Abstract: Disclosed herein are cable sealing devices having features for enhancing effective sealing, volume compensation, seal pressurization, cable size range-taking, cable installation and insert installation. Also disclosed herein is an enclosure including at least one cable sealing device.

Abstract: The present disclosure relates to methods, devices and systems for co-axially aligning first and second optical fibers to provide an optical coupling between the first and second optical fibers. A fiber engagement element is used to force the first and second optical fibers into an alignment groove.

Abstract: The present invention relates to single domain antibodies (SDAs) that are capable of binding to tetanus neurotoxin. The invention further relates to polypeptide constructs comprising such an SDA as well as an SDA that is capable of binding to a serum protein, preferably to serum albumin or immunoglobulin. The invention also relates to nucleic acids encoding such SDAs or polypeptide constructs, to pharmaceutical compositions comprising such SDAs or polypeptide constructs, the medical use thereof and to their use in the treatment of tetanus.

Abstract: The present invention relates to single domain antibodies (SDAs) that are capable of binding to tetanus neurotoxin. The invention further relates to polypeptide constructs comprising such an SDA as well as an SDA that is capable of binding to a serum protein, preferably to serum albumin or immunoglobulin. The invention also relates to nucleic acids encoding such SDAs or polypeptide constructs, to pharmaceutical compositions comprising such SDAs or polypeptide constructs, the medical use thereof and to their use in the treatment of tetanus.

Abstract: A method of encryption key provisioning that includes providing, by a quantum computing safe method, a shared secret data to a device and to a security service; using the provided shared secret data to provide a root key; and using the root key for a sequence of stages, wherein each stage includes an operation which converts a start key into a different generated key, and the same stages are carried out in parallel at the device and at the security service; wherein the root key is used as the start key for a first stage, and a generated key produced by each stage, except for the final stage, is used as a start key for a next stage of the sequence; and wherein the generated keys produced by the last stage of the sequence at the device and at the security service are symmetric keys.

Abstract: The present disclosure relates to a ferrule-less multi-fiber connector having features adapted to compensate or adjust for angular misalignment that may occur when the multi-fiber connector is optically connected with a corresponding ferrule-less multi-fiber connector. In one example, the features for adjusting for angular misalignment are integrated in a multi-fiber holder that mounts within a connector body of the fiber optic connector.

Abstract: Systems, methods, and associated components for robotic manipulation of physical objects. The physical objects include three-dimensional gripping features configured to be detected by an optics system and gripped by an end-effector of a robotic arm with sufficient gripping force to move the physical objects against the force of gravity. Sets of the physical objects can have different sizes and shapes and, in some examples, include identically constructed three-dimensional gripping features.

Abstract: Disclosed herein are cable sealing devices having features for enhancing effective sealing, volume compensation, seal pressurization, cable size range-taking, cable installation and insert installation. Also disclosed herein is an enclosure including at least one cable sealing device.

Abstract: The present invention relates to single domain antibodies (SDAs) that are capable of binding to tetanus neurotoxin. The invention further relates to polypeptide constructs comprising such an SDA as well as an SDA that is capable of binding to a serum protein, preferably to serum albumin or immunoglobulin. The invention also relates to nucleic acids encoding such SDAs or polypeptide constructs, to pharmaceutical compositions comprising such SDAs or polypeptide constructs, the medical use thereof and to their use in the treatment of tetanus.

Abstract: Aspects and techniques of the present disclosure relate to a cable sealing structure comprising a cable sealing body including a gel and methods of making anisotropic behavior in cable sealing structures made with a dry silicone gel. In one aspect, various three-dimensional printing techniques are used to make a cable sealing structure that includes a gel. The cable sealing body has a construction that elastically deforms to apply an elastic spring load to the gel. The cable sealing body has a construction with anisotropic deformation characteristics that allows the cable sealing body to be less deformable in one direction than in others. The cable sealing structure can be utilized to seal fiber optic cables more uniformly while limiting the potential of leakage.

Abstract: A device having an armature including a main wall; a rotary part intended to be mechanically coupled to a control shaft of an electrical switching unit; a bar integral with the rotary part and able to rotate between a first position and a second position and extending through a slot in the main wall; a position sensor having a movable contact pushed into a retracted position by the bar when the bar is in the first position; a stabilizing device having a resilient strip extending along the slot in order to exert a retaining force on the bar when it is in the first position.

Abstract: The present disclosure relates to connector ports with shutters configured to inhibit dust intrusion by including peripheral regions that oppose undercut portions of the connector port when the shutter is closed. The present disclosure also relates to fiber optic connectors having latching configurations with double latches for retaining the fiber optic connectors in connector ports. The present disclosure also relates to a fiber optic connector including a plurality of stacked fiber carrier modules. The present disclosure also relates to a fiber optic connector including a connector body and a rear connector piece that is secured to the connector body by a snap-fit connection. The rear connector piece can be configured for attachment to a fiber optic cable. The rear connector piece can be secured to the connector body by a snap-fit connection. The rear connector piece can have a snap-fit interface compatible with a number of different styles or types of connector bodies to promote manufacturing efficiency.

Abstract: A computer system is associated with a number of computers including at least one central processing unit (CPU). Managing of parallel processing on the computer system may comprise determining a scheduling limit to restrict a number of worker threads available for executing tasks on the computer system. The managing may further comprise executing a plurality of tasks on the computer system. An availability of a CPU associated with the computer system is determined based on whether a load of the CPU exceeds a first threshold. When the CPU is determined to be unavailable, the scheduling limit is reduced. A further task is scheduled for execution on one of the CPUs according to the reduced scheduling limit. The worker threads available to execute tasks on the computer system may be limited, such that the quantity of worker threads available for executing tasks does not exceed the scheduling limit.

Abstract: Systems, methods, and associated components for robotic manipulation of physical objects. The physical objects include three-dimensional gripping features configured to be detected by an optics system and gripped by an end-effector of a robotic arm with sufficient gripping force to move the physical objects against the force of gravity. Sets of the physical objects can have different sizes and shapes and, in some examples, include identically constructed three-dimensional gripping features.

Abstract: An air circuit breaker includes two separable electrical contacts connected to electric current input and output terminals; and a chamber for quenching an electric arc, including a stack of splitter plates that are spaced apart from one another, and lateral walls placed on either side of the stack and including a thermosetting-resin impregnated polyamide woven and being devoid of glass fibres. The quenching chamber furthermore includes protective elements made of crosslinked polyamide, the elements being placed in junction zones between the lateral walls and holding plates, the protective elements covering corners of the splitter plates, which corners are adjacent to the lateral walls, so as to separate these corners of the splitter plates from the electrical contacts.

Abstract: A computer system is associated with a number of computers including at least one central processing unit (CPU). Managing of parallel processing on the computer system may comprise determining a scheduling limit to restrict a number of worker threads available for executing tasks on the computer system. The managing may further comprise executing a plurality of tasks on the computer system. An availability of a CPU associated with the computer system is determined based on whether a load of the CPU exceeds a first threshold. When the CPU is determined to be unavailable, the scheduling limit is reduced. A further task is scheduled for execution on one of the CPUs according to the reduced scheduling limit. The worker threads available to execute tasks on the computer system may be limited, such that the quantity of worker threads available for executing tasks does not exceed the scheduling limit.

Abstract: A pluggable electrical device for switching an electrical current includes a static frame including a rigid backplate fastened to the frame; connection terminals able to be connected to an electrical installation; and a removable portion including a device for switching an electrical current. The backplate is made of a thermosetting polymer and includes reinforcing beams integrated into the backplate and extending in a vertical direction.

Abstract: The present disclosure is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention provides polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS-derived drug, the polypeptides encoded by such polynucleotides, expression vectors comprising the polynucleotides, host cells comprising the polynucleotides or expression vectors, and kits comprising a host cell. Also provided is a method for the production of ET-743, the NRPS-derived drug.

Abstract: Provided herein are compositions of compounds of formula (I), methods of inhibiting a bacterial infection by contacting a cell with a composition comprising a compound of formula (I), and methods of isolating compounds of formula (I) from an extract of Streptomyces tempisquensis.

Abstract: The present disclosure is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention provides polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS-derived drug, the polypeptides encoded by such polynucleotides, expression vectors comprising the polynucleotides, host cells comprising the polynucleotides or expression vectors, and kits comprising a host cell. Also provided is a method for the production of ET-743, the NRPS-derived drug.