Abstract: Polymorphs of chemical compounds that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. Also provided herein are processes for preparing compounds, polymorphs thereof, and pharmaceutical compositions thereof.

Abstract: A transport assembly with a box portion including a box surface, a box front, a box back, and a pair of box sides, wherein the front, back, and sides each extend from the box surface, wherein a gap extends between the front and each of the sides; and a drawer portion including a drawer surface, a drawer front, and a pair of drawer sides, wherein the drawer front and drawer sides each extend from the drawer surface, the drawer surface and drawer sides define an open back portion that faces the drawer front, a gap extends between the drawer front and each of the drawer sides, and the box portion and drawer portion can be arranged such that an inner surface of the drawer front faces an outer surface of the box front and an inner surface of each box side faces an outer surface of a corresponding drawer side.

Abstract: Methods, systems, and non-transitory computer-readable media are configured to perform operations comprising determining a rescue lane scenario for an environment, determining an amount of lateral bias for a vehicle, and generating planning and control data for the vehicle to laterally bias based on the amount of lateral bias.

Abstract: A transport assembly with an upper part including a plurality of sleeves, each sleeve extending along a sleeve axis between a top opening and a bottom opening, wherein the plurality of sleeves are arranged with their respective axes in parallel to one another, and a lower part including a plate with a plurality of apertures that each extend through the plate. The upper part and the lower part can be coupled such that each bottom opening is arranged adjacent to one of the plurality of apertures, and the upper part and the lower part can be moved relative to one another between a closed configuration in which a perimeter of each bottom opening intersects a perimeter of a corresponding aperture at two or more points, and an open configuration in which the perimeter of each bottom opening is aligned with or is enclosed by the perimeter of a corresponding aperture.

Abstract: Various embodiments herein relate to machinery for forming smoking articles of cannabis compositions. In at least one embodiment, there is provided a system for alcohol-based lubrication for pre-roll machinery comprising: a reservoir tank for retaining lubricant fluid; a tube conduit having a first end fluidically coupled to the reservoir tank and an open second end; and a modified pre-roll member having a fluid-receiving opening coupled to the second tube end, the modified pre-roll member further comprising a bottom contact surface including one or more fluid exit openings coupled to the fluid-receiving opening.

Abstract: Methods and apparatuses control light emitted from a mirror platform through an interaction with a user. A first signal is received from a capacitive sensor during the interaction. The capacitive sensor is incorporated on the back side of the mirror platform. The first signal is processed to obtain control parameters for at least two light sources. The at least two light sources are configured with the mirror platform and the at least two light sources produce light at different color temperatures. The control parameters are used to cause the at least two light sources to emit light at a color temperature established during the interaction.

Abstract: A wirelessly enabled mirror includes a mirror, a wireless data system, and a data output interface. The mirror has a front side and a back side. The wireless data system includes a wireless data module. The wireless data system is fixed to the back side of the mirror. The wireless data module is configured to communicate with a user device and to receive wireless data from the user device. The data output interface is configured to receive data from the wireless data module, and the data is derived from a wireless stream of data.

Abstract: In one example, a proportioning valve, comprises a valve body, a first fitting coupled to the valve body, a second fitting coupled to the valve body, and a third fitting coupled to the valve body, where the second fitting and the third fitting each extend in parallel to the first fitting. In one example, an inner bore of the valve body is substantially cylindrical. In one example, the first fitting is an outlet fitting, the second fitting is a first inlet fitting, and the third fitting is a second inlet fitting. In another example, the first fitting is an inlet fitting, the second fitting is a first outlet fitting, and the third fitting is a second outlet fitting. In one example, the valve body includes a flow diverter positioned within the valve body.

Abstract: An orthopedic instrument system that includes a burr and a burr guide. The burr guide includes an elongated opening, in which at least a portion of the elongated opening includes a substantially circular opening having a greater dimension than that of the adjacent portion of the elongated opening. The circular opening is configured to receive at least a portion of the burr therein and therethrough such that the burr may be manipulated along the length of the elongated opening. The burr has a shaft and a first end opposite a second end with the first end being configured to facilitate being releasably coupled to a tool. The second end of the burr has an engagement feature that is configured to cut and/or resurface a bone surface. A method of using the orthopedic instrument system is also disclosed herein.

Abstract: Methods, systems, and non-transitory computer readable media are configured to perform operations comprising determining an occurrence of a sign in an environment of a vehicle; determining that at least a portion of the sign is unrecognized by a local machine learning model of the vehicle; and providing sensor data associated with the at least one portion of the sign to an operations center remote from the vehicle.

Abstract: Described herein are systems and method for forming cannabis pre-rolls. The method includes the steps of (a) providing a feed of cannabis plant material; (b) trimming the feed of cannabis plant material to form a feed of rollable cannabis plant material having successive first zones and second zones, wherein a cross-sectional area of the first zones in a plane transverse to a feed flow direction through a trimmer is greater than a cross-sectional area of the second zones in a plane transverse to the feed flow direction through the trimmer; and (c) compressing the feed of rollable cannabis plant material to form a feed of compressed rollable cannabis plant material.

Abstract: Transcatheter aortic valve prostheses for improving the cardiac function of a patient suffering from coronary artery disease. Transcatheter aortic valve prostheses include a valve component and a frame. The valve component includes valve leaflets and a skirt. The frame includes access cells that improve access to a patient's coronary arteries if further intervention is required and/or includes a window or conduction protection cell that is oriented to align with a portion of conduction system of the heart in situ to reduce conduction disturbances of the anatomy. Suture patterns for attaching a commissure to a commissure post of the frame, and for attaching a tissue bumper to the commissure post, are also described.

Abstract: Transcatheter aortic valve prostheses for improving the cardiac function of a patient suffering from coronary artery disease. Transcatheter aortic valve prostheses include a valve component and a frame. The valve component includes valve leaflets and a skirt. The frame includes access cells that improve access to a patient's coronary arteries if further intervention is required and/or includes a window or conduction protection cell that is oriented to align with a portion of conduction system of the heart in situ to reduce conduction disturbances of the anatomy. Suture patterns for attaching a commissure to a commissure post of the frame, and for attaching a tissue bumper to the commissure post, are also described.

Abstract: Provided herein is a method of reducing or preventing sunburn caused from visible and ultraviolet radiation in a subject, the method comprising topically applying to the subject a sunscreen composition comprising inorganic UV filtering agents, antioxidants, and at least one inorganic pigment, wherein the at least one inorganic pigments and antioxidants are present in an amount effective to reduce or prevent sunburn caused from visible light. Also provided herein are sunscreen compositions and methods of increasing the SPF of a sunscreen composition that comprises at least one inorganic UV filtering agent.

Abstract: Vehicles and systems and methods for providing rearview displays for vehicles are provided. An exemplary system is provided for a vehicle having a gate moveable between closed configuration and opened configurations. The system includes a camera mounted to the gate and configured to collect dynamic pixel images of an area behind the vehicle; a display screen configured to display the collected dynamic pixel images; and memory configured to include executable instructions and a processor configured to execute executable instructions that enable the processor to crop the collected dynamic pixel images to display a lower portion of the collected dynamic pixel images on the display screen when the gate is in the closed configuration, and to crop the collected dynamic pixel images to display an upper portion of the collected dynamic pixel images on the display screen when the gate is in the opened configuration.

Abstract: The present disclosure relates to a display arrangement, including: a cover that is transparent at least in some regions; a support frame adapted to fix the display arrangement on a supporting structure; a pixel matrix display having a display surface; a housing; wherein the support frame is arranged adjacent to the cover and an intermediate space, which is delimited by the support frame and the cover, is formed and is filled with a thermoplastic elastomer; wherein the cover and the support frame form a well, in which the pixel matrix display is accommodated; wherein a transparent adhesive layer is formed in the well between the display surface and the cover to fix the pixel matrix display on the cover, with the display surface being visible through the cover and the adhesive layer; wherein the housing fits over the pixel matrix display and is fixed on the support frame.

Abstract: Systems are provided for a fluid distribution system of for reconfigurable thermal management. In one example, a fluid distribution system comprises a fluid manifold that includes a plurality of sections with a plurality of inlet and outlet ports, and a pilot assembly including a plurality of manifold sections, a plurality of selectively couplable fluid chambers, and a plurality of solenoid-actuated pilot valve assemblies. The plurality of solenoid-actuated pilot valve assemblies control fluid flow through the plurality of selectively couplable fluid chambers by controlling pressure differential across a plurality of main diaphragms.

Abstract: A lighting system with vacuum intake is provided, having a lighting structure including at least one light-emitting element dimensioned to illuminate a region, and a lighting support structure extending at a first end thereof from the lighting structure and enabling repositioning of the lighting structure relative to a second end of the lighting support structure. The lighting support structure hays an air conduit extending therealong and connectable or connected towards the second end of the lighting support structure to a vacuum system, the air conduit being in fluid communication with a vacuum intake positioned towards the lighting structure.

Abstract: An anchor for wallboard installation includes an elongated anchor body including a driving end and a wall boring end. The anchor body has a main body portion running from the driving end toward the wall boring end. The wall boring end includes a plurality of axially cutting extending teeth. The anchor body includes an internal bore and diametrically opposed slots to facilitate split of an end portion of the anchor body when the anchor is installed in a wall and a fastener is inserted for mounting an object.

Abstract: Provided herein is a method of reducing or preventing sunburn caused from visible and ultraviolet radiation in a subject, the method comprising topically applying to the subject a sunscreen composition comprising inorganic UV filtering agents, antioxidants, and at least one inorganic pigment, wherein the at least one inorganic pigments and antioxidants are present in an amount effective to reduce or prevent sunburn caused from visible light. Also provided herein are sunscreen compositions and methods of increasing the SPF of a sunscreen composition that comprises at least one inorganic UV filtering agent.