Patents by Inventor Michael Maria Helmut Schumacher

Michael Maria Helmut Schumacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neuroprotection and myelin repair using Nestorone®
    Patent number: 10052335
    Abstract: Methods for treating neurodegeneration and/or myelination in patients are disclosed comprising treating the patient with a progestin compound which exerts binding to progesterone receptors and elicits progesterone-receptor-induced biological responses without interacting with the androgen receptor and without inducing androgen or glucocorticoid biological responses at a dosage sufficient to prevent or reduce neurodegeneration. The progestin compound preferably comprises 16-methylene-17?-acetoxy-19-norpregn-4-ene-3,20-dione, and the methods include combining the progestin compound with an estrogen compound to provide both contraception and treatment for myelin repair and neurodegeneration.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: August 21, 2018
    Assignee: The Population Council, Inc.
    Inventors: Regine Sitruk-Ware, Michael Maria Helmut Schumacher, Roberta Brinton, Martine El-Etr, Abdelmouman Ghoumari, Rachida Guennoun
  • Neuroprotection and myelin repair using nestorone®
    Patent number: 9446051
    Abstract: Methods for treating neurodegeneration and/or myelination in patients are disclosed comprising treating the patient with a progestin compound which exerts binding to progesterone receptors and elicits progesterone-receptor-induced biological responses without interacting with the androgen receptor and without inducing androgen or glucocorticoid biological responses at a dosage sufficient to prevent or reduce neurodegeneration. The progestin compound preferably comprises 16-methylene-17?-acetoxy-19-norpregn-4-ene-3,20-dione, and the methods include combining the progestin compound with an estrogen compound to provide both contraception and treatment for myelin repair and neurodegeneration, and include effects on stroke and TBI.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: September 20, 2016
    Assignee: The Population Council, Inc.
    Inventors: Regine Sitruk-Ware, Michael Maria Helmut Schumacher, Roberta Brinton, Martine El-Etr, Abdelmouman Ghoumari, Rachida Guennoun
  • Myelin regeneration with androgens
    Patent number: 9364488
    Abstract: Methods for effective remyelination in patients are disclosed comprising treating the patient with an androgen receptor ligand which exerts binding to androgen receptors and elicits androgen-receptor-induced biological responses at a dosage sufficient to induce remyelination. The androgen compound preferably comprises MENT in an androgen targeting both androgen and estrogen receptors, and the methods include combining the androgen compound with a progestin compound in order to provide both contraception in men and treatment for neurodegeneration.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: June 14, 2016
    Assignee: The Population Council, Inc.
    Inventors: Regine Sitruk-Ware, Michael Maria Helmut Schumacher, Abdelmouman Ghoumari, Said Ghandour, Rashad Hussain, Bartosz Bielecki
  • MYELIN REGENERATION WITH ANDROGENS
    Publication number: 20140011791
    Abstract: Methods for effective remyelination in patients are disclosed comprising treating the patient with an androgen receptor ligand which exerts binding to androgen receptors and elicits androgen-receptor-induced biological responses at a dosage sufficient to induce remyelination. The androgen compound preferably comprises MENT in an androgen targeting both androgen and estrogen receptors, and the methods include combining the androgen compound with a progestin compound in order to provide both contraception in men and treatment for neurodegeneration.
    Type: Application
    Filed: March 22, 2012
    Publication date: January 9, 2014
    Applicant: THE POPULATION COUNCIL, INC.
    Inventors: Regine Sitruk-Ware, Michael Maria Helmut Schumacher, Abdelmouman Ghoumari, Said Ghandour, Rashad Hussain, Bartosz Bielecki
  • NEUROPROTECTION AND MYELIN REPAIR USING NESTORONE®
    Publication number: 20120231052
    Abstract: Methods for treating neurodegeneration and/or myelination in patients are disclosed comprising treating the patient with a progestin compound which exerts binding to progesterone receptors and elicits progesterone-receptor-induced biological responses without interacting with the androgen receptor and without inducing androgen or glucocorticoid biological responses at a dosage sufficient to prevent or reduce neurodegeneration. The progestin compound preferably comprises 16-methylene-17?-acetoxy-19-norpregn-4-ene-3,20-dione, and the methods include combining the progestin compound with an estrogen compound to provide both contraception and treatment for myelin repair and neurodegeneration.
    Type: Application
    Filed: October 19, 2010
    Publication date: September 13, 2012
    Applicant: THE POPULATION COUNCIL, INC.
    Inventors: Regine Sitruk-Ware, Michael Maria Helmut Schumacher, Roberta Brinton, Martine El-Etr, Abdelmouman Ghoumari, Rachida Guennoun