Abstract: The embodiments of the present invention relate to a stable liquid vigabatrin pharmaceutical compositions in the liquid form of a solution. Particularly, the stable vigabatrin liquid pharmaceutical composition is manufactured as a ready-to-use industrialized premixture that does not require reconstitution or dilution prior to administration to a patient. The vigabatrin liquid pharmaceutical composition is stable six months or longer at room temperature and has levels of total impurities and Vigabatrin-related compound A that are both not more than 0.04% at, or prior to, six months. In some embodiments, the composition has improved stability and patient compliance. In some embodiments, the compositions may be advantageous for the patients having swallowing difficulties or when the patients are unable to take solid oral dosage forms. In some embodiments, the composition improves compliance with ketogenic diet.

Abstract: The embodiments of the present invention relate to a stable liquid vigabatrin pharmaceutical compositions in the liquid form of a solution. Particularly, the stable vigabatrin liquid pharmaceutical composition is manufactured as a ready-to-use industrialized premixture that does not require reconstitution or dilution prior to administration to a patient. The vigabatrin liquid pharmaceutical composition is stable six months or longer at room temperature and has levels of total impurities and Vigabatrin-related compound A that are both not more than 0.04% at, or prior to, six months. In some embodiments, the composition has improved stability and patient compliance. In some embodiments, the compositions may be advantageous for the patients having swallowing difficulties or when the patients are unable to take solid oral dosage forms. In some embodiments, the composition improves compliance with ketogenic diet.

Abstract: The embodiments of the present invention relate to a stable liquid vigabatrin pharmaceutical compositions in the liquid form of a solution. Particularly, the stable vigabatrin liquid pharmaceutical composition is manufactured as a ready-to-use industrialized premixture that does not require reconstitution or dilution prior to administration to a patient. The vigabatrin liquid pharmaceutical composition is stable six months or longer at room temperature and has levels of total impurities and Vigabatrin-related compound A that are both not more than 0.04% at, or prior to, six months. In some embodiments, the composition has improved stability and patient compliance. In some embodiments, the compositions may be advantageous for the patients having swallowing difficulties or when the patients are unable to take solid oral dosage forms. In some embodiments, the composition improves compliance with ketogenic diet.

Abstract: The embodiments of the present invention relate to a stable liquid vigabatrin pharmaceutical compositions in the liquid form of a solution. Particularly, the stable vigabatrin liquid pharmaceutical composition is manufactured as a ready-to-use industrialized premixture that does not require reconstitution or dilution prior to administration to a patient. The vigabatrin liquid pharmaceutical composition is stable six months or longer at room temperature and has levels of total impurities and Vigabatrin-related compound A that are both not more than 0.04% at, or prior to, six months. In some embodiments, the composition has improved stability and patient compliance. In some embodiments, the compositions may be advantageous for the patients having swallowing difficulties or when the patients are unable to take solid oral dosage forms. In some embodiments, the composition improves compliance with ketogenic diet.

Abstract: The embodiments of the present invention relate to a stable liquid vigabatrin pharmaceutical compositions in the liquid form of a solution. Particularly, the stable vigabatrin liquid pharmaceutical composition is manufactured as a ready-to-use industrialized premixture that does not require reconstitution or dilution prior to administration to a patient. The vigabatrin liquid pharmaceutical composition is stable six months or longer at room temperature and has levels of total impurities and Vigabatrin-related compound A that are both not more than 0.04% at, or prior to, six months. In some embodiments, the composition has improved stability and patient compliance. In some embodiments, the compositions may be advantageous for the patients having swallowing difficulties or when the patients are unable to take solid oral dosage forms. In some embodiments, the composition improves compliance with ketogenic diet.

Abstract: In one embodiment, a method for determining query return referent data for concept types in a conceptual graph includes generating a conceptual graph for a document query, the conceptual graph comprising a plurality of graph terms, identifying one of more of the plurality of graph terms needing referent data, identifying conceptually similar terms for each of the graph terms, for the graph terms needing referents, identifying referent data by searching for instances where conceptually similar terms for graph terms needing referent data are associated by conceptually similar terms for the linking concept term, and associating identified referent data with the graph terms needing referent data.

Abstract: In one embodiment, a method for determining concept attributes for a concept term includes receiving a concept term and determining one or more word senses for the concept term. A word sense is selected from the one or more word senses, and, based on the selected word sense, one or more conceptually similar terms for the concept term is determined. The method also includes determining that at least one of the one or more conceptually similar terms is a concept attribute for the concept term and generating a mapping to associate the concept attribute with the concept term. The mapping is stored in an onomasticon.

Abstract: In one embodiment, a method for determining concept attributes for a concept term includes receiving a concept term and determining one or more word senses for the concept term. A word sense is selected from the one or more word senses, and, based on the selected word sense, one or more conceptually similar terms for the concept term is determined. The method also includes determining that at least one of the one or more conceptually similar terms is a concept attribute for the concept term and generating a mapping to associate the concept attribute with the concept term. The mapping is stored in an onomasticon.

Abstract: In one embodiment, a method for expanding concept attributes for a concept term includes receiving an attribute term for expansion and determining one or more word senses for the attribute term. A word sense is selected from the one or more word senses. One or more conceptually similar terms is selected for the attribute term based on the word sense and it is determined that that at least one of the one or more conceptually similar terms is an additional attribute. A first mapping associating the additional attribute with the attribute term is generated, and a second mapping associating the additional attribute with the concept term is generated. The mappings are stored in an onomasticon.

Abstract: In one embodiment, a method for determining referents for concept types in a conceptual graph includes generating a conceptual graph for a search query, the conceptual graph comprising a plurality of graph terms, identifying at least one graph term needing referents, identifying referents for each graph term needing referents by searching for instances where conceptually similar terms for graph terms needing referents are associated by conceptually similar terms for the linking concept term; and associating identified referents with the graph terms needing referents.

Abstract: In one embodiment, a method for determining query return referent data for concept types in a conceptual graph includes generating a conceptual graph for a document query, the conceptual graph comprising a plurality of graph terms, identifying one of more of the plurality of graph terms needing referent data, identifying conceptually similar terms for each of the graph terms, for the graph terms needing referents, identifying referent data by searching for instances where conceptually similar terms for graph terms needing referent data are associated by conceptually similar terms for the linking concept term, and associating identified referent data with the graph terms needing referent data.

Abstract: A turbocharger is provided with a tubular insert that carries engine coolant to an area adjacent the bearing supporting the end of the shaft upon which the turbine wheel is attached to provide cooling so that the temperature of the bearing does not increase to an unacceptable level.

Abstract: A label holder for a product information label is suspended from a wire rod forming part of a wire basket, wire shelf, or the like containing the product, the label holder having elongate tabs along the upper margin which loop around the rod and attach to the body of the holder. The tabs have adhesive inner surfaces which are pressed into engagement with the rod so as to stabilize the label holder against swaying when traversed by a bar code reader.