Patents by Inventor Michael Markl

Michael Markl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260131552
    Abstract: A rotary press includes upper and lower press punches, a die plate defining a plurality of cavities, a filling apparatus that dispenses powder material into the plurality cavities, and a pressing apparatus that presses the powder material in the plurality of cavities into pellets. A scraping apparatus scrapes pellets ejected from the die plate into a first pellet discharge and a sorting apparatus sorts the pellets into a second pellet discharge. The sorting apparatus includes a sorting drive including an electric motor with a magnet driven by a stator and a transmission element, and a sorting element driven by the sorting drive between a sorting position and a rest position. In the sorting position, the sorting element guides pellets into the second pellet discharge. The magnet translates a drive movement, via the transmission element, into a drive movement of the sorting element with a higher drive speed.
    Type: Application
    Filed: November 12, 2025
    Publication date: May 14, 2026
    Applicant: Fette Compacting GmbH
    Inventors: Thomas Pannewitz, Michael Markl
  • Patent number: 12579644
    Abstract: Esophageal bolus transport and esophageal mechanics are quantified from medical imaging data, such as dynamic magnetic resonance imaging (“MRI”) data, computed tomography (“CT”) data, or the like. A machine learning model is used to process geometric or other spatiotemporal parameters of a bolus imaged with medical imaging in order to estimate quantitative parameters of the bolus and/or esophagus, such as cross-sectional area, fluid velocity, and fluid pressure. From these values, other parameters can be computed, such as esophageal stiffness and active relaxation.
    Type: Grant
    Filed: August 9, 2023
    Date of Patent: March 17, 2026
    Assignee: Northwestern University
    Inventors: Sourav Halder, Ethan M. Johnson, Jun Yamasaki, Peter J. Kahrilas, Michael Markl, John Erik Pandolfino, Neelesh A. Patankar
  • Publication number: 20260043443
    Abstract: A radially actuated drum brake for a commercial vehicle has a brake drum, an anchor housing with bearing receptacles for brake linings, at least two brake linings, which are mounted in respective bearing receptacles in an accommodation space of the brake drum, each of the brake linings having a friction lining carrier, a friction lining arranged thereon, and a pressure piece, which is arranged on an underside of the lining carrier, the underside facing away from the friction lining, and protrudes radially in the direction of the rotational axis of the brake drum through an opening in the relevant bearing receptacle. An application device is arranged on a cylinder sleeve of the anchor housing and has at least one pressing part with which the brake linings can be pressed against an inner lateral face of the brake drum in an application direction radial to the rotational axis of the brake drum.
    Type: Application
    Filed: August 7, 2025
    Publication date: February 12, 2026
    Inventors: Frederic SCHROEPF, Johann Iraschko, Ralf Weber, Rudolf Fischer, Abdelaziz Rguichi, Michael Markl
  • Publication number: 20250325236
    Abstract: A method for non-invasive assessment of vascular 4D hemodynamics includes receiving standard anatomic imaging data at a local network or cloud-based analysis platform and identifying a vessel of interest from the received anatomic imaging data. The method also includes deriving hemodynamic features from the vessel of interest from the received anatomic imaging data using deep learning by inputting the received anatomic imaging data into a deep learning network. The method further includes calculating 4D hemodynamic parameters and generating output data based on the hemodynamic features derived from the vessel of interest.
    Type: Application
    Filed: May 5, 2023
    Publication date: October 23, 2025
    Inventors: Bradley Allen, Michael Markl, Ulas Bagci
  • Publication number: 20250040894
    Abstract: A system and method for predicting cardiovascular function is presented. The method includes accessing physiological measurement data and patient data from a patient. The method also includes accessing a neural network trained to predict cardiovascular function data using the physiological measurement data and patient data.
    Type: Application
    Filed: August 1, 2024
    Publication date: February 6, 2025
    Inventors: Ethan Johnson, Mahmoud Ebrahimkhani, Michael Markl
  • Patent number: 12023165
    Abstract: Described here are systems and methods for generating cardiac vibrational energy spectral (“VIBES”) heat maps from physical vibration data and cardiac cycle timing data measured from a subject. Quick screening for heart valve, cardiovascular, and/or cardiothoracic abnormalities can be provided based on an analysis and/or classification of the generated VIBES heat maps.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: July 2, 2024
    Assignee: Northwestern University
    Inventors: Ethan M. I. Johnson, Michael Markl
  • Publication number: 20240062370
    Abstract: Esophageal bolus transport and esophageal mechanics are quantified from medical imaging data, such as dynamic magnetic resonance imaging (“MRI”) data, computed tomography (“CT”) data, or the like. A machine learning model is used to process geometric or other spatiotemporal parameters of a bolus imaged with medical imaging in order to estimate quantitative parameters of the bolus and/or esophagus, such as cross-sectional area, fluid velocity, and fluid pressure. From these values, other parameters can be computed, such as esophageal stiffness and active relaxation.
    Type: Application
    Filed: August 9, 2023
    Publication date: February 22, 2024
    Inventors: Sourav Halder, Ethan M. Johnson, Jun Yamasaki, Peter J. Kahrilas, Michael Markl, John Erik Pandolfino, Neelesh A. Patankar
  • Patent number: 11398303
    Abstract: Described here are systems and methods for generating and analyzing co-expression signature data from scalar or multi-dimensional data fields contained in or otherwise derived from imaging data acquired with a medical imaging system. A similarity metric, such as an angular similarity metric, is computed between the data field components contained in pairs of voxels in the data field data. The data fields can be scalar fields, vector fields, tensor fields, or other higher-dimensional data fields. A probability distribution of these similarity metrics can be generated and used as co-expression signature data that indicate pairwise disparities in the data field data.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: July 26, 2022
    Assignee: Northwestern University
    Inventors: Mohammed S. M. Elbaz, Michael Markl
  • Publication number: 20220151500
    Abstract: Described here are systems and methods for generating quantitative flow mapping from medical flow data (e.g., medical images, patient-specific computational flow models, particle image velocimetry data, in vitro flow phantom) over a virtual volume representative of a catheter or other medical device. As such, quantitative flow mapping is provided with reduced computational burdens. Quantitative flow maps can also be generated and displayed in a manner that is similar to catheter-based or other medical device-based mapping, without requiring an interventional procedure to place the catheter or medical device.
    Type: Application
    Filed: November 12, 2019
    Publication date: May 19, 2022
    Inventors: Mohammed S.M. Elbaz, Michael Markl
  • Publication number: 20220125367
    Abstract: Described here are systems and methods for generating cardiac vibrational energy spectral (“VIBES”) heat maps from physical vibration data and cardiac cycle timing data measured from a subject. Quick screening for heart valve, cardiovascular, and/or cardiothoracic abnormalities can be provided based on an analysis and/or classification of the generated VIBES heat maps.
    Type: Application
    Filed: October 25, 2021
    Publication date: April 28, 2022
    Inventors: Ethan M. I. Johnson, Michael Markl
  • Publication number: 20210065875
    Abstract: Described here are systems and methods for generating and analyzing co-expression signature data from scalar or multi-dimensional data fields contained in or otherwise derived from imaging data acquired with a medical imaging system. A similarity metric, such as an angular similarity metric, is computed between the data field components contained in pairs of voxels in the data field data. The data fields can be scalar fields, vector fields, tensor fields, or other higher-dimensional data fields. A probability distribution of these similarity metrics can be generated and used as co-expression signature data that indicate pairwise disparities in the data field data.
    Type: Application
    Filed: August 27, 2020
    Publication date: March 4, 2021
    Inventors: Mohammed S.M. Elbaz, Michael Markl
  • Patent number: 10241180
    Abstract: Described here are systems and methods for producing an image that depicts blood flow stasis using magnetic resonance imaging (MRI), Doppler echocardiography, or other medical instruments for measuring flow velocities in a human body. A time series of three-dimensional (3D) image volumes is provided, where this time series of 3D image volumes contains flow velocity information at voxel locations in a 3D volume in a subject. One or more regions-of-interest are then segmented from the 3D image volumes. For each voxel in the regions-of-interest, velocity magnitudes are calculated. Using the velocity magnitudes, a flow stasis volume is produced by computing a relative stasis value for each voxel location in the corresponding region-of-interest. This flow stasis volume can be provided as a 3D flow stasis image, or a flow stasis map can be produced by projecting the flow stasis volume onto a two-dimensional (2D) plane.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: March 26, 2019
    Assignee: Northwestern University
    Inventors: Michael Markl, Jeffrey J. Goldberger
  • Patent number: 10109050
    Abstract: A computer-implemented method for performing spatiotemporal background phase correction for phase contrast velocity encoded magnetic resonance imaging includes performing a phase contrast magnetic resonance imaging scan of a region of interest within a patient to yield a complex image and calculating a plurality of filter cut-off frequencies based on physiological limits associated with the patient. A spatiotemporal filter is created based on the plurality of filter cut-off frequencies. This spatiotemporal filter is applied to the complex image to yield a low-pass filtered complex image. Then, complex division is performed using the complex image and the low-pass filtered complex image to yield a corrected image.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: October 23, 2018
    Assignees: Siemens Healthcare GmbH, Northwestern University
    Inventors: Bruce S. Spottiswoode, Michael Markl, Ning Jin
  • Publication number: 20180031662
    Abstract: Described here are systems and methods for producing an image that depicts blood flow stasis using magnetic resonance imaging (MRI), Doppler echocardiography, or other medical instruments for measuring flow velocities in a human body. A time series of three-dimensional (3D) image volumes is provided, where this time series of 3D image volumes contains flow velocity information at voxel locations in a 3D volume in a subject. One or more regions-of-interest are then segmented from the 3D image volumes. For each voxel in the regions-of-interest, velocity magnitudes are calculated. Using the velocity magnitudes, a flow stasis volume is produced by computing a relative stasis value for each voxel location in the corresponding region-of-interest. This flow stasis volume can be provided as a 3D flow stasis image, or a flow stasis map can be produced by projecting the flow stasis volume onto a two-dimensional (2D) plane.
    Type: Application
    Filed: January 29, 2016
    Publication date: February 1, 2018
    Inventors: Michael Markl, Jeffrey J. Goldberger
  • Publication number: 20170352151
    Abstract: A computer-implemented method for performing spatiotemporal background phase correction for phase contrast velocity encoded magnetic resonance imaging includes performing a phase contrast magnetic resonance imaging scan of a region of interest within a patient to yield a complex image and calculating a plurality of filter cut-off frequencies based on physiological limits associated with the patient. A spatiotemporal filter is created based on the plurality of filter cut-off frequencies. This spatiotemporal filter is applied to the complex image to yield a low-pass filtered complex image. Then, complex division is performed using the complex image and the low-pass filtered complex image to yield a corrected image.
    Type: Application
    Filed: June 1, 2016
    Publication date: December 7, 2017
    Inventors: Bruce S. Spottiswoode, Michael Markl, Ning Jin
  • Patent number: 9638778
    Abstract: A method for operating a Magnetic Resonance (MR) imaging system includes generating radio frequency (RF) excitation pulses in patient anatomy to provide subsequent acquisition of associated RF echo data and generating slice select magnetic field gradients for phase encoding and readout RF data acquisition in the patient anatomy. The method also includes acquiring a plurality of slices of an image within a plurality of cycles, each of the plurality of slices being acquired within each of the plurality of cycles and causing, by a control processor, a RF signal generator and a gradient generator to change an order that each of the plurality of slices is acquired between consecutive cycles of the plurality of cycles.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: May 2, 2017
    Assignees: Northwestern University, Siemens Healthcare GmbH
    Inventors: Michael Markl, Bruce S Spottiswoode
  • Patent number: 9498140
    Abstract: Disclosed herein is a framework for facilitating waveform parameter estimation. In accordance with one aspect, time-based waveforms are generated based on analysis planes positioned along a centerline of the vessel. A surface may be fitted to upslope regions of the waveforms to determine one or more waveform parameters based on intersection of the surface with the upslope regions.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: November 22, 2016
    Inventors: Patrick Magrath, Bruce S. Spottiswoode, Aurélien Stalder, Mehmet Akif Gulsun, Michael Markl
  • Publication number: 20150324977
    Abstract: Disclosed herein is a framework for facilitating waveform parameter estimation. In accordance with one aspect, time-based waveforms are generated based on analysis planes positioned along a centerline of the vessel. A surface may be fitted to upslope regions of the waveforms to determine one or more waveform parameters based on intersection of the surface with the upslope regions.
    Type: Application
    Filed: May 5, 2015
    Publication date: November 12, 2015
    Inventors: Patrick Magrath, Bruce S. Spottiswoode, Aurélien Stalder, Mehmet Akif Gulsun, Michael Markl
  • Publication number: 20140159720
    Abstract: A method for operating a Magnetic Resonance (MR) imaging system includes generating radio frequency (RF) excitation pulses in patient anatomy to provide subsequent acquisition of associated RF echo data and generating slice select magnetic field gradients for phase encoding and readout RF data acquisition in the patient anatomy. The method also includes acquiring a plurality of slices of an image within a plurality of cycles, each of the plurality of slices being acquired within each of the plurality of cycles and causing, by a control processor, a RF signal generator and a gradient generator to change an order that each of the plurality of slices is acquired between consecutive cycles of the plurality of cycles.
    Type: Application
    Filed: December 5, 2013
    Publication date: June 12, 2014
    Inventors: Michael Markl, Bruce S. Spottiswoode
  • Patent number: 7951215
    Abstract: A filtering plant for removing dusts from gases, with a plurality of filter units, which are parallel connected to a line for crude gas and the outlets thereof are parallel connected to a line for purified gas, wherein an extraction blowing engine is connected to the line for purified gas, further with an apparatus for cleaning the filter units, which has a lower collecting space for the filter cake with a discharge opening with flap on the lower end of the collecting space, characterized in that the dust discharge openings of all the filter units except one are connected to a common collecting main and the collecting main is connected to the crude gas region of the one filter unit.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: May 31, 2011
    Assignee: Fette GmbH
    Inventors: Harald Römer, Detlef Nuppenau, Eugen Krüger, Dieter Schmidt, Michael Markl, Bernd Granzow, Jens Mannshard