Patents by Inventor Michael Marquant

Michael Marquant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11215577
    Abstract: A test system for analyzing a sample of a bodily fluid is provided and comprises: at least one test strip comprising at least one capillary channel comprising an inlet opening configured to receive the sample; a vent opening configured to provide an air vent to the capillary channel; and at least one zone consisting of a detection zone and a reagent zone; at least one measuring device configured for interacting with the test strip, the measuring device comprising at least one sealing element for hermetically sealing the vent opening from an ambient atmosphere; and at least one suction device adapted to provide an underpressure to the vent opening; wherein the measuring device further comprises at least one valve or is connectable to the valve, wherein the valve is configured to vent the vent opening of the test strip when the measuring device interacts with the test strip.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: January 4, 2022
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Uwe Goebbert, EloĆ­sa Lopez-Calle, Michael Marquant, Christine Nortmeyer, Katja Reiter, Reiner Stein
  • Publication number: 20210349049
    Abstract: A method for determining a concentration of at least one analyte in bodily fluid, comprising: a signal generation step, wherein an excitation voltage signal is generated by a signal generator, wherein the excitation voltage signal comprises a poly frequent alternating current (AC) voltage and a direct current (DC) voltage profile, wherein the poly frequent AC voltage comprises at least two frequencies; a signal application step, wherein the excitation voltage signal is applied to at least two measurement electrodes; a measurement step, wherein a response is measured by using the measurement electrodes; an evaluation step, wherein an AC current response for each frequency and a DC current response are evaluated from the response; a determination step, wherein the concentration of the analyte is determined from the DC current response and from one or both of the phase and impedance information by using at least one predetermined relationship.
    Type: Application
    Filed: July 23, 2021
    Publication date: November 11, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Marquant, Samuel Evgin, Melanie Klein
  • Patent number: 11125712
    Abstract: A method for determining a concentration of at least one analyte in bodily fluid, comprising: a signal generation step, wherein an excitation voltage signal is generated by a signal generator, wherein the excitation voltage signal comprises a poly frequent alternating current (AC) voltage and a direct current (DC) voltage profile, wherein the poly frequent AC voltage comprises at least two frequencies; a signal application step, wherein the excitation voltage signal is applied to at least two measurement electrodes; a measurement step, wherein a response is measured by using the measurement electrodes; an evaluation step, wherein an AC current response for each frequency and a DC current response are evaluated from the response; a determination step, wherein the concentration of the analyte is determined from the DC current response and from one or both of the phase and impedance information by using at least one predetermined relationship.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: September 21, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Michael Marquant, Samuel Evgin, Melanie Klein
  • Patent number: 11099149
    Abstract: A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: August 24, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Klaus Andreas Bauer-Espindola, Michael Marquant, Christine Nortmeyer, Reiner Stein
  • Publication number: 20210080420
    Abstract: A test element for electrochemically detecting at least one analyte in a bodily fluid is disclosed. The test element comprises at least one first electrode and at least one second electrode. The first electrode is designed as a working electrode and the second electrode is designed as a counter electrode. The test element comprises at least one capillary capable of receiving a sample of the body fluid. The first electrode and the second electrode are arranged on opposing sides of the capillary. The first electrode and the second electrode are arranged such that during a capillary filling the first electrode and the second electrode are wetted simultaneously and at an equal rate.
    Type: Application
    Filed: November 30, 2020
    Publication date: March 18, 2021
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Klaus Andreas Bauer-Espindola, Michael Marquant, Christine Nortmeyer, Reiner Stein
  • Publication number: 20200292483
    Abstract: A method for determining a concentration of at least one analyte in bodily fluid, comprising: a signal generation step, wherein an excitation voltage signal is generated by a signal generator, wherein the excitation voltage signal comprises a poly frequent alternating current (AC) voltage and a direct current (DC) voltage profile, wherein the poly frequent AC voltage comprises at least two frequencies; a signal application step, wherein the excitation voltage signal is applied to at least two measurement electrodes; a measurement step, wherein a response is measured by using the measurement electrodes; an evaluation step, wherein an AC current response for each frequency and a DC current response are evaluated from the response; a determination step, wherein the concentration of the analyte is determined from the DC current response and from one or both of the phase and impedance information by using at least one predetermined relationship.
    Type: Application
    Filed: June 14, 2019
    Publication date: September 17, 2020
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Marquant, Samuel Evgin, Melanie Klein
  • Patent number: 10716504
    Abstract: A medical system is disclosed, which can be useable in particular for monitoring and/or controlling at least one bodily function of a user. The medical system comprises a control device and at least one medical user element embodied separately from the control device. The medical user element and the control device are designed to exchange data wirelessly. The medical system is designed to enable an automatic assignment step, wherein an exchange of personal data between the medical user element and the control device is enabled by the automatic assignment step. The medical system is furthermore designed to automatically initiate the automatic assignment step by means of an assignment coupling between the medical user element and the control device. The medical system is furthermore designed to enable a separation of the assignment coupling for medical operation of the medical system after the assignment step.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: July 21, 2020
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Nicole Bernini, Harvey B. Buck, Jr., Andreas Eberhart, Sybille Froech, Otto Gaa, Michael Marquant, Juergen Rasch-Menges, Bernd Roesicke, Joerg Scherer
  • Publication number: 20200225184
    Abstract: A method for determining an information on an equivalent series resistance is disclosed and comprises: generating at least one excitation voltage signal and applying the excitation voltage to at least two measurement electrodes; measuring a response signal; determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and determining the information on the equivalent series resistance from the ohmic signal portion.
    Type: Application
    Filed: March 25, 2020
    Publication date: July 16, 2020
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Lambertson, Klaus Bauer-Espindola, Samuel Evgin, Carina Horn, Michael Marquant
  • Publication number: 20200140914
    Abstract: A method of detecting at least one analyte in a test sample is provided comprising a) contacting the test sample (i) to an active chemistry matrix changing at least one electrochemical property dependent on an enzymatic activity active in the presence of the analyte, the active chemistry matrix contacting a first electrode; and (ii) to an inactive chemistry matrix, the inactive chemistry matrix contacting a second electrode, b) closing an electrical circuit including the first electrode, the second electrode, and the active chemistry matrix and inactive chemistry matrix, followed by determining a first value of the at least one electrochemical property, c) inverting electrical polarity of the electrical circuit of b), followed by determining a second value of the at least one electrochemical property, and d) detecting the at least one analyte based on the first value and on the second value.
    Type: Application
    Filed: January 7, 2020
    Publication date: May 7, 2020
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Marquant, Michael Reinhardt
  • Patent number: 10620148
    Abstract: A method and test element for electrochemically detecting at least one analyte in a sample are provided, wherein the method comprises: a) providing at least one test element comprising at least one first electrode contacting a test chemistry and at least one second electrode, wherein a surface of the second electrode consists of silver metal; b) contacting both the first and second electrodes with the sample comprising chloride ions; c) applying a first voltage between the first electrode as a cathode and the second electrode as an anode with a voltage sufficient for forming a layer of silver chloride at the surface of the second electrode; d) applying a second voltage between the first electrode as the anode and the second electrode as the cathode; and e) determining an electrical signal between the first and the second electrodes, whereby the analyte in the sample comprising the chloride ions is detected.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: April 14, 2020
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Michael Marquant
  • Patent number: 10590458
    Abstract: A method of detecting at least one analyte in a test sample is provided comprising a) contacting the test sample (i) to an active chemistry matrix changing at least one electrochemical property dependent on an enzymatic activity active in the presence of the analyte, the active chemistry matrix contacting a first electrode; and (ii) to an inactive chemistry matrix, the inactive chemistry matrix contacting a second electrode, b) closing an electrical circuit including the first electrode, the second electrode, and the active chemistry matrix and inactive chemistry matrix, followed by determining a first value of the at least one electrochemical property, c) inverting electrical polarity of the electrical circuit of b), followed by determining a second value of the at least one electrochemical property, and d) detecting the at least one analyte based on the first value and on the second value.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: March 17, 2020
    Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Michael Marquant, Michael Reinhardt
  • Publication number: 20190310221
    Abstract: A method for determining a concentration of at least one analyte in bodily fluid, comprising: a signal generation step, wherein an excitation voltage signal is generated by a signal generator, wherein the excitation voltage signal comprises a poly frequent alternating current (AC) voltage and a direct current (DC) voltage profile, wherein the poly frequent AC voltage comprises at least two frequencies; a signal application step, wherein the excitation voltage signal is applied to at least two measurement electrodes; a measurement step, wherein a response is measured by using the measurement electrodes; an evaluation step, wherein an AC current response for each frequency and a DC current response are evaluated from the response; a determination step, wherein the concentration of the analyte is determined from the DC current response and from one or both of the phase and impedance information by using at least one predetermined relationship.
    Type: Application
    Filed: June 14, 2019
    Publication date: October 10, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Marquant, Samuel Evgin, Melanie Klein
  • Patent number: 10359390
    Abstract: A method is disclosed for determining analyte concentration that includes applying a first electrical potential excitation pulse to a body fluid sample in an analyte sensor, and a first current response of the body fluid sample to the first pulse is measured. A second excitation pulse is applied to the body fluid sample in the analyte sensor, and a second current response of the body fluid sample to the second pulse is measured. An analyte level in the body fluid sample is determined by compensating for sources of error based on the first current response to the first pulse.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: July 23, 2019
    Assignee: ROCHE DIABETES CARE, INC.
    Inventors: David W. Burke, Michael Marquant, Nigel A. Surridge
  • Publication number: 20190079045
    Abstract: A test system for analyzing a sample of a bodily fluid is provided and comprises: at least one test strip comprising at least one capillary channel comprising an inlet opening configured to receive the sample; a vent opening configured to provide an air vent to the capillary channel; and at least one zone consisting of a detection zone and a reagent zone; at least one measuring device configured for interacting with the test strip, the measuring device comprising at least one sealing element for hermetically sealing the vent opening from an ambient atmosphere; and at least one suction device adapted to provide an underpressure to the vent opening; wherein the measuring device further comprises at least one valve or is connectable to the valve, wherein the valve is configured to vent the vent opening of the test strip when the measuring device interacts with the test strip.
    Type: Application
    Filed: November 9, 2018
    Publication date: March 14, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Uwe Goebbert, Eloisa Lopez-Calle, Michael Marquant, Christine Nortmeyer, Katja Reiter, Reiner Stein
  • Patent number: 10180420
    Abstract: A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: January 15, 2019
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Klaus Andreas Bauer-Espindola, Carina Horn, Michael Marquant, Christine Nortmeyer, Volker Unkrig
  • Patent number: 10060877
    Abstract: The invention relates to an electrochemical sensor for the determination of a concentration of at least one analyte in a medium, in particular a body tissue and/or a body fluid, to an apparatus that includes the electrochemical sensor, and to a use of the electrochemical sensor, and finally to a method for producing it. The electrochemical sensor has an isolation element and at least two electrodes. The at least two electrodes comprise at least one working electrode and at least one further electrode, in particular at least one counter electrode and/or at least one reference electrode. The at least two electrodes run parallel to one another and form an electrochemical measuring cell of the electrochemical sensor.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: August 28, 2018
    Assignee: ROCHE DIABETES CARE, INC.
    Inventors: Gregor Bainczyk, Michael Marquant
  • Publication number: 20180100826
    Abstract: A method and test element for electrochemically detecting at least one analyte in a sample are provided, wherein the method comprises: a) providing at least one test element comprising at least one first electrode contacting a test chemistry and at least one second electrode, wherein a surface of the second electrode consists of silver metal; b) contacting both the first and second electrodes with the sample comprising chloride ions; c) applying a first voltage between the first electrode as a cathode and the second electrode as an anode with a voltage sufficient for forming a layer of silver chloride at the surface of the second electrode; d) applying a second voltage between the first electrode as the anode and the second electrode as the cathode; and e) determining an electrical signal between the first and the second electrodes, whereby the analyte in the sample comprising the chloride ions is detected.
    Type: Application
    Filed: December 4, 2017
    Publication date: April 12, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventor: Michael Marquant
  • Publication number: 20170357766
    Abstract: A medical system is disclosed, which can be useable in particular for monitoring and/or controlling at least one bodily function of a user. The medical system comprises a control device and at least one medical user element embodied separately from the control device. The medical user element and the control device are designed to exchange data wirelessly. The medical system is designed to enable an automatic assignment step, wherein an exchange of personal data between the medical user element and the control device is enabled by the automatic assignment step. The medical system is furthermore designed to automatically initiate the automatic assignment step by means of an assignment coupling between the medical user element and the control device. The medical system is furthermore designed to enable a separation of the assignment coupling for medical operation of the medical system after the assignment step.
    Type: Application
    Filed: August 28, 2017
    Publication date: December 14, 2017
    Inventors: Nicole BERNINI, Harvey B. BUCK, JR., Andreas EBERHART, Sybille FROECH, Otto GAA, Michael MARQUANT, Juergen RASCH-MENGES, Bernd ROESICKE, Joerg SCHERER
  • Patent number: 9840729
    Abstract: Azo compounds are disclosed that do not form azoxy dimers and that do not have any reactive nitroso groups. Also disclosed are use of the azo compounds as mediators in optical and electrochemical diagnostic methods, as well as detection reagents, kits and test elements that include such azo compounds and that can be used in the diagnostic methods.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: December 12, 2017
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Stacy H. Duvall, Peter Gebauer, Dieter Heindl, Carina Horn, Peter Kratzsch, Michael Marquant, Thomas Meier
  • Patent number: 9773093
    Abstract: A medical system is disclosed, which can be useable in particular for monitoring and/or controlling at least one bodily function of a user. The medical system comprises a control device and at least one medical user element embodied separately from the control device. The medical user element and the control device are designed to exchange data wirelessly. The medical system is designed to enable an automatic assignment step, wherein an exchange of personal data between the medical user element and the control device is enabled by the automatic assignment step. The medical system is furthermore designed to automatically initiate the automatic assignment step by means of an assignment coupling between the medical user element and the control device. The medical system is furthermore designed to enable a separation of the assignment coupling for medical operation of the medical system after the assignment step.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: September 26, 2017
    Assignee: ROCHE DIABETES CARE, INC.
    Inventors: Nicole Bernini, Harvey B. Buck, Jr., Andreas Eberhart, Sybille Froech, Otto Gaa, Michael Marquant, Juergen Rasch-Menges, Bernd Roesicke, Joerg Scherer