Patents by Inventor Michael Massare

Michael Massare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic middle east respiratory syndrome coronavirus (MERS-CoV) compositions and methods
    Patent number: 10751410
    Abstract: Disclosed herein are nanoparticles containing MERS virus proteins in polymer structures, and compositions containing the nanoparticles formulated for administration as immunogenic compositions. Also provided herein are vector constructs encoding the proteins, and host cells containing the vector constructs. The disclosure also includes methods of making the nanoparticles and administering them to vertebrates, including methods of inducing immune responses to MERS that reduce or prevent infection by the virus.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: August 25, 2020
    Assignee: Novavax, Inc.
    Inventors: Gale Smith, Ye Liu, Michael Massare
  • RECOMBINANT NANOPARTICLE RSV F VACCINE FOR RESPIRATORY SYNCYTIAL VIRUS
    Publication number: 20170319682
    Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
    Type: Application
    Filed: February 15, 2017
    Publication date: November 9, 2017
    Inventors: Gale SMITH, Yingyun WU, Michael MASSARE, Ye LIU
  • Highly efficient influenza matrix (M1) proteins
    Patent number: 9464276
    Abstract: This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: October 11, 2016
    Assignee: Novavax, Inc.
    Inventors: Gale Smith, Yingyun Wu, Michael Massare, Peter Pushko, Margaret Nathan, Thomas Kort, Robin Robinson
  • IMMUNOGENIC MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS (MERS-CoV) COMPOSITIONS AND METHODS
    Publication number: 20160206729
    Abstract: Disclosed herein are nanoparticles containing MERS virus proteins in polymer structures, and compositions containing the nanoparticles formulated for administration as immunogenic compositions. Also provided herein are vector constructs encoding the proteins, and host cells containing the vector constructs. The disclosure also includes methods of making the nanoparticles and administering them to vertebrates, including methods of inducing immune responses to MERS that reduce or prevent infection by the virus.
    Type: Application
    Filed: September 19, 2014
    Publication date: July 21, 2016
    Inventors: Gale SMITH, Ye LIU, Michael MASSARE
  • RECOMBINANT NANOPARTICLE RSV F VACCINE FOR RESPIRATORY SYNCYTIAL VIRUS
    Publication number: 20150335730
    Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
    Type: Application
    Filed: February 27, 2015
    Publication date: November 26, 2015
    Inventors: Gale SMITH, Yingyun WU, Michael MASSARE, Ye LIU
  • HIGHLY EFFICIENT INFLUENZA MATRIX (M1) PROTEINS
    Publication number: 20150307849
    Abstract: This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
    Type: Application
    Filed: February 23, 2015
    Publication date: October 29, 2015
    Inventors: Gale SMITH, Yingyun WU, Michael MASSARE, Peter PUSHKO, Margaret NATHAN, Thomas KORT, Robin ROBINSON
  • RECOMBINANT NANOPARTICLE RSV F VACCINE FOR RESPIRATORY SYNCYTIAL VIRUS
    Publication number: 20150306207
    Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
    Type: Application
    Filed: February 27, 2015
    Publication date: October 29, 2015
    Inventors: Gale SMITH, Yingyun WU, Michael MASSARE, Ye LIU
  • Highly efficient influenza matrix (M1) proteins
    Patent number: 8992939
    Abstract: This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: March 31, 2015
    Assignee: Novavax, Inc.
    Inventors: Gale Smith, Yingyun Wu, Michael Massare, Peter Pushko, Margret Nathan, Thomas Kort, Robin Robinson
  • Modified RSV F proteins and methods of their use
    Patent number: 8715692
    Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: May 6, 2014
    Assignee: Novavax, Inc.
    Inventors: Peter Pushko, Yingyun Wu, Michael Massare, Ye Liu, Gale Smith, Bin Zhou
  • RECOMBINANT NANOPARTICLE RSV F VACCINE FOR RESPIRATORY SYNCYTIAL VIRUS
    Publication number: 20130122032
    Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
    Type: Application
    Filed: September 27, 2012
    Publication date: May 16, 2013
    Inventors: Gale SMITH, Yingyun Wu, Michael Massare, Ye Liu
  • HIGHLY EFFICIENT INFLUENZA MATRIX (M1) PROTEINS
    Publication number: 20130039938
    Abstract: This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
    Type: Application
    Filed: October 24, 2011
    Publication date: February 14, 2013
    Applicant: NOVAVAX, INC.
    Inventors: Gale SMITH, Yingyun Wu, Michael Massare, Peter Pushko, Margret Nathan, Thomas Kort, Robin Robinson
  • MODIFIED RSV F PROTEINS AND METHODS OF THEIR USE
    Publication number: 20100239617
    Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
    Type: Application
    Filed: December 9, 2009
    Publication date: September 23, 2010
    Inventors: Peter PUSHKO, Yingyun Wu, Michael Massare, Ye Liu, Gale Smith, Bin Zhou