Patents by Inventor Michael Mark Morgen

Michael Mark Morgen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS TO ACHIEVE RAPID DISSOLUTION OF DRUG FROM SPRAY-DRIED DISPERSIONS IN CAPSULES
    Publication number: 20180161269
    Abstract: Disclosed are dosage forms comprising a capsule and a fill material, comprising (a) a fill material comprising a dispersion of an active agent and a polymer, the dispersion being granulated, (b) an osmogen, and (c) a glidant. In one embodiment, the dispersion comprises 10 wt % to 90 wt % of the fill material, the osmogen comprises from 5 wt % to 40 wt % of the fill material, and the glidant comprises at least 0.1 wt % of the fill material.
    Type: Application
    Filed: May 26, 2016
    Publication date: June 14, 2018
    Applicant: Capsugel Belgium NV
    Inventors: Michael Mark Morgen, Aaron Keith Goodwin
  • NANOPARTICLE FORMULATIONS OF LOW-WATER SOLUBILITY ACTIVES
    Publication number: 20170209375
    Abstract: Disclosed are compositions including nanoparticles comprising a poorly aqueous soluble polymer, an ionizable active agent, and a counterion having an opposite charge as the ionizable active agent, as well as methods of making and using the compositions.
    Type: Application
    Filed: July 15, 2015
    Publication date: July 27, 2017
    Applicant: Bend Research, Inc.
    Inventors: Warren Kenyon Miller, Michael Mark Morgen
  • N-(4-PHENYL)-N'-(3-FLUOROPHENYL)UREA DOCUSATE
    Publication number: 20170197980
    Abstract: Docusate salts of N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N?-(3-fluorophenyl)urea are suitable pharmaceutical ingredients for pharmaceutical compositions useful in the treatment of disease, for example, cancer.
    Type: Application
    Filed: June 25, 2015
    Publication date: July 13, 2017
    Inventors: Lloyd S. Dias, Rodney James Ketner, Jonathan M. Miller, Warren Kenyon Miller, Michael Mark Morgen, Brice George Murri, David Thomas Vodak
  • Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
    Patent number: 8974827
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric amphiphilic non-ionizable block copolymer.
    Type: Grant
    Filed: May 26, 2008
    Date of Patent: March 10, 2015
    Assignee: Bend Research, Inc.
    Inventors: Corey Jay Bloom, Marshall David Crew, Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
    Patent number: 8703204
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a poorly aqueous soluble non-ionizable polymer.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: April 22, 2014
    Assignee: Bend Research, Inc.
    Inventors: Corey Jay Bloom, Marshall David Crew, Daniel Tod Smithey, Warren Kenyon Miller, Michael Mark Morgen
  • Nanoparticles comprising a drug, ethylcellulose, and a bile salt
    Patent number: 8309129
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, ethylcellulose, and a bile salt.
    Type: Grant
    Filed: April 21, 2008
    Date of Patent: November 13, 2012
    Assignee: Bend Research, Inc.
    Inventors: Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • NANOPARTICLES COMPRISING A NON-IONIZABLE CELLULOSIC POLYMER AND AN AMPHIPHILIC NON-IONIZABLE BLOCK COPOLYMER
    Publication number: 20100323014
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric amphiphilic non-ionizable block copolymer.
    Type: Application
    Filed: May 26, 2008
    Publication date: December 23, 2010
    Inventors: Corey Jay Bloom, Marshall David Crew, Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • NANOPARTICLES COMPRISING IONIZABLE, POORLY WATER SOLUBLE CELLULOSIC POLYMERS
    Publication number: 20100215747
    Abstract: A pharmaceutical composition comprises nanoparticles comprising ionizable, poorly water soluble cellulosic polymers.
    Type: Application
    Filed: June 30, 2008
    Publication date: August 26, 2010
    Inventors: Corey Jay Bloom, Marshall David Crew, Dwayne T. Friesen, Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • NANOPARTICLES COMPRISING A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR AND ANON-IONIZABLE POLYMER
    Publication number: 20100129447
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a poorly aqueous soluble non-ionizable polymer.
    Type: Application
    Filed: April 23, 2008
    Publication date: May 27, 2010
    Inventors: Corey Jay Bloom, Marshall David Crew, Daniel Tod Smithey, Warren Kenyon Miller, Michael Mark Morgen
  • NANOPARTICLES COMPRISING NON-CRYSTALLINE DRUG
    Publication number: 20100119612
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a core of non-crystalline drug and surface stabilizers consisting of a phospholipid and a bile salt.
    Type: Application
    Filed: April 7, 2008
    Publication date: May 13, 2010
    Inventors: Dwayne Thomas Friesen, Daniel Tod Smithey, Michael Mark Morgen, Ralph Tadday
  • NANOPARTICLES COMPRISING A DRUG,ETHYCELLULOSE,AND A BILE SALT
    Publication number: 20100119603
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, ethylcellulose, and a bile salt.
    Type: Application
    Filed: April 21, 2008
    Publication date: May 13, 2010
    Inventors: warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • PHARMACEUTICAL COMPOSITIONS COMPRISING NANOPARTICLES COMPRISING ENTERIC POLYMERS CASEIN
    Publication number: 20100062073
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug and an enteric polymer, and casein.
    Type: Application
    Filed: November 16, 2007
    Publication date: March 11, 2010
    Inventors: Ronald Arthur Beyerinck, Corey Jay Bloom, Marshall David Crew, Dwayne Thomas Friesen, Michael Mark Morgen, Daniel Tod Smithey