CH2R17; or —C(S)—NR18R19; —S(0)R20; or —S02NR21R22, wherein R12-R22 are each independently H, optionally substituted alkyl, optionally substituted aralkyl, optionally substituted aryl, or —C(0)R23, wherein R23 is H, optionally substituted alkyl, optionally substituted aralkyl, or optionally substituted aryl; and each R3 is independently optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, amide; amino; or nitro.Type: ApplicationFiled: December 11, 2014Publication date: April 27, 2017Inventors: Michelle WATT, Darren W. JOHNSON, Michael M. HALEY
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Publication number: 20160301021Abstract: A compound having a structure represented by formula I: wherein each R1 is independently H, alkynyl or substituted alkynyl; each R2 is independently H, alkynyl or substituted alkynyl; each R3 is independently alkyl or halogen; each R4 is independently H, alkyl, or halogen; each R5 is independently H or halogen; n is 0 or 1; and m is 0 or 1, provided that if n is 0 then m is 0, and if n is 1 then m is 1.Type: ApplicationFiled: April 6, 2016Publication date: October 13, 2016Applicant: University of OregonInventors: Michael M. Haley, Gabriel Rudebusch
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Publication number: 20160164011Abstract: Disclosed herein are embodiments of thieno-containing compounds suitable for use in electrical devices and/or electrooptical device. Also disclosed herein are methods of making the disclosed compounds, with particular embodiments of the method concerning a novel dione intermediate that may be used to make particular embodiments of the thieno-containing compounds.Type: ApplicationFiled: July 25, 2014Publication date: June 9, 2016Applicant: University of OregonInventors: Michael M. Haley, Aaron G. Fix, Gabriel E. Rudebusch
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Publication number: 20150355153Abstract: A compound, or a protonate or salt thereof, having the formula of: wherein R1 is an optionally substituted aromatic group; n is 1 or 2; each R2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; a is 0 to 4; R3 is H or an optionally substituted alkyl; each R4 and R5 is independently selected from H, optionally substituted alkyl, acyl, optionally substituted aralkyl, optionally substituted aryl, or —C(O)R8; and R8 is H, alkyl, aralkyl or aryl.Type: ApplicationFiled: January 21, 2014Publication date: December 10, 2015Applicant: University of OregonInventors: Michael M. Haley, Darren W. Johnson, Jeff Engle, Calden Carroll
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Patent number: 9099660Abstract: Indenofluorenes that include at least two alkynyl-containing substituents.Type: GrantFiled: June 15, 2011Date of Patent: August 4, 2015Assignee: University of OregonInventors: Michael M. Haley, Daniel T. Chase, Brad Rose, Aaron G. Fix
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Patent number: 8921578Abstract: A compound having a structure of: wherein X is S, SO, SO2, NR10, O, or Se; R1-R8 are each individually H, amino, alkynyl, substituted alkynyl, halogen, alkyl, aryl, substituted alkyl, substituted aryl, nitro, alkoxy, substituted alkoxy, cyano, thiol, substituted thiol, thioether, hydroxyl, heteroaryl, substituted heteroaryl, cycloalkyl, or substituted cycloalkyl, or R1 and R2 together form an aromatic ring and R5 and R6 together form an aromatic ring; and R10 is selected from H, amino, alkynyl, substituted alkynyl, halogen, alkyl, aryl, substituted alkyl, substituted aryl, nitro, alkoxy, substituted alkoxy, cyano, thiol, substituted thiol, thioether, hydroxyl, heteroaryl, substituted heteroaryl, cycloalkyl, or substituted cycloalkyl.Type: GrantFiled: December 12, 2012Date of Patent: December 30, 2014Assignee: State of Oregan Acting by and Through the State Board of Higher Education on Behalf of the University of OreganInventors: Michael M. Haley, Daniel T. Chase
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Patent number: 8841460Abstract: A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl.Type: GrantFiled: December 14, 2012Date of Patent: September 23, 2014Assignee: State of Oregon Acting by and Through the State Board of Higher Education on Behalf of the University of OregonInventors: Darren W. Johnson, Calden Carroll, Michael M. Haley, Jeff Engle
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Publication number: 20140031559Abstract: A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl.Type: ApplicationFiled: December 14, 2012Publication date: January 30, 2014Applicant: State of Oregon, acting by and through the State Board of Higher Education on Behalf of UniversityInventors: Darren W. Johnson, Calden Carroll, Michael M. Haley, Jeff Engle
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Patent number: 8436049Abstract: Methods are provided herein for treatment of myotonic dystrophy and other toxic RNA diseases in a subject. In some examples, the method comprises administration of a compound that binds a nucleotide repeat expansion in a ribonucleic acid molecule, thereby treating the disease. In additional examples, the method comprises administration of a compound that disrupts binding of muscleblind-like proteins to an RNA nucleotide repeat expansion. Compounds for use in the disclosed method include pentamidine or heptamidine or derivatives thereof. Representative compounds are described herein.Type: GrantFiled: February 20, 2009Date of Patent: May 7, 2013Assignee: State of Oregon Acting By and Through the State Board of Higher Education on behalf of the University of OregonInventors: John Andrew Berglund, M. Bryan Warf, Catherine Matthys, Michael M. Haley, Cameron L. Hilton
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Publication number: 20130096336Abstract: Indenofluorenes that include at least two alkynyl-containing substituents.Type: ApplicationFiled: June 15, 2011Publication date: April 18, 2013Inventors: Michael M. Haley, Daniel T. Chase, Brad Rose, Aaron G. Fix
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Publication number: 20110015396Abstract: Disclosed herein is a class of tunable phenylacetylene compounds as well as compositions and methods for their use as host compounds for ligand binding. In certain examples the hosts report binding events by exhibiting altered spectroscopic properties, such as different fluorescent emission spectra.Type: ApplicationFiled: September 28, 2010Publication date: January 20, 2011Applicant: The State of Oregon on behalf of the University of OregonInventors: Michael M. HALEY, Darren W. JOHNSON, Orion B. BERRYMAN, Charles A. JOHNSON, Calden N. STIMPSON