Abstract: The present invention relates to treatments of hereditary angioedema (HAE). In particular, the present invention provides on-demand treatments of hereditary angioedema (HAE) by orally administering a plasma kallikrein inhibitor to a patient in need thereof on-demand.

Abstract: The present invention relates at least in part to methods for the manufacture of shape memory polymer (SMP) materials. Particularly, although not exclusive, the present invention relates to processes for the formation of complex shaped devices composed of shape memory polymer.

Abstract: The present invention relates to compositions comprising shape memory polymer (SMP) materials and uses thereof. Particularly, although not exclusively, the present invention relates to biocompatible shape memory polymer (SMP) materials and uses thereof in the medical field.

Abstract: The present invention relates at least in part to surgical devices which comprise a shape memory polymer material composition. Particularly, although not exclusively, the present invention relates to a fixation device e.g. an anchor device e.g. a suture anchor which comprises a shape memory material. Included in the present invention are anchor devices e.g. suture anchors which are formed entirely of a shape memory polymer material. Embodiments of the present invention comprise hybrid suture anchors, particularly suture anchors which are formed from a shape memory polymer material and a non-shape memory material. Methods of securing an anchor in a bone or tissue are also included in the present invention.

Abstract: A method for displaying metadata placed on a document, includes accepting a command to load a document file that corresponds to the document into a memory of a computing device. The method also includes a computer-aided design application accepting, by way of a command line interface, a command to assign a label to each of a plurality of metadata elements in the document file. The method further includes displaying at least one of the plurality of metadata elements in response to a command to display the label assigned to the at least one of the plurality of metadata elements, thereby allowing a user to verify a value of the at least one of the plurality of metadata elements.

Abstract: A method of demonstrating the cleaning performance of a cleaning pad comprises the steps of: (a) providing a soil composition comprising fine particulate matter, optional colorant, and optional dispersant; wherein said soil composition has a mean particle size of from about 1 &mgr;m to about 1,000 &mgr;m; (b) distributing said soil composition on a demonstration surface; and (c) wiping said demonstration surface with said cleaning pad. A soil composition for use in said methods comprises: (a) fine particulate matter; (b) optional colorant; and (c) optional dispersant; wherein said soil composition has a mean particle size of from about 1 &mgr;m to about 1,000 &mgr;m. The soil composition is preferably dispersed in an aqueous carrier to form a soil dispersion.

Abstract: Paper products having high initial wet strengths are disclosed. The paper products comprise cellulosic fibers having free aldehyde groups, which fibers are combined with a water-soluble polymer having functional groups that are reacted with the aldehyde groups to form bonds joining the fibers. In a preferred embodiment, the cellulosic fibers contain a polysaccharide in which the hydroxyl groups of at least a portion of the repeating units of the polysaccharide are cis-hydroxyl groups, preferred repeating units being mannose and/or galactose. Similarly, the water-soluble polymer is preferably a polysaccharide in which the hydroxyl groups of at least a portion of the repeating units of the polysaccharide are cis-hydroxyl groups. Preferred polysaccharides are derived from one or more sugars selected from mannose, galactose, allose, altrose, gulose, talose and lyxose.

Abstract: The present invention relates to paper products having temporary wet strength. The paper products contain cellulosic fibers that are treated with a polyaldehyde polymer having free aldehyde groups and a water soluble polyhydroxy polymer. The initial wet strength obtained with the combined use of these materials is significantly greater than that obtained by use of either the polyaldehyde or pelyhydroxy polymer alone. At the same time, the wet strength decays at a rate that is rapid enough to enable the paper product to be flushed under conditions of normal use.

Abstract: A temporary wet strength polymer and compositions for paper products, e.g., toilet tissue, is disclosed. The temporary wet strength polymer is the oxidation product of an esterified polyhydroxy polymer, more preferably of an esterified polysaccharide. The esterified polymer compound is formed by reacting the polyhydroxy polymer with a 1,2-disubstituted alkene compound that has at least one carboxylic acid group. The temporary wet strength polymer provides paper products having an initial wet strength that enables use of the product in the moistened condition, along with a suitable wet strength decay rate.