Patents by Inventor Michael Malicdem

Michael Malicdem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multiplex compositions and methods for quantification of human nuclear DNA and human male DNA and detection of PCR inhibitors
    Patent number: 9481909
    Abstract: The invention relates to a method for simultaneous quantification of human nuclear DNA and human male DNA in a biological sample while also detecting the presence of PCR inhibitors in a single reaction. The multiplex quantification method also provides a ratio of human nuclear and male DNA present in a biological sample. Such sample characterization is useful for achieving efficient and accurate results in downstream molecular techniques such as genotyping.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: November 1, 2016
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Jaiprakash Shewale, Manohar Furtado, Pius Brzoska, Maura Barbisin, Rixun Fang, Michael Malicdem, Cristin O'Shea
  • Human single nucleotide polymorphisms
    Patent number: 9260757
    Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci which can cause allelic dropout. Also disclosed are kits useful in human identification.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: February 16, 2016
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Julio Mulero, Michael Malicdem, Robert Lagace
  • MULTIPLEX COMPOSITIONS AND METHODS FOR QUANTIFICATION OF HUMAN NUCLEAR DNA AND HUMAN MALE DNA AND DETECTION OF PCR INHIBITORS
    Publication number: 20150361493
    Abstract: The invention relates to a method for simultaneous quantification of human nuclear DNA and human male DNA in a biological sample while also detecting the presence of PCR inhibitors in a single reaction. The multiplex quantification method also provides a ratio of human nuclear and male DNA present in a biological sample. Such sample characterization is useful for achieving efficient and accurate results in downstream molecular techniques such as genotyping.
    Type: Application
    Filed: June 19, 2015
    Publication date: December 17, 2015
    Inventors: Jaiprakash SHEWALE, Manohar Furtado, Pius Brzoska, Maura Barbisin, Rixun Fang, Michael Malicdem, Cristin O'Shea
  • NOVEL HUMAN SINGLE NUCLEOTIDE POLYMORPHISMS
    Publication number: 20150322522
    Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci which can cause allelic dropout. Also disclosed are kits useful in human identification.
    Type: Application
    Filed: May 11, 2015
    Publication date: November 12, 2015
    Inventors: Julio MULERO, Michael Malicdem, Robert Lagace
  • Human single nucleotide polymorphisms within CODIS loci D13S317, TH01, vWA, D12S391, and D6S1043
    Patent number: 9029088
    Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci D13S317, TH01, vWA, D12S391 and D6S1043, which can cause allelic dropout. Also disclosed are kits useful in human identification.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: May 12, 2015
    Assignee: Life Technologies Corporation
    Inventors: Julio Mulero, Michael Malicdem, Robert Lagace
  • Multiplex compositions and methods for quantification of human nuclear DNA and human male DNA and detection of PCR inhibitors
    Patent number: 8445657
    Abstract: The invention relates to a method for simultaneous quantification of human nuclear DNA and human male DNA in a biological sample while also detecting the presence of PCR inhibitors in a single reaction. The multiplex quantification method also provides a ratio of human nuclear and male DNA present in a biological sample. Such sample characterization is useful for achieving efficient and accurate results in downstream molecular techniques such as genotyping.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: May 21, 2013
    Assignee: Applied Biosystems, LLC
    Inventors: Jaiprakash Shewale, Manohar Furtado, Pius Brzoska, Maura Barbisin, Rixun Fang, Michael Malicdem, Cristin O'Shea
  • MULTIPLEX COMPOSITIONS AND METHODS FOR QUANTIFICATION OF HUMAN NUCLEAR DNA AND HUMAN MALE DNA AND DETECTION OF PCR INHIBITORS
    Publication number: 20120015370
    Abstract: The invention relates to a method for simultaneous quantification of human nuclear DNA and human male DNA in a biological sample while also detecting the presence of PCR inhibitors in a single reaction. The multiplex quantification method also provides a ratio of human nuclear and male DNA present in a biological sample. Such sample characterization is useful for achieving efficient and accurate results in downstream molecular techniques such as genotyping.
    Type: Application
    Filed: August 26, 2011
    Publication date: January 19, 2012
    Applicant: Applied Biosystems, LLC
    Inventors: Jaiprakash G. SHEWALE, Manohar Furtado, Pius Brzoska, Maura Barbisin, Rixun Fang, Michael Malicdem, Cristin O'Shea
  • Multiplex compositions and methods for quantification of human nuclear DNA and human male DNA and detection of PCR inhibitors
    Patent number: 8012691
    Abstract: The invention relates to a method for simultaneous quantification of human nuclear DNA and human male DNA in a biological sample while also detecting the presence of PCR inhibitors in a single reaction. The multiplex quantification method also provides a ratio of human nuclear and male DNA present in a biological sample. Such sample characterization is useful for achieving efficient and accurate results in downstream molecular techniques such as genotyping.
    Type: Grant
    Filed: February 20, 2008
    Date of Patent: September 6, 2011
    Assignee: Applied Biosystems, LLC
    Inventors: Jaiprakash G. Shewale, Manohar Furtado, Pius Brzoska, Maura Barbisin, Rixun Fang, Michael Malicdem, Cristin O'Shea
  • NOVEL HUMAN SINGLE NUCLEOTIDE POLYMORPHISMS
    Publication number: 20110183857
    Abstract: Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci which can cause allelic dropout. Also disclosed are kits useful in human identification.
    Type: Application
    Filed: October 15, 2010
    Publication date: July 28, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Julio Mulero, Michael Malicdem, Robert Lagace
  • Multiplex compositions and methods for quantification of human nuclear DNA and human male DNA and detection of PCR inhibitors
    Publication number: 20080268448
    Abstract: The invention relates to a method for simultaneous quantification of human nuclear DNA and human male DNA in a biological sample while also detecting the presence of PCR inhibitors in a single reaction. The multiplex quantification method also provides a ratio of human nuclear and male DNA present in a biological sample. Such sample characterization is useful for achieving efficient and accurate results in downstream molecular techniques such as genotyping.
    Type: Application
    Filed: February 20, 2008
    Publication date: October 30, 2008
    Applicant: Applera Corporation
    Inventors: Jaiprakash G. Shewale, Manohar Furtado, Pius Brzoska, Maura Barbisin, Rixun Fang, Michael Malicdem, Cristin O'Shea