Patents by Inventor Michael Mandler

Michael Mandler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1H-BENZO[D]IMIDAZOLE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS
    Publication number: 20230295122
    Abstract: The present invention relates to 1H-benzo[d]imidazole derivatives of formula (I) or a salt thereof. The present compounds are inhibitors of TLR9 and useful in treating preventing, or slowing fibrotic diseases, such as e.g. liver fibrosis, renal fibrosis, biliary fibrosis or pancreatic fibrosis, non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), chronic kidney disease, diabetic kidney disease, primary sclerosing cholangitis (PSC) or primary biliary cirrhosis (PBC), or idiopathic pulmonary fibrosis (IPF).
    Type: Application
    Filed: August 18, 2021
    Publication date: September 21, 2023
    Inventors: David S. Yoon, Alicia Regueiro-Ren, Michael Mandler, Shoshana L. Posy, Chunjian Liu
  • Carton including detachable coupon
    Patent number: 4872555
    Abstract: A carton formed from a carton blank in which an end closure comprises at least three flaps hingedly connected to the carton front, back, and side walls, including the major flaps opposite one another and a minor flap having printing or other marking thereon for detachment as a coupon or for the commercial use. The minor flap carrying the printing or marking extends a substantial distance into the end closure opening.
    Type: Grant
    Filed: October 15, 1987
    Date of Patent: October 10, 1989
    Assignee: Sunshine Biscuits, Inc.
    Inventors: William S. Shadrach III, Michael Mandler, Ihor D. Moch, Bernard Zitomer, John L. Stewart II