Patents by Inventor Michael Madani

Michael Madani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250136758
    Abstract: Methods and hydrogels for preventing or reducing cellular adhesion and protein adsorption to a tissue (e.g. cardiac tissue) are disclosed. The hydrogels generally include at least three component polymers, a first polymer including an aminooxy group, a second polymer including a reactive oxo group, that are cross-linked by oxime bonds and a third polymer including a catechol group, that causes better retention on the cardiac tissue. The hydrogels are suitable for binding to and coating a tissue or cell. The hydrogels operate to reduce cellular adhesions and protein adsorption to the tissue or cell.
    Type: Application
    Filed: June 27, 2024
    Publication date: May 1, 2025
    Inventors: Karen Christman, Masaki Fujita, Michael Madani
  • Publication number: 20230027018
    Abstract: Methods and hydrogels for preventing or reducing cellular adhesion and protein adsorption to a tissue (e.g. cardiac tissue) are disclosed. The hydrogels generally include at least three component polymers, a first polymer including an aminooxy group, a second polymer including a reactive oxo group, that are cross-linked by oxime bonds and a third polymer including a catechol group, that causes better retention on the cardiac tissue. The hydrogels are suitable for binding to and coating a tissue or cell. The hydrogels operate to reduce cellular adhesions and protein adsorption to the tissue or cell.
    Type: Application
    Filed: August 5, 2022
    Publication date: January 26, 2023
    Inventors: Karen Christman, Masaki Fujita, Michael Madani
  • Patent number: 11440992
    Abstract: Methods and hydrogels for preventing or reducing cellular adhesion and protein adsorption to a tissue (e.g. cardiac tissue) are disclosed. The hydrogels generally include at least three component polymers, a first polymer including an aminooxy group, a second polymer including a reactive oxo group, that are cross-linked by oxime bonds and a third polymer including a catechol group, that causes better retention on the cardiac tissue. The hydrogels are suitable for binding to and coating a tissue or cell. The hydrogels operate to reduce cellular adhesions and protein adsorption to the tissue or cell.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: September 13, 2022
    Assignee: The Regents of the University of California
    Inventors: Karen Christman, Masaki Fujita, Michael Madani
  • Patent number: 10611880
    Abstract: Methods and hydrogels for preventing or reducing cellular adhesion and protein adsorption to a tissue (e.g. cardiac tissue) are disclosed. The hydrogels generally include at least two component polymers, a first polymer including an aminooxy group and a second polymer including a reactive oxo group, that are cross-linked by oxime bonds. The hydrogels are suitable for binding to and coating a tissue or cell. The hydrogels operate to reduce cellular adhesions and protein adsorption to the tissue or cell.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: April 7, 2020
    Assignee: The Regents of the University of California
    Inventors: Karen Christman, Gregory Grover, Michael Madani, Masaki Fujita
  • Publication number: 20200102422
    Abstract: Methods and hydrogels for preventing or reducing cellular adhesion and protein adsorption to a tissue (e.g. cardiac tissue) are disclosed. The hydrogels generally include at least three component polymers, a first polymer including an aminooxy group, a second polymer including a reactive oxo group, that are cross-linked by oxime bonds and a third polymer including a catechol group, that causes better retention on the cardiac tissue. The hydrogels are suitable for binding to and coating a tissue or cell. The hydrogels operate to reduce cellular adhesions and protein adsorption to the tissue or cell.
    Type: Application
    Filed: March 27, 2018
    Publication date: April 2, 2020
    Inventors: Karen Christman, Masaki Fujita, Michael Madani
  • Publication number: 20170362380
    Abstract: Methods and hydrogels for preventing or reducing cellular adhesion and protein adsorption to a tissue (e.g. cardiac tissue) are disclosed. The hydrogels generally include at least two component polymers, a first polymer including an aminooxy group and a second polymer including a reactive oxo group, that are cross-linked by oxime bonds. The hydrogels are suitable for binding to and coating a tissue or cell. The hydrogels operate to reduce cellular adhesions and protein adsorption to the tissue or cell.
    Type: Application
    Filed: December 9, 2015
    Publication date: December 21, 2017
    Inventors: Karen Christman, Gregory Grover, Michael Madani, Masaki Fujita