Abstract: The present invention is directed to compounds of Formulas (I, IIa and IIb): The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, IIa and IIb). Methods of making and using the compounds of Formulas (I, IIa and IIb) are also within the scope of the invention.

Abstract: Disclosed are polymeric foamed compositions, foam padded materials that include such polymeric foamed compositions disposed on a sheet material, and packaging articles (e.g., envelopes) made from such foam padded materials. The polymeric foamed composition on the sheet material has a plurality of foamed structures formed from the foamable composition attached to the sheet material by a layer of the foamable composition, and the plurality foam structures each having a hollow core and a foam exterior shell.

Abstract: The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.

Abstract: Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.

Abstract: A system for collaborative video recording is described. The system may include a reference clock configured to track a reference time. The system may provide, to a plurality of recording devices, a synchronization code for a collaborative video recording session. The system may identify the plurality of recording devices as participants in the collaborative video recording session. The collaborative video recording session may include broadcasting one or more synchronization signals to synchronize the plurality of recording devices to the reference time tracked by the reference clock. The collaborative video recording session may include receiving a plurality of videos from the plurality of recording devices, wherein the plurality of videos comprise timestamps based on synchronization to the reference time. The collaborative video recording session may include generating a shared timeline for the plurality of videos, wherein the shared timeline synchronizes the timestamps between the plurality of videos.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: A handheld computer device is configured to selectively receive a plurality of fluid output values from a paint sprayer and configured to operate in an accessible mode in which the handheld computer device is in a first location where wireless connectivity, via a continuous or near continuous communication path, to at least one of a network server or the paint sprayer is accessible or operate in an inaccessible mode in which the handheld computer device is in a second location out of range of the continuous or near continuous communication path to at least one of the network server or the paint sprayer.

Abstract: An evaporative humidifier including a power unit housing, a blower assembly, a water tank, and a wick. The power unit housing includes an air entrance and an air exit. The blower assembly positioned in the power unit housing, the blower assembly being configured to draw air through the power unit housing when the evaporative humidifier is in an operational state in which humidified air is being supplied to an ambient environment. The water tank configured for storing water, and having no lower water outlet used when in the operational state. The wick positioned in the water tank such that water is drawn into the wick from the water tank, through the wick, and toward an air outlet, and such that when the evaporative humidifier is in the operational state, the blower assembly moves air from the air exit, through the wick, and toward the air outlet.

Abstract: Examples provide methods and apparatus for controlling a DC bias current in an RF amplifier. In one example where the RF amplifier is implemented on an amplifier die, a reference voltage is produced across a reference resistor implemented on the amplifier die, the DC bias current is measured, and a current controller, which is implemented on a controller die that is separate from the amplifier die, operates a feedback loop using the reference voltage to control a level of the DC bias current.

Abstract: An upright reactor body with a perforated interior tube member which extends for the length of the reactor body. A water inlet permits water to be treated into the perforated tube member. A fibrous metal anode surrounds the perforated tube member followed by a surrounding layer of dielectric and then a surrounding metal cathode layer, wherein water from the inlet passes radially through the perforations in the tube member, through the anode, dielectric and cathode members, emerging from the reactor body through an outlet. A DC voltage is imposed on the cathode and anode.

Abstract: The waste water/storm water treatment system includes a plurality of treatment modules, each of which includes upper and lower tank members. Each tank includes an inlet with a spray bar at the upper end thereof, and a drainage member at the lower end thereof. Treated water moves from the drainage member in the upper tank through an inlet at the top of the lower tank. The outlet member of the lower tank is connected to a pump which is controlled by a switch, to move water to the next module in the system or to the drainage system. The tanks have metal-adsorbing inorganic media or agricultural media positioned therein, such as activated rice hulls, corn cobs and the like for adsorbing metals in the storm water/waste water.

Abstract: An upright reactor body with a perforated interior tube member which extends for the length of the reactor body. A water inlet permits water to be treated into the perforated tube member. A fibrous metal anode surrounds the perforated tube member followed by a surrounding layer of dielectric and then a surrounding metal cathode layer, wherein water from the inlet passes radially through the perforations in the tube member, through the anode, dielectric and cathode members, emerging from the reactor body through an outlet. A DC voltage is imposed on the cathode and anode.

Abstract: The waste water/storm water treatment system includes a plurality of treatment modules, each of which includes upper and lower tank members. Each tank includes an inlet with a spray bar at the upper end thereof, and a drainage member at the lower end thereof. Treated water moves from the drainage member in the upper tank through an inlet at the top of the lower tank. The outlet member of the lower tank is connected to a pump which is controlled by a switch, to move water to the next module in the system or to the drainage system. The tanks have metal-adsorbing inorganic media or agricultural media positioned therein, such as activated rice hulls, corn cobs and the like for adsorbing metals in the storm water/waste water.

Abstract: Embodiments of the present invention provides systems and method for detecting. Sensing modules are provided in communication with one or more detectors. In some embodiments, detectors are provided that are sensitive to chemical, biological, or radiological agents. Embodiments of sensing modules include processing capabilities to analyze, perform computations on, and/or run models to predict or interpret data received from one or more detectors. Embodiments of sensing modules form various network configurations with one another and/or with one or more data aggregation devices. Some embodiments of sensing modules include power management functionalities.

Abstract: An apparatus 10 and method for producing a high-energy laser beam 14'". A low-power, good quality, input laser beam 14 is produced by master oscillator 12. The low-power beam 14 is focused at an input focal point 20 and reflected from turning flat 22 to a power amplifier 24 where it is amplified to a moderate power level. It is then transmitted through a polarization beam splitter 28 and its optical path length adjusted by adjustment means 30,32,34,36 prior to being directed to a phase conjugator 44. A quarter-wave plate 40 causes the phase conjugated returning beam 14" to be orthogonally polarized thereby reflecting it from polarization beam splitters 38,28. Beam 14" is then passed through the power amplifier 24 and focused at an output focal point 50 in a vacuum. The resultant high-power output beam 14'" is produced without significant degradation in the beam quality.